Caseína quinasa
Las caseína quinasas son una familia de quinasas de proteínas serina/treonina que regulan varios procesos celulares, incluyendo la reparación del ADN, los ritmos circadianos y la transducción de señales. Estas quinasas están involucradas en la fosforilación de numerosas proteínas y están implicadas en enfermedades como el cáncer, los trastornos neurodegenerativos y los síndromes metabólicos. En CymitQuimica, ofrecemos una selección de inhibidores de caseína quinasa para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 150 productos para "Caseína quinasa".
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XL413 hydrochloride
CAS:XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.Fórmula:C14H13Cl2N3O2Pureza:98.81% - 99.8%Forma y color:SolidPeso molecular:326.18Ref: TM-T6735
1mg50,00€5mg109,00€10mg152,00€25mg268,00€50mg447,00€100mg672,00€200mg888,00€500mg1.369,00€Casein kinase 1δ-IN-10
CAS:Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Fórmula:C21H17N3O3Pureza:98%Forma y color:SolidPeso molecular:359.38Ac-VDVAD-CHO
CAS:Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].Fórmula:C23H37N5O10Pureza:98%Forma y color:SolidPeso molecular:543.57CK1δ-IN-9
CAS:CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.Fórmula:C16H12FN5Forma y color:SolidPeso molecular:293.298CK1δ-IN-7
CAS:CK1δ-IN-7 (Compound 488) is an inhibitor of casein kinase 1δ (CK1δ).Fórmula:C23H23N5OForma y color:SolidPeso molecular:385.462CK1δ-IN-1
CAS:CK1δ-IN-1 (example 939) is an inhibitor of casein kinase 1δ (CK1δ). CK1δ-IN-1 is utilized for research in Alzheimer's disease.Fórmula:C21H17N5Peso molecular:339.3932Casein kinase 1δ-IN-27
CAS:Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.Fórmula:C21H19FN6Forma y color:SolidPeso molecular:374.414CK1δ-IN-5
CAS:CK1δ-IN-5 (Compound 24) is an inhibitor of casein kinase 1δ (CK1δ) and can be used in the study of neurodegenerative diseases.Fórmula:C22H21N5Forma y color:SolidPeso molecular:355.436WAY-606344
CAS:WAY-606344 (Compound 97) is an inhibitor of Casein kinase 1δ and shows potential for Alzheimer's disease research.Fórmula:C14H8ClN3O2Forma y color:SolidPeso molecular:285.685CK1δ-IN-6
CAS:CK1δ-IN-6 (Compound 303) is an inhibitor of Casein kinase 1δ, with potential applications in Alzheimer's disease research.Fórmula:C23H17N3O4Forma y color:SolidPeso molecular:399.399Casein kinase 1δ-IN-28
CAS:Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.Fórmula:C23H23FN6Forma y color:SolidPeso molecular:402.467Casein kinase 1δ-IN-17
CAS:Casein kinase1δ-IN-17 (compound 753) is an inhibitor of casein kinase 1δ (CK1δ). It is applicable in research related to neurodegenerative diseases.Fórmula:C14H14N4SForma y color:SolidPeso molecular:270.353MGD-28
CAS:MGD-28 is a Cullin-CRBN-dependent IKZF family protein degrader for IKZF1 (Ikaros), IKZF2 (Helios), IKZF3 (Aiolos) ,and CK1α, antiproliferative.Fórmula:C33H34FN7O3Pureza:99.39%Forma y color:SolidPeso molecular:595.67TMX-4113
TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].Fórmula:C12H12N4O2S2Forma y color:SolidPeso molecular:308.38Casein kinase 1δ-IN-23
CAS:Casein kinase1δ-IN-23 (compound 423) is an effective inhibitor of casein kinase1δ. It is applicable in research related to neurodegenerative diseases such as Alzheimer's disease.Fórmula:C19H15N3O3SForma y color:SolidPeso molecular:365.406CK2-IN-3
CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.Fórmula:C22H26N4O7Forma y color:SolidPeso molecular:458.46Casein Kinase II Inhibitor IV Hydrochloride
CAS:Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.Fórmula:C24H24ClN5O3Pureza:98%Forma y color:SolidPeso molecular:465.93CK2 inhibitor 3
CK2 inhibitor 3: potent CK2 blocker, IC50 of 280 nM, suppresses tumor cell growth, highly selective among 320 kinases.Fórmula:C13H9BrN4O3SForma y color:SolidPeso molecular:381.2TMX-4116
CAS:TMX-4116 is a CK1α degrader targeting multiple cell lines with DC50s below 200 nM, used in multiple myeloma research and protein degradation strategy studies.Fórmula:C17H19N5O4SForma y color:White SolidPeso molecular:389.43CX-5279
CAS:CX-5279 is a potent and selective CK2 inhibitor, exhibiting IC50 values of 2.73 nM for nCK2 and 0.91 nM for CK2α. It shows sensitivity to mutations Val66, Ile174, and V66I174AA, with IC50 values of 13.8 nM, 12.5 nM, and 23.35 nM, respectively, and demonstrates weak inhibitory activity against PIM1 with an IC50 of 8.52 μM. CX-5279 displays antiproliferative activity across various cancer cell lines and can be used in research on cancers such as pancreatic cancer and leukemia.Fórmula:C22H17F3N5NaO2Peso molecular:463.4
