CAMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are specialized compounds that inhibit the activity of CaMK, a critical kinase involved in a range of cellular processes, particularly within the nervous system. CaMK is essential for translating calcium signals into various cellular responses, including synaptic plasticity, memory formation, and gene expression. Dysregulation of CaMK activity is linked to several neurological disorders, making these inhibitors valuable tools in the study of synaptic signaling, learning, and memory. By using CaMK inhibitors, researchers can explore the molecular mechanisms underlying cognitive function and synaptic plasticity. At CymitQuimica, we provide high-quality CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Se han encontrado 73 productos de "CAMK"
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CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Fórmula:C70H105F3N14O15SForma y color:SolidPeso molecular:1471.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Fórmula:C105H189N31O26SPureza:96.7%Forma y color:SolidPeso molecular:2333.88Calmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Forma y color:SolidPeso molecular:5301.1MLCK Peptide
CAS:MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Fórmula:C91H156N36O20Forma y color:SolidPeso molecular:2074.44Purine riboside triphosphate
CAS:Purine riboside triphosphate resembles adenosine; inhibits cancer cell growth by blocking RNA/DNA synthesis.Fórmula:C10H15N4O13P3Forma y color:SolidPeso molecular:492.17Purine riboside-5'-O-triphosphate sodium
CAS:Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Fórmula:C10H11N4Na4O13P3Forma y color:SolidPeso molecular:580.09RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Forma y color:Odour SolidCAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Forma y color:Lyophilized PowderPeso molecular:79 kDa (predicted); 100 kDa (reducing conditions)KN-62
CAS:KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Fórmula:C38H35N5O6S2Pureza:99.80% - >99.99%Forma y color:White SolidPeso molecular:721.84Ref: TM-T2694
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg207,00€50mg404,00€100mg592,00€1mL*10mM (DMSO)105,00€CALP2 acetate(261969-04-4 free base)
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.Fórmula:C68H104N14O13SPureza:97.43%Forma y color:SolidPeso molecular:1357.7Syntide 2 acetate(108334-68-5 free base)
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).Fórmula:C70H126N20O20Pureza:99.74%Forma y color:SolidPeso molecular:1567.85Autocamtide-2-related inhibitory peptide
CAS:Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Fórmula:C64H116N22O19Pureza:>99.99%Forma y color:SolidPeso molecular:1497.74Autocamtide 2 TFA(129198-88-5 free base)
Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.Fórmula:C67H119F3N22O22Pureza:98%Forma y color:SolidPeso molecular:1641.79CaMKP Inhibitor
CAS:<p>CaMKP Inhibitor can inhibit CaMKP.</p>Fórmula:C10H8NNaO7S2Pureza:96.55% - 99.98%Forma y color:SolidPeso molecular:341.28GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Fórmula:C18H19N5Pureza:98.87%Forma y color:SolidPeso molecular:305.38Ref: TM-T24111
1mg66,00€5mg120,00€10mg175,00€25mg295,00€50mg429,00€100mg605,00€1mL*10mM (DMSO)135,00€IGS-1.76
CAS:IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Fórmula:C22H18N2OSPureza:98.18% - 98.56%Forma y color:SolidPeso molecular:358.46KN-92
CAS:KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Fórmula:C24H25ClN2O3SForma y color:SolidPeso molecular:456.98KN-93
CAS:KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Fórmula:C26H29ClN2O4SPureza:99.56% - 99.86%Forma y color:White SolidPeso molecular:501.04Ref: TM-T2697
1mg54,00€2mg74,00€5mg107,00€10mg146,00€25mg289,00€50mg358,00€100mg523,00€1mL*10mM (DMSO)120,00€Trifluoperazine
CAS:Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Fórmula:C21H24F3N3SPureza:98.3% - 99.46%Forma y color:White To Yellowish Crystalline PowderPeso molecular:407.5NH125
CAS:NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Fórmula:C27H45IN2Pureza:98.60%Forma y color:SolidPeso molecular:524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€
