Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 269 productos de "Deshidrogenasa"
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Tiazofurin
CAS:<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.27MK-8245
CAS:<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Fórmula:C17H16BrFN6O4Pureza:97.58% - 99%Forma y color:SolidPeso molecular:467.25NCT-501 hydrochloride
CAS:<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Fórmula:C21H33ClN6O3Forma y color:SolidPeso molecular:452.98Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Fórmula:C20H18FNO4CaForma y color:SolidPeso molecular:375.4AG-636
CAS:<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Fórmula:C21H17N3O2Pureza:99.19%Forma y color:SolidPeso molecular:343.38Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Forma y color:White PowderPeso molecular:150.92A939572
CAS:<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Fórmula:C20H22ClN3O3Pureza:99.96% - ≥95%Forma y color:SolidPeso molecular:387.86Proguanil hydrochloride
CAS:<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Fórmula:C11H17Cl2N5Pureza:98.34% - 98.39%Forma y color:SolidPeso molecular:290.19Ivosidenib
CAS:<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Fórmula:C28H22ClF3N6O3Pureza:98.71% - 99.98%Forma y color:SolidPeso molecular:582.96Perfluorooctanoic acid
CAS:<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Fórmula:C8HF15O2Pureza:99.70%Forma y color:White To Off-White Powder OthersolidPeso molecular:414.07Galloflavin
CAS:<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Fórmula:C12H6O8Pureza:96.24% - 97.47%Forma y color:SolidPeso molecular:278.17NCT-505
CAS:<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Fórmula:C27H28FN5O3SPureza:99.93%Forma y color:SolidPeso molecular:521.61VER-246608
CAS:<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Fórmula:C28H23ClF2N4O4Pureza:98.5%Forma y color:SolidPeso molecular:552.96Mutant IDH1-IN-1
CAS:<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Fórmula:C30H31FN4O2Pureza:99.49% - >99.99%Forma y color:SolidPeso molecular:498.59NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C20H23F3N4SPureza:98.91% - 99.84%Forma y color:SolidPeso molecular:408.48L-Allylglycine
CAS:<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Fórmula:C5H9NO2Pureza:≥98%Forma y color:White To Off-White Crystalline PowderPeso molecular:115.13CM10
CAS:<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Fórmula:C20H23N3OPureza:99.84%Forma y color:SolidPeso molecular:321.42NCT-501
CAS:<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Fórmula:C21H32N6O3Pureza:99.19%Forma y color:SolidPeso molecular:416.52AGI-5198
CAS:<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Fórmula:C27H31FN4O2Pureza:97.37% - 99.23%Forma y color:SolidPeso molecular:462.56Nifurtimox
CAS:<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Fórmula:C10H13N3O5SPureza:99.87% - 99.89%Forma y color:SolidPeso molecular:287.29BAY-1436032
CAS:<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Fórmula:C26H30F3N3O3Pureza:99.65% - 99.71%Forma y color:SolidPeso molecular:489.53WIN 18446
CAS:<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Fórmula:C12H20Cl4N2O2Pureza:99.69%Forma y color:SolidPeso molecular:366.11Brequinar sodium
CAS:<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Fórmula:C23H14F2NNaO2Pureza:98.16%Forma y color:SolidPeso molecular:397.36Fomepizole
CAS:<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Fórmula:C4H6N2Pureza:98.1% - 99.94%Forma y color:Yellow <13°C Solid >13°C LiquidPeso molecular:82.1Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Fórmula:C6H8N2O2Pureza:99.62%Forma y color:SolidPeso molecular:140.14AG-120 (racemic)
CAS:<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Fórmula:C28H22ClF3N6O3Pureza:99.56%Forma y color:SolidPeso molecular:582.96Vidofludimus
CAS:<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36BVT-14225
CAS:<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Fórmula:C16H20ClN3O3S2Pureza:97.78%Forma y color:SolidPeso molecular:401.93(R)-GNE-140
CAS:<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Fórmula:C25H23ClN2O3S2Pureza:98.25% - 98.91%Forma y color:SolidPeso molecular:499.04Succinyl phosphonate trisodium salt
CAS:<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Fórmula:C4H4Na3O6PPureza:99.8% - ≥95%Forma y color:SolidPeso molecular:248.01SW033291
CAS:<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Fórmula:C21H20N2OS3Pureza:97.26% - 99.02%Forma y color:SolidPeso molecular:412.593-Hydroxybenzaldehyde
CAS:<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Fórmula:C7H6O2Pureza:99.60%Forma y color:DrypowderPeso molecular:122.126PGD-IN-S3
CAS:<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Fórmula:C15H10O4Pureza:99.12%Forma y color:SolidPeso molecular:254.24Enasidenib
CAS:<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Fórmula:C19H17F6N7OPureza:98% - >99.99%Forma y color:SolidPeso molecular:473.38DS44960156
CAS:<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Fórmula:C20H15NO5Pureza:99.13%Forma y color:SolidPeso molecular:349.34Enasidenib mesylate
CAS:<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Fórmula:C20H21F6N7O4SPureza:99.86%Forma y color:SolidPeso molecular:569.48GSK1940029
CAS:<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Fórmula:C18H16Cl2N4O2Pureza:99.48% - 99.49%Forma y color:SolidPeso molecular:391.25Triflupromazine
CAS:<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Fórmula:C18H19F3N2SForma y color:SolidPeso molecular:352.42hDHODH-IN-2
CAS:<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Fórmula:C19H16N2O2Pureza:98%Forma y color:SolidPeso molecular:304.349Nitrophenide
CAS:<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Fórmula:C12H8N2O4S2Pureza:99.78%Forma y color:SolidPeso molecular:308.3311β-HSD1-IN-6
CAS:<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Fórmula:C21H19ClN4OForma y color:SolidPeso molecular:378.86DHODH-IN-17
CAS:<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Fórmula:C12H9ClN2O2Pureza:99.41% - 99.52%Forma y color:SolidPeso molecular:248.67IMB-XMA0038
CAS:<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Fórmula:C11H10N4O6Pureza:98.94% - 99.96%Forma y color:SolidPeso molecular:294.22Nitrefazole
CAS:<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Fórmula:C10H8N4O4Forma y color:SolidPeso molecular:248.19DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Fórmula:C21H20F3N3O2Pureza:99.76%Forma y color:SolidPeso molecular:403.4hDHODH-IN-5
CAS:<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Fórmula:C21H21F3N2O2Pureza:99.55%Forma y color:SolidPeso molecular:390.4p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Fórmula:C11H14O2Pureza:99.87%Forma y color:White To Light Beige PowderPeso molecular:178.2311β-HSD1-IN-1
CAS:<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Fórmula:C18H14ClF4N3OPureza:99.84%Forma y color:SolidPeso molecular:399.77NCT-506
CAS:<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Fórmula:C25H23FN4O3SPureza:98%Forma y color:SolidPeso molecular:478.54SCH-451659
CAS:<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Fórmula:C30H39Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:544.56
