LRRK2

MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous …

BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).

EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.

CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 …

LRRK2 inhibitor 1 is a selective, potent and oral LRRK2 inhibitor with an pIC50 of …

IKK-16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex …

CZC-25146 is an effective, specific and metabolically stable LRRK2 inhibitor with IC50 of 4.76/6.87 nM …

CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.

PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3/11 nM …

PF-06454589 is a potent inhibitor of LRRK2.

CZC-54252 is a potent inhibitor of LRRK2.

GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).

GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.

HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).

CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type …

GNE-0877 is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 …

URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and …

JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, …

LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.

PFE-360 is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).

GSK2578215A is a potent and selective LRRK2 kinase inhibitor.