Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Se han encontrado 940 productos de "Receptor 5-HT"
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ECPLA
CAS:<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Fórmula:C21H25N3OForma y color:SolidPeso molecular:335.44Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.41Quetiapine-d4 fumarate
CAS:<p>Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.</p>Fórmula:C25H29N3O6SPureza:98%Forma y color:SolidPeso molecular:503.61Mirtazapine N-oxide
CAS:<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Fórmula:C17H19N3OForma y color:SolidPeso molecular:281.359HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Fórmula:C35H43Cl2F2N5O4Forma y color:SolidPeso molecular:706.65GM-60186
<p>GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.</p>Fórmula:C30H33FN2O4Forma y color:SolidPeso molecular:504.591-Phenylbiguanide HCl
CAS:<p>Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.</p>Fórmula:C8H12ClN5Pureza:99.31%Forma y color:SolidPeso molecular:213.67Tegaserod
CAS:<p>Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).</p>Fórmula:C16H23N5OPureza:99.20% - 99.89%Forma y color:SolidPeso molecular:301.39Clothiapine
CAS:<p>Clothiapine is an atypical antipsychotic of the dibenzothiazepine chemical class.</p>Fórmula:C18H18ClN3SPureza:99.93%Forma y color:SolidPeso molecular:343.87Thioridazine
CAS:<p>Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.</p>Fórmula:C21H26N2S2Forma y color:SolidPeso molecular:370.57Altanserin
CAS:<p>Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.</p>Fórmula:C22H22FN3O2SForma y color:SolidPeso molecular:411.49Setiptiline maleate
CAS:<p>Setiptiline maleate is a norepinephrine reuptake inhibitor, 2-adrenergic receptor antagonist, H1 receptor inverse agonist, 5-HT serotonin receptor antagonist.</p>Fórmula:C23H23NO4Pureza:99.94%Forma y color:SolidPeso molecular:377.43SB-269970 hydrochloride
CAS:<p>SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivity</p>Fórmula:C18H28N2O3S·HClPureza:98.45%Forma y color:SolidPeso molecular:388.95Fluvoxamine
CAS:<p>Fluvoxamine (DU-23000) is a selective, orally available 5-HT and serotonin reuptake inhibitor (SSRI) exhibiting antidepressant effects.</p>Fórmula:C15H21F3N2O2Forma y color:SolidPeso molecular:318.33SB-277011 hydrochloride
CAS:<p>SB-277011 hydrochloride (SB-277011A hydrochloride) is a D3R antagonist, which induces delayed ejaculation in rats.</p>Fórmula:C28H31ClN4OPureza:98.54%Forma y color:SolidPeso molecular:475.03Cefaclor
CAS:<p>Cefaclor (Panoral) is a cephalosporin antibiotic.</p>Fórmula:C15H14ClN3O4SPureza:99.03% - 99.98%Forma y color:SolidPeso molecular:367.81Ziprasidone D8
CAS:<p>Ziprasidone D8, deuterium-labeled, is a potent antipsychotic, antagonizing 5-HT and dopamine receptors.</p>Fórmula:C21H21ClN4OSPureza:98%Forma y color:SolidPeso molecular:420.993-Hydroxy agomelatine
CAS:<p>3-Hydroxy agomelatine (3-Hydroxyagomelatine) is a 5-HT2C receptor antagonist used in the study of neurological disorders.</p>Fórmula:C15H17NO3Forma y color:SolidPeso molecular:259.3cis-(Z)-Flupentixol dihydrochloride
CAS:<p>cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.</p>Fórmula:C23H27Cl2F3N2OSPureza:98.07%Forma y color:SolidPeso molecular:507.44Agomelatine (L(+)-Tartaric acid)
CAS:<p>Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and</p>Fórmula:C19H23NO8Forma y color:SolidPeso molecular:393.39Granisetron
CAS:<p>Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.</p>Fórmula:C18H24N4OForma y color:SolidPeso molecular:312.41(R)-Praziquantel-d11
CAS:<p>(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel.</p>Fórmula:C19H24N2O2Pureza:98%Forma y color:SolidPeso molecular:323.47Olanzapine D3
CAS:<p>Olanzapine D3 is the deuterium labeled Olanzapine.</p>Fórmula:C17H20N4SPureza:98%Forma y color:SolidPeso molecular:315.45Eplivanserin (mixture)
CAS:<p>Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist,</p>Fórmula:C19H21FN2O2Forma y color:SolidPeso molecular:328.387Aripiprazole (D8)
CAS:<p>Aripiprazole D8 (OPC-14597 D8) is the deuterium-labeled Aripiprazole. Aripiprazole is a human 5-HT1A receptor partial agonist (Ki: 4.2 nM).</p>Fórmula:C23H27Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:456.44BW 723C86
CAS:<p>BW 723C86 is a 5-HT2B receptor agonist with anxiolytic effects, inducing overeating and reduced grooming in rats, useful in studying neurological disorders.</p>Fórmula:C16H19ClN2OSPureza:99.35%Forma y color:SolidPeso molecular:322.85SB-200646A
CAS:<p>SB-200646A: oral 5-HT2B/2C antagonist; higher affinity than 5-HT2A (pKi: 7.5, 6.9 vs 5.2); anxiolytic with in vivo effects.</p>Fórmula:C15H15ClN4OPureza:98%Forma y color:SolidPeso molecular:302.76Agomelatine-d6
CAS:<p>Agomelatine D6 (S-20098 D6) is a deuterium-labeled Agomelatine. Agomelatine is a specific agonist of MT1 and MT2 receptors.</p>Fórmula:C15H17NO2Pureza:98%Forma y color:SolidPeso molecular:249.34Quetiapine-d4 hemifumarate
CAS:<p>Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a agonist of 5-HT receptors and a antagonist of dopamine receptor,with ntidepressant and anxiolytic.</p>Fórmula:C25H29N3O6SPureza:98%Forma y color:White SolidPeso molecular:503.61Flibanserin-d4
CAS:<p>Flibanserin: Serotonin 5-HT1A agonist (Ki=1 nM), 5-HT2A antagonist (49 nM). Flibanserin D4 is deuterium-labeled.</p>Fórmula:C20H21F3N4OPureza:98%Forma y color:SolidPeso molecular:394.43Sumatriptan
CAS:<p>Sumatriptan (GR 43175 free base) is a 5-HT1 receptor agonist with anti-inflammatory activity used in acute migraine and acute myocardial infarction.</p>Fórmula:C14H21N3O2SPureza:99.93%Forma y color:White To Off-White Crystalline PowderPeso molecular:295.4Paliperidone Palmitate
CAS:<p>Paliperidone: atypical antipsychotic, dopamine & serotonin antagonist, affects α1/α2 adrenergic and H1 histamine receptors.</p>Fórmula:C39H57FN4O4Pureza:98%Forma y color:SolidPeso molecular:664.89Spiroxatrine
CAS:<p>Spiroxatrine (R 5188) is a 5-HT1α and α2-adrenergic dual antagonist with sedative activity for the study of diseases related to the cardiovascular system.</p>Fórmula:C22H25N3O3Pureza:99.94%Forma y color:SolidPeso molecular:379.45Clozapine-d8
CAS:<p>Clozapine-d8 is a deuterium-labeled analog of Clozapine, used as an internal standard for mass spectrometric analysis of this atypical antipsychotic.</p>Fórmula:C18H19ClN4Forma y color:SolidPeso molecular:334.87Dehydroaripiprazole
CAS:<p>Dehydroaripiprazole (DM-14857), aripiprazole's active metabolite, is formed by CYP3A4 and CYP2D6, with similar antipsychotic effects.</p>Fórmula:C23H25Cl2N3O2Pureza:98.7%Forma y color:SolidPeso molecular:446.37Asenapine hydrochloride
CAS:<p>Asenapine hydrochloride (Org 5222 hydrochloride) is an antagonist of 5-hydroxytryptamine, adrenergic, dopamine, and histamine receptors with antipsychotic effects.</p>Fórmula:C17H17Cl2NOForma y color:SolidPeso molecular:322.23Alosetron D3 Hydrochloride
CAS:<p>Alosetron D3 (GR 68755 D3) Hydrochloride is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Fórmula:C17H19ClN4OPureza:98%Forma y color:SolidPeso molecular:333.83Nefazodone
CAS:<p>Nefazodone (Nefadar) is an oral antidepressant that is an antagonist of postsynaptic 5-HT 2A receptors and 5-HT 2C receptors, and SNDRI.</p>Fórmula:C25H32ClN5O2Pureza:99.85%Forma y color:White To Off-White Crystalline PowderPeso molecular:470.01Cariprazine D6
CAS:<p>Cariprazine D6 (RGH-188 D6) is a deuterium-labeled Cariprazine. Cariprazine is an antipsychotic agent (D3 receptors, Ki: 0.085 nM; D2 receptors, Ki: 0.49 nM).</p>Fórmula:C21H26D6Cl2N4OPureza:98%Forma y color:SolidPeso molecular:433.45Ziprasidone amino acid
CAS:<p>Ziprasidone Impurity C is a byproduct of Ziprasidone, an antipsychotic that blocks 5-HT and dopamine receptors.</p>Fórmula:C21H23ClN4O2SForma y color:SolidPeso molecular:430.95Levomepromazine
CAS:<p>Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.</p>Fórmula:C19H24N2OSPureza:99.15%Forma y color:SolidPeso molecular:328.47Vilazodone-d8
CAS:<p>Vilazodone D8 is a deuterium-labeled vilazodone. Vilazodone is a combined inhibitor of serotonin specific reuptake (SSRI) and agonist of 5-HT1A receptor partial.</p>Fórmula:C26H27N5O2Pureza:98%Forma y color:SolidPeso molecular:449.573-Hydroxy agomelatine D3
CAS:<p>3-Hydroxy agomelatine D3 is a deuterated metabolite of Agomelatine and a 5-HT2C antagonist (IC50: 3.2 μM, Ki: 1.8 μM).</p>Fórmula:C15H17NO3Pureza:98%Forma y color:SolidPeso molecular:262.325-HT2B antagonist-1
CAS:<p>Orally active 5-HT2B antagonist; IC50 = 33.4 nM; potential for hepatocellular, cardiovascular, GI disease research.</p>Fórmula:C11H14BrN5Pureza:99.965%Forma y color:SolidPeso molecular:296.17Asenapine
CAS:<p>Asenapine (Org 5222) is a 5-HT receptor, adrenergic receptor, and histamine receptor antagonist with antipsychotic properties for the treatment of schizophrenia</p>Fórmula:C17H16ClNOPureza:99.64%Forma y color:CoaPeso molecular:285.775-HT3 antagonist 5
CAS:<p>5-HT3 antagonist 5, a quinoxalin-2-carboxamide, blocks 5-HT3 receptors and has antidepressant effects in mice.</p>Fórmula:C16H13N3O2Pureza:99.84%Forma y color:SolidPeso molecular:279.294,4-Diphenylbutylamine hydrochloride
CAS:<p>4,4-Diphenylbutylamine shows affinity for the 5-HT2A and H1 receptors with Kis of 2589 and 1670 nM, respectively[1].</p>Fórmula:C16H20ClNForma y color:SolidPeso molecular:261.79WAY-100635
CAS:<p>WAY-100635 is a potent 5-HT 1A receptor antagonist pyramidal neuron firing frequency during conditioned reflexes; a dopamine D4 receptor agonist .</p>Fórmula:C25H34N4O2Pureza:98.972%Forma y color:SolidPeso molecular:422.56LY310762
CAS:<p>LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM.</p>Fórmula:C24H27FN2O2·HClPureza:99.8%Forma y color:SolidPeso molecular:430.94Melperone
CAS:<p>Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.</p>Fórmula:C16H22FNOPureza:98.84%Forma y color:SolidPeso molecular:263.35
