
CAMK
Calcium/Calmodulin-Dependent Protein Kinase (CaMK) inhibitors are specialized compounds that inhibit the activity of CaMK, a critical kinase involved in a range of cellular processes, particularly within the nervous system. CaMK is essential for translating calcium signals into various cellular responses, including synaptic plasticity, memory formation, and gene expression. Dysregulation of CaMK activity is linked to several neurological disorders, making these inhibitors valuable tools in the study of synaptic signaling, learning, and memory. By using CaMK inhibitors, researchers can explore the molecular mechanisms underlying cognitive function and synaptic plasticity. At CymitQuimica, we provide high-quality CaMK inhibitors to support your research in synaptic plasticity, cognitive function, and neuropharmacology.
Se han encontrado 69 productos de "CAMK"
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KN-62
CAS:<p>KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.</p>Fórmula:C38H35N5O6S2Pureza:99.80% - >99.99%Forma y color:White SolidPeso molecular:721.84CaMKP Inhibitor
CAS:<p>CaMKP Inhibitor can inhibit CaMKP.</p>Fórmula:C10H8NNaO7S2Pureza:96.55% - 99.98%Forma y color:SolidPeso molecular:341.28IGS-1.76
CAS:<p>IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.</p>Fórmula:C22H18N2OSPureza:98.18% - 98.56%Forma y color:SolidPeso molecular:358.46GSK3i XIII
CAS:<p>GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.</p>Fórmula:C18H19N5Pureza:98.87%Forma y color:SolidPeso molecular:305.38CALP2 acetate(261969-04-4 free base)
<p>CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.</p>Fórmula:C68H104N14O13SPureza:97.43%Forma y color:SolidPeso molecular:1357.7L-6355
CAS:<p>L-6355 is an agent of bioactive chemicals.</p>Fórmula:C25H30INO3Forma y color:SolidPeso molecular:519.42CK59
CAS:<p>CK59 inhibits CaMKII and several voltage-gated calcium channels, with an IC50 of ~50 μM.</p>Fórmula:C21H37N7O3Pureza:98%Forma y color:SolidPeso molecular:435.56W-5 hydrochloride
CAS:<p>W-5 hydrochloride (N-(6-Aminohexyl)-1-naphthalenesulfonamide HCl) is a potent calmodulin antagonist.</p>Fórmula:C16H23ClN2O2SPureza:99.35%Forma y color:Off-White Crystalline SolidPeso molecular:342.88Bisindolylmaleimide VII
CAS:<p>Bisindolylmaleimide VII is a selective inhibitor of protein kinase C.</p>Fórmula:C27H27N5O2Forma y color:SolidPeso molecular:453.54TIM-063
CAS:<p>TIM-063: ATP-competitive CaMKKα/β inhibitor, cell-permeable, Ki: 0.35/0.2 μM, IC50: 0.63/0.96 μM.</p>Fórmula:C18H9N3O4Forma y color:SolidPeso molecular:331.28CBP501
CAS:<p>CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.</p>Fórmula:C86H122F5N29O17Forma y color:SolidPeso molecular:1929.06Ph-HTBA
CAS:<p>Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.</p>Fórmula:C19H18O3Forma y color:SolidPeso molecular:294.34A-7 hydrochloride
CAS:<p>A-7 hydrochloride is a calmodulin antagonist and causes alterations in the subpopulation of CD44+CD24- in MDA-MB-231 cells.</p>Fórmula:C20H30Cl2N2O2SPureza:99.38%Forma y color:SolidPeso molecular:433.44RU 45144
CAS:<p>RU 45144 is an estradiol derivative with antiestrogenic activity.</p>Fórmula:C28H37NO3Pureza:98%Forma y color:SolidPeso molecular:435.6HOCPCA
CAS:<p>HOCPCA: potent, selective GHB site ligand; 27x higher affinity than GHB; crosses blood-brain barrier.</p>Fórmula:C6H8O3Pureza:98%Forma y color:SolidPeso molecular:128.13W-13 hydrochloride
CAS:<p>W-13 hydrochloride (W-13 HCl) is a calmodulin antagonist.</p>Fórmula:C14H18Cl2N2O2SPureza:98.51%Forma y color:White PowderPeso molecular:349.28Prenylamine lactate
CAS:<p>Prenylamine lactate, an ex-angina drug, depletes heart catecholamines and blocks calcium channels.</p>Fórmula:C27H33NO3Pureza:98%Forma y color:SolidPeso molecular:419.56Zaldaride maleate
CAS:<p>Zaldaride maleate blocks Ca2+, Na+, K+ currents, and nAChR; inhibits CaM cAMP PDE (IC50: 3.3 nM) and estrogen signaling.</p>Fórmula:C30H32N4O6Pureza:98%Forma y color:SolidPeso molecular:544.6TX-1123
CAS:<p>TX-1123: PTK/COX inhibitor, Src/eEF2-K/PKA/EGFR-K/PKC targeted, IC50 of 1.16μM(COX2), 15.7μM(COX1), low mitochondrial toxicity.</p>Fórmula:C20H24O3Forma y color:SolidPeso molecular:312.4CV-159
CAS:<p>CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action.</p>Fórmula:C31H34N4O7Pureza:98%Forma y color:SolidPeso molecular:574.62
