AhR
El Receptor de Hidrocarburos Aromáticos (AhR) es un factor de transcripción activado por ligandos que desempeña un papel crítico en la regulación de las respuestas biológicas a contaminantes ambientales, como las dioxinas. AhR también está involucrado en el metabolismo de xenobióticos y en la regulación de las respuestas inmunitarias, la proliferación y la diferenciación celular. La desregulación de la señalización de AhR está vinculada a diversas enfermedades, incluido el cáncer y los trastornos autoinmunes. En CymitQuimica, ofrecemos una gama de inhibidores de AhR para apoyar su investigación en toxicología, biología del cáncer e inmunología.
Se han encontrado 41 productos de "AhR"
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L-Kynurenine
CAS:<p>L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!</p>Fórmula:C10H12N2O3Pureza:98.44% - 99.91%Forma y color:Light Yellow CrystallinePeso molecular:208.21BAY-218
CAS:<p>Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.</p>Fórmula:C20H17ClFN3O3Pureza:99.46% - 99.85%Forma y color:SolidPeso molecular:401.82Carbidopa
CAS:<p>Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).</p>Fórmula:C10H14N2O4Pureza:98.01% - ≥98%Forma y color:SolidPeso molecular:226.23Tapinarof
CAS:<p>Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.</p>Fórmula:C17H18O2Pureza:99.64% - >99.99%Forma y color:SolidPeso molecular:254.32PDM11
CAS:<p>PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)</p>Fórmula:C16H15ClO2Pureza:99.88%Forma y color:SolidPeso molecular:274.74ITE
CAS:<p>ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.</p>Fórmula:C14H10N2O3SPureza:97.91% - 99.14%Forma y color:SolidPeso molecular:286.31CAY 10465
CAS:<p>CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).</p>Fórmula:C15H9Cl2F3Pureza:98.80%Forma y color:SolidPeso molecular:317.13StemRegenin 1
CAS:<p>StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.</p>Fórmula:C24H23N5OSPureza:98% - 99.89%Forma y color:SolidPeso molecular:429.54PDM2
CAS:<p>PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.</p>Fórmula:C14H9Cl3Pureza:99.44%Forma y color:SolidPeso molecular:283.58Skatole
CAS:<p>Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.</p>Fórmula:C9H9NPureza:99.74%Forma y color:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecular:131.17Brevifolincarboxylic acid
CAS:<p>Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.</p>Fórmula:C13H8O8Pureza:99.42% - 99.59%Forma y color:SolidPeso molecular:292.21,4-Chrysenequinone
CAS:<p>1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).</p>Fórmula:C18H10O2Pureza:99.07% - 99.84%Forma y color:SolidPeso molecular:258.27Pifithrin-α hydrobromide
CAS:<p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>Fórmula:C16H18N2OS·HBrPureza:97.71% - >99.99%Forma y color:SolidPeso molecular:367.3YL-109
CAS:<p>YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.</p>Fórmula:C14H11NO2SPureza:99.77% - ≥95%Forma y color:SolidPeso molecular:257.31DiMNF
CAS:<p>Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.</p>Fórmula:C21H16O4Pureza:97.60%Forma y color:SolidPeso molecular:332.35L-Kynurenine-d4
CAS:<p>L-Kynurenine-d4 is a deuterated isotope compound of L-Kynurenine. L-Kynurenine is a metabolite of tryptophan and an endogenous agonist of the AHR.</p>Fórmula:C10H8D4N2O3Forma y color:SolidPeso molecular:212.24D-Kynurenine
CAS:<p>D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.</p>Fórmula:C10H12N2O3Pureza:99.68%Forma y color:SolidPeso molecular:208.21Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Fórmula:C20H25Cl2FN4OSPureza:99.89%Forma y color:SolidPeso molecular:459.41Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Fórmula:C15H16Cl3N3O2Pureza:99.75% - 99.79%Forma y color:Colorless SolidPeso molecular:376.67CAY10464
CAS:<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Fórmula:C15H12Cl2OPureza:99.96%Forma y color:SolidPeso molecular:279.16
