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Inhibidores de ciclooxigenasa (COX)

Inhibidores de ciclooxigenasa (COX)

Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.

Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"

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  • LY 25648

    CAS:
    <p>LY 25648 is an antagonist of leukotriene B4.</p>
    Fórmula:C19H27NO2S
    Forma y color:Solid
    Peso molecular:333.49
  • ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Fórmula:C13H13ClN2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:296.77
  • LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Fórmula:C13H14N2
    Forma y color:Solid
    Peso molecular:198.26
  • PC407-ws

    CAS:
    <p>PC407-ws is a water-soluble novel COX-2 inhibitor.</p>
    Fórmula:C24H18F3N3Na2O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:563.46
  • Isonixin

    CAS:
    <p>Isonixin is used for the treatment of inflammation and pain associated with musculoskeletal and joint disorders.</p>
    Fórmula:C14H14N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:242.27
  • Prostaglandin G/H synthase 1 inhibitor

    CAS:
    <p>Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.</p>
    Fórmula:C13H11ClN2O
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:246.69
  • Tenosal

    CAS:
    <p>Tenosal obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid, and with analgesic and antipyretic properties, anti-inflammatory.</p>
    Fórmula:C12H8O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:248.25
  • LY 178002

    CAS:
    <p>LY 178002 inhibits 5-LPO (IC50: 0.6 μM), PLA2, and LTB4 production; weak on cyclooxygenase.</p>
    Fórmula:C18H25NO2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.46
  • L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Fórmula:C19H14Cl3NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:426.68
  • Eicosatetraynoic acid

    CAS:
    <p>ETYA activates PPARα/γ at 10μM, inhibits cyclooxygenase (ID50=8μM) and lipoxygenase (ID50=4μM).</p>
    Fórmula:C20H24O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:296.4
  • COX-2-IN-20

    CAS:
    <p>COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].</p>
    Fórmula:C11H9ClFN3O2
    Forma y color:Solid
    Peso molecular:269.66
  • Feprazone

    CAS:
    <p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>
    Fórmula:C20H20N2O2
    Pureza:99.6% - 99.89%
    Forma y color:Solid
    Peso molecular:320.39
  • Tilmacoxib

    CAS:
    <p>Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay).</p>
    Fórmula:C16H19FN2O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:338.4
  • COX-2-IN-1

    CAS:
    <p>COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).</p>
    Fórmula:C18H14ClF3N4O2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:442.84
  • Carpro-AM1

    CAS:
    <p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>
    Fórmula:C21H18ClN3O
    Forma y color:Solid
    Peso molecular:363.84
  • Enflicoxib

    CAS:
    <p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>
    Fórmula:C16H12F5N3O2S
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:405.34
  • Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Fórmula:C21H23N7OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:421.52
  • SC58451

    CAS:
    <p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>
    Fórmula:C20H19FO2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:342.43
  • COX-2-IN-21

    CAS:
    <p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>
    Fórmula:C21H22N6O4
    Forma y color:Solid
    Peso molecular:422.44
  • APHS

    CAS:
    <p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>
    Fórmula:C15H18O2S
    Forma y color:Solid
    Peso molecular:262.37