Anhídrido carbónico
La anhidrasa carbónica es una enzima que cataliza la conversión reversible de dióxido de carbono y agua en bicarbonato y protones. Esta enzima juega un papel crucial en el mantenimiento del equilibrio ácido-base, la respiración y el transporte de dióxido de carbono en la sangre. Los inhibidores de la anhidrasa carbónica se utilizan en el tratamiento del glaucoma, la epilepsia y el mal de altura, así como en la investigación sobre la homeostasis ácido-base y el intercambio de gases. En CymitQuimica, ofrecemos una gama de inhibidores de la anhidrasa carbónica y reactivos de alta calidad para apoyar su investigación en enzimología, fisiología respiratoria y desarrollo terapéutico.
Se han encontrado 196 productos de "Anhídrido carbónico"
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4-(benzyloxy)benzene-1-sulfonamide
CAS:4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.Fórmula:C13H13NO3SPureza:97.54%Forma y color:SolidPeso molecular:263.31EMAC10101d
CAS:compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with anFórmula:C17H15Cl2N3O2S2Pureza:99.96%Forma y color:SolidPeso molecular:428.36WES-1
CAS:WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,Fórmula:C20H20N4O3SPureza:98%Forma y color:SolidPeso molecular:396.46AHR-15010
CAS:AHR-15010 is a novel anti-arthritic agent.Fórmula:C10H16N2O8S2Pureza:98%Forma y color:SolidPeso molecular:356.37hCAIX-IN-11
CAS:hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.Fórmula:C21H15ClN4O3Forma y color:SolidPeso molecular:406.82hCAXII-IN-4
CAS:hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.Fórmula:C22H27N5O6SForma y color:SolidPeso molecular:489.54Methazolamide-d6
CAS:Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.Fórmula:C5H2D6N4O3S2Forma y color:SolidPeso molecular:242.31L 662583
CAS:L 662583 is a topical inhibitor of carbonic anhydrase.Fórmula:C13H17ClN2O5S3Pureza:98%Forma y color:SolidPeso molecular:412.93hCAI/II-IN-1
CAS:hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).Fórmula:C18H29N5O3S3Forma y color:SolidPeso molecular:459.65hCAI/II-IN-2
CAS:hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.Fórmula:C12H12N4O5S2Forma y color:SolidPeso molecular:356.38hCA IX-IN-2
hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferativeFórmula:C23H24N2O4STeForma y color:SolidPeso molecular:552.11hCAIX-IN-14
CAS:hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .Fórmula:C11H17ClN6O2SForma y color:SolidPeso molecular:332.81hCAI/II-IN-3
CAS:"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."Fórmula:C16H18N4O4S2Forma y color:SolidPeso molecular:394.47hCAIX-IN-3
CAS:hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.Fórmula:C21H21BrN6O4SForma y color:SolidPeso molecular:533.4hCAIX/XII-IN-6
hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.Fórmula:C26H23N3O6S4Forma y color:SolidPeso molecular:601.74L-693612 HCl
CAS:L-693612 HCl is an inhibitor of carbonic anhydrase.Fórmula:C14H25ClN2O5S3Pureza:98%Forma y color:SolidPeso molecular:433.01hCAIX/XII-IN-2
CAS:Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).Fórmula:C19H14N2O4Forma y color:SolidPeso molecular:334.33CDK2-IN-12
CAS:CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.Fórmula:C20H17N9O2SForma y color:SolidPeso molecular:447.47Clofenamide
CAS:Clofenamide is a low-ceiling sulfonamide diuretic.Fórmula:C6H7ClN2O4S2Forma y color:SolidPeso molecular:270.71hCAII-IN-1
CAS:hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.Fórmula:C21H21BrN6O4SForma y color:SolidPeso molecular:533.4
