Lipoxigenasa
Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.
Se han encontrado 124 productos de "Lipoxigenasa"
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Zileuton
CAS:<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Fórmula:C11H12N2O2SPureza:98.72% - 99.43%Forma y color:Crystalline SolidPeso molecular:236.29Meclofenoxate hydrochloride
CAS:<p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>Fórmula:C12H16ClNO3·HClPureza:97.05%Forma y color:White Crystal PowderPeso molecular:294.17Diethylcarbamazine citrate
CAS:<p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>Fórmula:C10H21N3O·C6H8O7Pureza:99.61%Forma y color:White Crystalline Powder And Animals (Epa 1998)Peso molecular:391.42mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Fórmula:C20H22N4O6SPeso molecular:446.12601Damnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Fórmula:C16H12O5Forma y color:SolidPeso molecular:284.267Lipoxygenase
CAS:<p>Lipoxygenase (LOX) is a dioxygenase that catalyzes the peroxidation of linoleic acid (LA) or arachidonic acid (AA) in the presence of molecular oxygen.</p>Forma y color:SolidCMI977
CAS:<p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>Fórmula:C16H19FN2O4Pureza:98%Forma y color:SolidPeso molecular:322.3315-LOX-1 inhibitor 1
CAS:<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Fórmula:C22H21ClN2O4Forma y color:SolidPeso molecular:412.875-LOX/NO-IN-1
<p>5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.</p>Fórmula:C22H18N6O4Forma y color:SolidPeso molecular:430.42DKI5
CAS:<p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>Fórmula:C8H10N4SPureza:98%Forma y color:SoildPeso molecular:194.26h15-LOX-2 inhibitor 2
<p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>Fórmula:C22H30Cl2N6O3Forma y color:SolidPeso molecular:497.42ThioLox
CAS:<p>ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.</p>Fórmula:C15H18N2OSPureza:99.98%Forma y color:SoildPeso molecular:274.38Ruthenoleuton
<p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>Fórmula:C13H16N2O2RuForma y color:SolidPeso molecular:333.35Aureusidin
CAS:<p>Aureusidin (Auresidin) shows antioxidant and lipoxygenase inhibitory activity with anti-inflammatory effects.</p>Fórmula:C15H10O6Pureza:98.17% - 99.18%Forma y color:SolidPeso molecular:286.24CJ-13,610 hydrochloride
CAS:<p>CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological</p>Fórmula:C22H24ClN3O2SPureza:98.5%Forma y color:SoildPeso molecular:429.96Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Fórmula:C13H16FeN2O2Forma y color:SolidPeso molecular:288.125-LOX-IN-5
<p>Compound 29, also known as 5-LOX-IN-5, is a 5-lipoxygenase (5-LOX) inhibitor with an inhibitory concentration 50 (IC50) of 56 nM, utilized in research</p>Fórmula:C19H18BrN3O2SPureza:98%Forma y color:SolidPeso molecular:432.33LOX-IN-5
CAS:<p>LOX-IN-5 (compound 22) is a non-selective LOX inhibitor.</p>Fórmula:C21H25FN4O2SForma y color:SolidPeso molecular:416.51(±)15-HEDE
CAS:<p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>Fórmula:C20H36O3Forma y color:SolidPeso molecular:324.50513-epi-12-oxo Phytodienoic Acid
CAS:<p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>Fórmula:C18H28O3Forma y color:SolidPeso molecular:292.41Myxochelin A
CAS:<p>Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.</p>Fórmula:C20H24N2O7Forma y color:SolidPeso molecular:404.4191-Naphthyl 3,5-dinitrobenzoate
CAS:<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Fórmula:C17H10N2O6Pureza:99.79%Forma y color:SolidPeso molecular:338.27(-)-Dihydroguaiaretic acid
<p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>Fórmula:C20H26O4Forma y color:SolidPeso molecular:330.424ZD-2138
CAS:<p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>Fórmula:C23H24FNO4Pureza:99.68% - >99.99%Forma y color:SolidPeso molecular:397.44Lagunamycin
CAS:<p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>Fórmula:C19H21N3O4Forma y color:SolidPeso molecular:355.392-Methyl-1-naphthol
CAS:<p>2-Methyl-1-naphthol is a prostaglandin G/H synthase and polyunsaturated fatty acid 5-lipoxygenase inhibitor, suitable for biochemical experiments.</p>Fórmula:C11H10OPureza:98.33%Forma y color:SolidPeso molecular:158.2KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Fórmula:C16H14N2SPureza:99.34%Forma y color:SolidPeso molecular:266.36E 6080 HCl
CAS:<p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>Fórmula:C17H20ClN3O3S2Pureza:99.80%Forma y color:SoildPeso molecular:413.945-Lipoxygenase-IN-3
CAS:<p>Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>Fórmula:C19H16ClN5OForma y color:SolidPeso molecular:365.82Caffeoylcalleryanin
CAS:<p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>Fórmula:C22H24O11Forma y color:SolidPeso molecular:464.4CBS-1114 HCl
CAS:<p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>Fórmula:C13H14ClN3Pureza:99.36%Forma y color:SoildPeso molecular:247.72Zileuton sodium
CAS:<p>Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase with anti-inflammatory activities.</p>Fórmula:C11H11N2NaO2SForma y color:SolidPeso molecular:258.27Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
CAS:<p>Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), 12/15-LO inhibitor for diabetes. Affordable Excellence: Reliable Quality You Can Trust</p>Fórmula:C19H15NO4Forma y color:SolidPeso molecular:321.33Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Fórmula:C9H10N2OPureza:97.24%Forma y color:White Solid Solid CrystallinePeso molecular:162.19Malotilate
CAS:<p>Malotilate (Kantec) is a medicine used for the therapy of liver cirrhosis.</p>Fórmula:C12H16O4S2Pureza:99.79% - 99.79%Forma y color:SolidPeso molecular:288.38SKF-86002
CAS:<p>SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).</p>Fórmula:C16H12FN3SPureza:98% - 99.85%Forma y color:SolidPeso molecular:297.35Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Fórmula:C18H18O4Pureza:99.88% - 99.91%Forma y color:SolidPeso molecular:298.33Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Fórmula:C9H8O4Pureza:98.89% - 99.3%Forma y color:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecular:180.164',5-Dihydroxyflavone
CAS:<p>4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).</p>Fórmula:C15H10O4Pureza:99.81%Forma y color:SolidPeso molecular:254.24BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Fórmula:C15H14ClN3OPureza:99.34%Forma y color:SolidPeso molecular:287.74PGS-IN-1
CAS:<p>PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).</p>Fórmula:C19H26O3Pureza:99.39%Forma y color:SolidPeso molecular:302.41Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Fórmula:C17H14O6Pureza:98.67% - 99.88%Forma y color:SolidPeso molecular:314.29Indirubin-3'-monoxime
CAS:<p>Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/</p>Fórmula:C16H11N3O2Pureza:99.55%Forma y color:Dark Red SolidPeso molecular:277.28S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Fórmula:C14H14O4Pureza:98.00% - ≥98%Forma y color:SolidPeso molecular:246.26LOX-IN-3 dihydrochloride
CAS:<p>LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).</p>Fórmula:C13H15Cl2FN2O2SPureza:99.96%Forma y color:SolidPeso molecular:353.24Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Fórmula:C20H16O5Pureza:98% - 99.61%Forma y color:SolidPeso molecular:336.34ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Fórmula:C12H13NO3Pureza:98.9%Forma y color:Off-White To Light Tan Crystalline PowderPeso molecular:219.24Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Fórmula:C18H22O4Pureza:97.82% - 99.91%Forma y color:SolidPeso molecular:302.36β-Aminopropionitrile hydrochloride
CAS:<p>β-Aminopropionitrile hydrochloride is a selective, oral, irreversible inhibitor of lysyl oxidase (LOX) that reduces metastatic seeding potential.</p>Fórmula:C3H7ClN2Pureza:99.32%Forma y color:SolidPeso molecular:106.55Xanthatin
CAS:<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>Fórmula:C15H18O3Pureza:98.48% - 99.96%Forma y color:SolidPeso molecular:246.3
