Lipoxigenasa
Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.
Se han encontrado 124 productos de "Lipoxigenasa"
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β-Boswellic acid
CAS:<p>β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic</p>Fórmula:C30H48O3Pureza:99.2% - 99.91%Forma y color:Off-White SolidPeso molecular:456.7ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE
CAS:<p>ETHYL 5-HYDROXY-2-METHYLINDOLE-3-CARBOXYLATE is useful for preparation and study of hypoxia-selective cytotoxicity of indolequinone antitumor agents.</p>Fórmula:C12H13NO3Pureza:98.9%Forma y color:Off-White To Light Tan Crystalline PowderPeso molecular:219.24BI-0115
CAS:<p>BI-0115 inhibits LOX-1, preventing oxLDL uptake by triggering receptor inhibition and dimer formation.</p>Fórmula:C15H14ClN3OPureza:99.34%Forma y color:SolidPeso molecular:287.74Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Fórmula:C17H14O6Pureza:98.67% - 99.88%Forma y color:SolidPeso molecular:314.29Caffeic Acid
CAS:<p>Caffeic acid is a dual inhibitor of 5-lipoxygenase and TRPV1 ion channels. High-Quality, Low-Cost!</p>Fórmula:C9H8O4Pureza:98.89% - 99.3%Forma y color:Yellow Crystals From Concentrated Aqueous Solutions Alkaline Solns Turn From Yellow To Orange Alkaline Solutions Turn From Yellow To Orange (Ntp 1992)Peso molecular:180.162,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Fórmula:C14H22O2Pureza:97.11%Forma y color:PelletslargecrystalsPeso molecular:222.32Tepoxalin
CAS:<p>Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.</p>Fórmula:C20H20ClN3O3Pureza:99.94%Forma y color:SolidPeso molecular:385.845-O-Demethylnobiletin
CAS:<p>5-O-Demethylnobiletin is a natural anti-inflammatory that inhibits 5-LOX without altering COX-2 expression.</p>Fórmula:C20H20O8Pureza:99.83% - ≥95%Forma y color:SolidPeso molecular:388.37FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Fórmula:C16H15N3OPureza:98.79%Forma y color:SolidPeso molecular:265.31ML351
CAS:<p>ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).</p>Fórmula:C15H11N3OPureza:97.67%Forma y color:SolidPeso molecular:249.27Linoleyl alcohol
CAS:<p>Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].</p>Fórmula:C18H34OPureza:98.12%Forma y color:SolidPeso molecular:266.463-Hydroxycoumarin
CAS:<p>3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitors</p>Fórmula:C9H6O3Pureza:99.5% - 99.77%Forma y color:SolidPeso molecular:162.14ML355
CAS:<p>ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.</p>Fórmula:C21H19N3O4S2Pureza:98.02% - 98.2%Forma y color:SolidPeso molecular:441.5211-Keto-β-boswellic acid
CAS:<p>11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.</p>Fórmula:C30H46O4Pureza:99.68%Forma y color:SolidPeso molecular:470.68Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Fórmula:C22H30O4Pureza:99.38%Forma y color:SolidPeso molecular:358.47Wedelolactone
CAS:<p>Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.</p>Fórmula:C16H10O7Pureza:98.07% - 99.87%Forma y color:SolidPeso molecular:314.25CAY10698
CAS:<p>CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).</p>Fórmula:C17H17N3O4S2Pureza:98.97%Forma y color:SolidPeso molecular:391.46U-73122
CAS:<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Fórmula:C29H40N2O3Pureza:97.50%Forma y color:Solid Off-WhitePeso molecular:464.645-LOX inhibitor
CAS:<p>5-LOX inhibitor (1-(sec-Butyl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one) is an itraconazole impurity, a LOX-5 inhibitor.</p>Fórmula:C22H27N5O2Pureza:98.01%Forma y color:SolidPeso molecular:393.48a-Boswellic Acid
CAS:Producto controlado<p>Applications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.<br>References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);<br></p>Fórmula:C30H48O3Forma y color:NeatPeso molecular:456.70Golocdacimab
CAS:<p>Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.</p>Pureza:95%Forma y color:Liquid4-(2-Methylpropyl)benzenemethanol
CAS:Producto controladoFórmula:C11H16OForma y color:NeatPeso molecular:164.24tHGA
CAS:<p>tHGA is a potent inhibitor of lipoxygenase.</p>Fórmula:C18H24O4Pureza:98%Forma y color:SolidPeso molecular:304.38BI-L 357
CAS:<p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>Fórmula:C18H18O4SForma y color:SolidPeso molecular:330.4L 652343
CAS:<p>L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.</p>Fórmula:C22H14F3NO2S2Forma y color:SolidPeso molecular:445.482-TEDC
CAS:<p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>Fórmula:C16H13NO4SPureza:99.75%Forma y color:SolidPeso molecular:315.34Atreleuton
CAS:<p>Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.</p>Fórmula:C16H15FN2O2SPureza:98%Forma y color:SolidPeso molecular:318.37RWJ 63556
CAS:<p>RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.</p>Fórmula:C11H10FNO3S2Pureza:99.92%Forma y color:SolidPeso molecular:287.33AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Fórmula:C30H33F2NO4Pureza:98%Forma y color:SolidPeso molecular:509.58PF-4191834
CAS:<p>PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.</p>Fórmula:C22H23N3O2SPureza:99.83% - 99.98%Forma y color:SolidPeso molecular:393.5Enazadrem
CAS:<p>Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.</p>Fórmula:C18H25N3OPureza:98%Forma y color:SolidPeso molecular:299.41Fluindione
CAS:<p>Fluindione is a hematologic drug.</p>Fórmula:C15H9FO2Forma y color:SolidPeso molecular:240.23LY 269415
CAS:<p>LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.</p>Fórmula:C19H28N2O2SForma y color:SolidPeso molecular:348.5YS-121
CAS:<p>YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>Fórmula:C20H26ClN3O2SForma y color:SolidPeso molecular:407.96Lipoxygenin
CAS:<p>Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.</p>Fórmula:C24H22N2O4Forma y color:SolidPeso molecular:402.44LP117
CAS:<p>LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).</p>Fórmula:C21H23ClN4O2SPureza:98%Forma y color:SolidPeso molecular:430.95ICI 211965
CAS:<p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>Fórmula:C24H23NO2SPureza:98%Forma y color:SolidPeso molecular:389.51Fenleuton
CAS:<p>Fenleuton is a 5-lipoxygenase inhibitor.</p>Fórmula:C17H15FN2O3Pureza:98%Forma y color:SolidPeso molecular:314.31LY 221068
CAS:<p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>Fórmula:C20H30N2O2SPureza:98%Forma y color:SolidPeso molecular:362.53L 656224
CAS:<p>L 656224 is a 5-LO inhibitor.</p>Fórmula:C20H21ClO3Pureza:98%Forma y color:SolidPeso molecular:344.83Texasin
CAS:<p>Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.</p>Fórmula:C16H12O5Pureza:98%Forma y color:SolidPeso molecular:284.26Cgp 8065
CAS:<p>Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.</p>Fórmula:C16H15N3O4S2Forma y color:SolidPeso molecular:377.44EP6
CAS:<p>EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.</p>Fórmula:C24H30N4OPureza:98%Forma y color:SolidPeso molecular:390.52HZ52
CAS:<p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>Fórmula:C24H26ClN3O2SForma y color:SolidPeso molecular:456RG 6866
CAS:<p>RG 6866 is a inhibitor of 5-lipoxygenase.</p>Fórmula:C16H17NO3Pureza:98%Forma y color:SolidPeso molecular:271.31L-651392
CAS:<p>L-651392 is an inhibitor of leukotriene.</p>Fórmula:C14H10BrNO3SForma y color:SolidPeso molecular:352.2MLS000536924
CAS:<p>MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.</p>Fórmula:C16H15N3SForma y color:SolidPeso molecular:281.38A-69412
CAS:<p>A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.</p>Fórmula:C7H10N2O3Pureza:99.54%Forma y color:SolidPeso molecular:170.17Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Fórmula:C18H28O2Pureza:99.95%Forma y color:SolidPeso molecular:276.41Butibufen
CAS:<p>Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.</p>Fórmula:C14H20O2Pureza:98.11% - 98.91%Forma y color:SolidPeso molecular:220.31
