HMG-CoA reductasa
La HMG-CoA Reductasa es una enzima clave en la vía del mevalonato, responsable de la síntesis de colesterol y otros isoprenoides. Los inhibidores de la HMG-CoA reductasa, comúnmente conocidos como estatinas, se utilizan ampliamente para reducir los niveles de colesterol y disminuir el riesgo de enfermedades cardiovasculares. Estos inhibidores también tienen beneficios potenciales en la investigación sobre el cáncer y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una variedad de inhibidores de la HMG-CoA reductasa para apoyar su investigación en el metabolismo lipídico, la salud cardiovascular y el desarrollo terapéutico.
Se han encontrado 33 productos de "HMG-CoA reductasa"
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Monacolin J
CAS:<p>Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.</p>Fórmula:C19H28O4Pureza:98.06%Forma y color:SolidPeso molecular:320.42Atorvastatin lactone
CAS:<p>Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.</p>Fórmula:C33H33FN2O4Pureza:98.05% - 98.16%Forma y color:SolidPeso molecular:540.62(3S,5R)-Fluvastatin D6 sodium
CAS:<p>(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.</p>Fórmula:C24H25FNNaO4Pureza:98%Forma y color:SolidPeso molecular:439.49Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Forma y color:Odour SolidL 645164
CAS:<p>L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.</p>Fórmula:C22H23FO3Forma y color:SolidPeso molecular:354.4124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Fórmula:C27H44O2Peso molecular:400.64HMG-CoA Reductase-IN-1
<p>HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKm</p>Fórmula:C27H29N3O7Forma y color:SolidPeso molecular:507.54(Rac)-5-Keto Fluvastatin
CAS:<p>(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.</p>Fórmula:C24H24FNO4Pureza:95.04%Forma y color:SolidPeso molecular:409.45Ganoderenic acid K
CAS:<p>Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.</p>Fórmula:C32H44O9Forma y color:SolidPeso molecular:572.69Rawsonol
CAS:<p>Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.</p>Fórmula:C29H24Br4O7Forma y color:SolidPeso molecular:804.11PPD 10558
CAS:<p>PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.</p>Fórmula:C34H37FN2O6Forma y color:SolidPeso molecular:588.67Pravastatin lactone
CAS:<p>Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.</p>Fórmula:C23H34O6Forma y color:SolidPeso molecular:406.519Atorvastatin calcium trihydrate
CAS:<p>Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.</p>Fórmula:C66H74CaF2N4O13Forma y color:SolidPeso molecular:1209.39SR12813
CAS:<p>SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.</p>Fórmula:C24H42O7P2Pureza:99.43%Forma y color:SolidPeso molecular:504.53Clinofibrate
CAS:<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Fórmula:C28H36O6Pureza:>99.99%Forma y color:White Crystalline PowderPeso molecular:468.587-Ketocholesterol
CAS:<p>7-Ketocholesterol is a metabolite of Cholesterol</p>Fórmula:C27H44O2Pureza:97.59% - 98.84%Forma y color:SolidPeso molecular:400.65Tenivastatin
CAS:<p>Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.</p>Fórmula:C25H40O6Pureza:99.56%Forma y color:SolidPeso molecular:436.58Simvastatin acid ammonium
CAS:<p>Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.</p>Fórmula:C25H43NO6Pureza:98.3%Forma y color:SolidPeso molecular:453.61Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Fórmula:C33H35FN2O5Pureza:99.37% - 99.69%Forma y color:SolidPeso molecular:558.64(3S,5R)-Fluvastatin sodium
CAS:<p>(3S,5R)-Fluvastatin sodium: synthetic HMG-CoA reductase inhibitor, IC50 8 nM, boosts vascular cell antioxidant defense.</p>Fórmula:C24H26FNNaO4Pureza:98%Forma y color:SolidPeso molecular:434.463Lovastatin hydroxy acid sodium
CAS:<p>Lovastatin Sodium is an HMG-CoA reductase inhibitor.</p>Fórmula:C24H38NaO6Forma y color:SolidPeso molecular:445.54(Z)-Pitavastatin calcium
CAS:<p>(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.</p>Fórmula:C50H50CaF2N2O8Pureza:98%Forma y color:SolidPeso molecular:885.031(3S,5R)-Pitavastatin calcium
CAS:<p>(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.</p>Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562(3S,5S)-Pitavastatin calcium
CAS:<p>(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.</p>Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562Crilvastatin
CAS:<p>Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.</p>Fórmula:C14H23NO3Pureza:98.69% - 99.54%Forma y color:SolidPeso molecular:253.34Simvastatin acid calcium hydrate
CAS:<p>Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.</p>Fórmula:C25H40O6Forma y color:SolidPeso molecular:436.28249L 669262
CAS:<p>L 669262 is a potent inhibitor of HMG-CoA reductase.</p>Fórmula:C25H36O6Forma y color:SolidPeso molecular:432.554-Acetylsimvastatin
CAS:<p>4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).</p>Fórmula:C27H40O6Pureza:98%Forma y color:SolidPeso molecular:460.62'-Ethyl Simvastatin
CAS:<p>2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.</p>Fórmula:C23H34O5Pureza:98%Forma y color:SolidPeso molecular:390.51Dalvastatin
CAS:<p>Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepatic</p>Fórmula:C24H31FO3Pureza:98.80%Forma y color:SolidPeso molecular:386.5QH536
CAS:<p>QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.</p>Fórmula:C33H49N3O3Forma y color:SolidPeso molecular:535.76Bemfivastatin hemicalcium
CAS:<p>Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.</p>Fórmula:C34H36FN2O6CaForma y color:SolidPeso molecular:607.67L 668411
CAS:<p>L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.</p>Fórmula:C19H30O5Pureza:98%Forma y color:SolidPeso molecular:338.44
