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Caseína quinasa

Caseína quinasa

Las caseína quinasas son una familia de quinasas de proteínas serina/treonina que regulan varios procesos celulares, incluyendo la reparación del ADN, los ritmos circadianos y la transducción de señales. Estas quinasas están involucradas en la fosforilación de numerosas proteínas y están implicadas en enfermedades como el cáncer, los trastornos neurodegenerativos y los síndromes metabólicos. En CymitQuimica, ofrecemos una selección de inhibidores de caseína quinasa para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.

Se han encontrado 130 productos de "Caseína quinasa"

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  • HDAC/CK2-IN-1

    CAS:
    <p>HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.</p>
    Fórmula:C15H18Br4N4O2
    Forma y color:Solid
    Peso molecular:605.95
  • CK2-IN-4

    CAS:
    <p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>
    Fórmula:C18H11N3O4S
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:365.36
  • CK2α-IN-1

    CAS:
    <p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>
    Fórmula:C16H11N3O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:341.34
  • CK1-IN-2

    CAS:
    <p>CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.</p>
    Fórmula:C17H12FN3O2
    Pureza:99.31%
    Forma y color:Solid
    Peso molecular:309.29
  • PI-828

    CAS:
    <p>PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.</p>
    Fórmula:C19H18N2O3
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:322.36
  • XL413 xHCl

    CAS:
    <p>BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215</p>
    Fórmula:C14H12ClN3O2·xHCl
    Pureza:99.37% - 99.67%
    Forma y color:Solid
    Peso molecular:326.18
  • BioE-1115

    CAS:
    <p>BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).</p>
    Fórmula:C19H18FN3O2
    Pureza:97.54%
    Forma y color:Solid
    Peso molecular:339.36
  • Casein kinase 1δ-IN-1

    CAS:
    <p>Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.</p>
    Fórmula:C11H7N3OS
    Pureza:99.46%
    Forma y color:Solid
    Peso molecular:229.26
  • Ac-VDVAD-CHO

    CAS:
    <p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>
    Fórmula:C23H37N5O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:543.57
  • ON 108600

    CAS:
    <p>ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.</p>
    Fórmula:C22H14Cl2N2O6S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:537.39
  • Casein kinase 1δ-IN-5

    CAS:
    <p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>
    Fórmula:C16H11F3N2OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:336.33
  • Casein kinase 1δ-IN-10

    CAS:
    <p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>
    Fórmula:C21H17N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:359.38
  • TID43

    CAS:
    <p>TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].</p>
    Fórmula:C10H3I4NO4
    Forma y color:Solid
    Peso molecular:708.755
  • XL413 hydrochloride

    CAS:
    <p>XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.</p>
    Fórmula:C14H13Cl2N3O2
    Pureza:98.81% - 99.8%
    Forma y color:Solid
    Peso molecular:326.18
  • Casein kinase 1δ-IN-4

    CAS:
    <p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>
    Fórmula:C16H12N6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:320.37
  • Casein Kinase II Inhibitor IV

    CAS:
    <p>Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.</p>
    Fórmula:C24H23N5O3
    Pureza:99.65% - 99.75%
    Forma y color:Solid
    Peso molecular:429.47
  • Casein kinase 1δ-IN-13

    CAS:
    Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.
    Fórmula:C15H13N3O2S
    Forma y color:Solid
    Peso molecular:299.35
  • Casein kinase 1δ-IN-28

    CAS:
    <p>Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.</p>
    Fórmula:C23H23FN6
    Forma y color:Solid
    Peso molecular:402.467
  • CK1δ-IN-6

    CAS:
    <p>CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.</p>
    Fórmula:C23H17N3O4
    Forma y color:Solid
    Peso molecular:399.399
  • WAY-606344

    CAS:
    <p>WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.</p>
    Fórmula:C14H8ClN3O2
    Forma y color:Solid
    Peso molecular:285.685