Inhibidores de ciclooxigenasa (COX)
Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.
Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"
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Tebufelone
CAS:<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Fórmula:C20H28O2Pureza:99.32%Forma y color:SolidPeso molecular:300.44Vedaprofen
CAS:<p>Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.</p>Fórmula:C19H22O2Pureza:99.24% - 99.70%Forma y color:SolidPeso molecular:282.38COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Fórmula:C22H24N2O2SPureza:98%Forma y color:SolidPeso molecular:380.5COX-2/NLRP3-IN-1
<p>COX-2/NLRP3-IN-1 (Compound 6k) is an inhibitor that targets COX-2 and NLRP3, exhibiting an IC50 value of 1.53 μM for COX-2. This compound exerts anti-inflammatory effects by inhibiting the NF-κB/NLRP3 signaling pathway.</p>Fórmula:C24H19Cl2N5OSPeso molecular:495.06874Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Fórmula:C19H14ClNO4Peso molecular:355.06114Akt/NF-κB/MAPK-IN-1
<p>Akt/NF-κB/MAPK-IN-1 (compound 2m) serves as a potent, orally active inhibitor targeting NO with an IC50 of 7.70 μM and demonstrates low toxicity.</p>Fórmula:C38H56N2O4Pureza:98%Forma y color:SolidPeso molecular:604.86Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Fórmula:C24H22N2O4SPureza:98%Forma y color:SolidPeso molecular:434.51Lonazolac Calcium
CAS:<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Fórmula:C34H24CaCl2N4O4Pureza:98%Forma y color:SolidPeso molecular:663.56COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Fórmula:C22H19NO2S2Pureza:98%Forma y color:SolidPeso molecular:393.52Cafestol palmitate
CAS:<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Fórmula:C36H58O4Forma y color:SolidPeso molecular:554.843Amfenac sodium
CAS:<p>Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.</p>Fórmula:C15H12NNaO3Pureza:98%Forma y color:SolidPeso molecular:277.26Bermoprofen
CAS:<p>Bermoprofen (AD-1590) is an anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.</p>Fórmula:C18H16O4Pureza:98.72% - 99.28%Forma y color:SolidPeso molecular:296.32Feladilimab
CAS:<p>Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98%Forma y color:LiquidPeso molecular:145.24 kDaAnti-inflammatory agent 93
<p>Compound 2g (Anti-inflammatory agent 93) is an active compound that exhibits analgesic activity.</p>Fórmula:C27H17Cl2N3O2Forma y color:SolidPeso molecular:486.35Guaiacol-d3
CAS:<p>Guaiacol-d3 is a deuterated form of Guaiacol, which is a phenolic compound known for its ability to inhibit COX-2 expression and NF-κB activation in response to LPS stimulation, exhibiting anti-inflammatory properties.</p>Fórmula:C7H8O2Forma y color:SolidPeso molecular:127.16Flunixin
CAS:<p>Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), antipyretic, and analgesic used in pigs, horses, and cattle.</p>Fórmula:C14H11F3N2O2Forma y color:SolidPeso molecular:296.24Antiviral agent 61
<p>Antiviralagent 61 (compound Z40) serves as an effective antiviral agent with activity against Tomato Spotted Wilt Virus (TSWV), exhibiting an EC50 value of 252 µg/mL. It increases the RNA expression of Ndufb9, COX6B, 7.1.2.2, E, COX5B, Ndufs4, and SDHB, while reducing the expression of Ndufb7, Ndufa5, and G.</p>Fórmula:C22H23N5O4SForma y color:SolidPeso molecular:453.51Deracoxib
CAS:Fórmula:C17H14F3N3O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Brown powder to crystalPeso molecular:397.37Loxoprofen Sodium Salt Dihydrate
CAS:Fórmula:C15H17NaO3·2H2OPureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:304.32Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
CAS:Fórmula:C18H18F3NO2Pureza:>98.0%(HPLC)(N)Forma y color:Colorless to Yellow clear liquidPeso molecular:337.34DL-Lysine Acetylsalicylate
CAS:Fórmula:C9H8O4·C6H14N2O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:326.35SC-560
CAS:Fórmula:C17H12ClF3N2OPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:352.74Piroxicam D3
CAS:<p>Piroxicam D3 is deuterium labeled Piroxicam. Piroxicam is a COX inhibitor(human monocyte COX-1 and COX-2 with IC50s of 47, 25 μM , respectively) .</p>Fórmula:C15H13N3O4SPureza:98%Forma y color:SolidPeso molecular:334.37Parecoxib sodium
CAS:<p>Parecoxib: COX2 inhibitor, treats short-term postoperative pain, water-soluble, injectable, valdecoxib prodrug, less GI toxicity than ketorolac.</p>Fórmula:C19H18N2NaO4SPureza:98%Forma y color:SolidPeso molecular:393.41Fenbufen
CAS:Fórmula:C16H14O3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:254.29Rebamipide-d4
CAS:<p>Rebamipide D4 is deuterium labeled Rebamipide.</p>Fórmula:C19H15ClN2O4Pureza:98%Forma y color:SolidPeso molecular:374.81Rontalizumab
CAS:<p>Rontalizumab (RhuMab IFNalpha) is a humanized monoclonal antibody that neutralizes IFNalpha, used in the research of systemic lupus erythematosus.</p>Pureza:96.87% (SEC-HPLC) - 97.73% (SEC-HPLC)Forma y color:LiquidSuprofen
CAS:Fórmula:C14H12O3SPureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:260.31NS-398
CAS:Fórmula:C13H18N2O5SPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:314.36Tenoxicam
CAS:Fórmula:C13H11N3O4S2Pureza:>98.0%(HPLC)(N)Forma y color:White to Yellow to Green powder to crystalPeso molecular:337.37Tolmetin
CAS:Fórmula:C15H15NO3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:257.29Etoricoxib-d4
CAS:<p>Etoricoxib-d4 is the 2H-labeled form of Etoricoxib. Etoricoxib is a COX-2 inhibitor with antipyretic, analgesic, and potential anticancer properties.</p>Fórmula:C18H11D4ClN2O2SPureza:>99.99%Forma y color:SolidPeso molecular:362.87Ketorolac Tromethamine
CAS:Fórmula:C15H13NO3·C4H11NO3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:376.41Ibuprofen Impurity F
CAS:<p>Ibuprofen Impurity F, anti-inflammatory, inhibits COX-1 and COX-2 with IC50 of 13 μM and 370 μM.</p>Fórmula:C13H18O2Forma y color:SolidPeso molecular:206.28Parecoxib Sodium
CAS:Fórmula:C19H17N2NaO4SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:392.40Tryptanthrin
CAS:Fórmula:C15H8N2O2Pureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:248.24Valeroyl Salicylate
CAS:<p>Valeroyl Salicylate is a NSAID that extends lifespan, boosts mobility with age, and enhances stress resilience.</p>Fórmula:C12H14O4Pureza:97.512%Forma y color:SolidPeso molecular:222.24Ibuprofen Impurity K
CAS:<p>Ibuprofen Impurity K, an Ibuprofen contaminate; targeting COX-1 (IC50: 13 μM) & COX-2 (IC50: 370 μM).</p>Fórmula:C10H10O3Forma y color:SolidPeso molecular:178.18Oxaprozin
CAS:Fórmula:C18H15NO3Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:293.32Etofenamate
CAS:Fórmula:C18H18F3NO4Pureza:>98.0%(GC)(T)Forma y color:Colorless to Yellow clear liquidPeso molecular:369.34Etoricoxib
CAS:Fórmula:C18H15ClN2O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:358.84Floctafenine
CAS:<p>Floctafenine (R-4318) is a non-steroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor with analgesic activity for the study of pain.</p>Fórmula:C20H17F3N2O4Pureza:97.73%Forma y color:SolidPeso molecular:406.36Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76Xanthomicrol
CAS:<p>Xanthomicrol is a useful organic compound for research related to life sciences. The catalog number is T125642 and the CAS number is 16545-23-6.</p>Fórmula:C18H16O7Forma y color:SolidPeso molecular:344.319(S)-(+)-Ibuprofen D3
CAS:<p>(S)-(+)-Ibuprofen D3, deuterium-labeled S-enantiomer, COX-1/2 inhibitor with IC50s of 2.1 and 1.6 μM.</p>Fórmula:C13H18O2Pureza:98%Forma y color:SolidPeso molecular:209.3Loxoprofen sodium
CAS:<p>Loxoprofen sodium is a COX-1/COX-2 inhibitor (IC50: 6.5/13.5 μM) used orally for anti-inflammatory and antitumor effects.</p>Fórmula:C15H17NaO3Pureza:99.88%Forma y color:SolidPeso molecular:268.2834Bardoxolone Methyl
CAS:Fórmula:C32H43NO4Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:505.70Valdecoxib
CAS:Fórmula:C16H14N2O3SPureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:314.362-(6-Methoxynaphthalen-2-yl)acetic Acid
CAS:Fórmula:C13H12O3Pureza:>95.0%(GC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:216.24Licofelone
CAS:Fórmula:C23H22ClNO2Pureza:>95.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:379.88
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