Transferasa
Las transferasas son una gran clase de enzimas que catalizan la transferencia de grupos funcionales, como grupos metilo, glicosilo y fosfato, de una molécula a otra. Los inhibidores de transferasas se utilizan para estudiar una amplia gama de procesos biológicos, incluyendo la transducción de señales, el metabolismo y la expresión génica. Estos inhibidores son herramientas esenciales en áreas de investigación como el cáncer, las enfermedades metabólicas y la epigenética, donde está implicada la disfunción de la actividad de las transferasas. En CymitQuimica, ofrecemos una selección integral de inhibidores de transferasas para apoyar su investigación en enzimología, señalización celular y mecanismos de enfermedad.
Se han encontrado 35 productos para "Transferasa".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Cycloleucine
CAS:Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM.Fórmula:C6H11NO2Pureza:99.90%Forma y color:SolidPeso molecular:129.16Opicapone
CAS:Opicapone (BIA 9-1067), a potent COMT inhibitor for Parkinson's studies, lowers cell ATP (IC50: 98 μM).Fórmula:C15H10Cl2N4O6Pureza:98.17% - 99.36%Forma y color:SolidPeso molecular:413.17β-1,4-GALT1-IN-1
β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor with an IC50 value of 6.2 μM. It is applicable in studying various pathological conditions, including cancer, autoimmune diseases, and viral infections.Fórmula:C29H23NO10Forma y color:SolidPeso molecular:545.494R1-11
R1-11 is an indole-based ICMT inhibitor with an IC50 of 0.6 μM, exhibiting anticancer properties. It inhibits MDA-MB231 and PC3 cells with IC50 values of 2.2 μM and 2.0 μM, respectively.Fórmula:C25H37N5Peso molecular:407.3049Squalene synthase-IN-2
Squalene synthase-IN-2 (compound isomer A-(1S, 3R)-14i) is an orally active inhibitor of squalene synthase, with IC50 values of 3.4 nM for squalene synthase and 99 nM for cholesterol synthesis enzymes. Squalene synthase-IN-2 effectively reduces plasma cholesterol and triglycerides.Fórmula:C31H39ClN2O6Peso molecular:570.24966Sinbaglustat
CAS:Sinbaglustat (OGT2378), an oral N-alkyl iminosugar, inhibits GCS/GBA2 and treats lysosomal storage and neurodegenerative disorders.
Fórmula:C11H23NO4Pureza:99.93%Forma y color:SolidPeso molecular:233.3Histamine glutarimide
CAS:Histamine glutarimide is a novel QPCT inhibitor that targets inflammatory processes like eosinophil migration, showing anti-asthmatic effects in animal models.Fórmula:C10H13N3O2Pureza:99.79%Forma y color:SolidPeso molecular:207.23L-739750 2HCl
L-739750 2HCl is a potent inhibitor of peptidomimetic farnesyltransferase, a novel pseudopeptide mimetic with potential anticancer activity.Fórmula:C23H41Cl2N3O6S2Pureza:98.69% - 99.16%Forma y color:SoildPeso molecular:590.62FUT8-IN-1
FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.Fórmula:C23H25ClN2OForma y color:SolidPeso molecular:380.91FTI-277
CAS:FTI-277, an FTase inhibitor, blocks H-Ras/K-Ras signaling and HDV infection; mimics Ras CAAX peptide.Fórmula:C22H29N3O3S2Forma y color:SolidPeso molecular:447.61BAY-593
CAS:BAY-593 is an orally active GGTase-I inhibitor capable of blocking YAP1/TAZ signaling in vivo, exhibiting antitumor activity.Fórmula:C26H31F3N2O3Forma y color:SolidPeso molecular:476.53Ervogastat
CAS:Ervogastat (PF-06865571) is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor.Fórmula:C21H21N5O4Pureza:99.97%Forma y color:SolidPeso molecular:407.42Ref: TM-T9186
1mg123,00€5mg290,00€1mL*10mM (DMSO)301,00€10mg485,00€25mg782,00€50mg1.063,00€100mg1.431,00€Ibiglustat
CAS:Ibiglustat (GZ402671) inhibits Glucosylceramide synthase, may treat Fabry disease by preventing GL-3 synthesis.Fórmula:C20H24FN3O2SPureza:97.97% - 98.81%Forma y color:SolidPeso molecular:389.49Tipifarnib (S enantiomer)
CAS:Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).Fórmula:C27H22Cl2N4OPureza:99.05%Forma y color:SolidPeso molecular:489.4Ref: TM-T17102
1mg49,00€5mg102,00€1mL*10mM (DMSO)109,00€10mg163,00€25mg284,00€50mg409,00€100mg577,00€200mg778,00€PD 128042
CAS:PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor.Fórmula:C23H39NO4Pureza:99.79%Forma y color:SolidPeso molecular:393.56CP-609754
CAS:CP-609754 shows selective inhibition of farnesyltransferase.Fórmula:C29H22ClN3O2Pureza:99.86% - 99.87%Forma y color:SolidPeso molecular:479.96Ref: TM-T38050
1mg52,00€5mg110,00€1mL*10mM (DMSO)127,00€10mg177,00€25mg301,00€50mg425,00€100mg605,00€200mg797,00€Entacapone
CAS:Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).Fórmula:C14H15N3O5Pureza:98.80% - >99.99%Forma y color:Yellow Crystalline SolidPeso molecular:305.29Ref: TM-T2216
5mg34,00€10mg49,00€1mL*10mM (DMSO)50,00€25mg75,00€50mg90,00€100mg137,00€200mg197,00€500mg333,00€Tipifarnib
CAS:Tipifarnib (IND 58359), a quinolinone, inhibits farnesyl transferase, blocks Ras activation, arrests cell growth, and curbs angiogenesis.Fórmula:C27H22Cl2N4OPureza:97.1% - 99.22%Forma y color:Off-White To Pale Beige SolidPeso molecular:489.4Nitecapone
CAS:Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)Fórmula:C12H11NO6Pureza:98.39%Forma y color:SolidPeso molecular:265.223-O-Methyltolcapone
CAS:3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.Fórmula:C15H13NO5Pureza:98%Forma y color:SolidPeso molecular:287.27
