GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 266 productos para "GluR".
Filtrar por
Porcentaje de pureza
0
100
|
0
|
50
|
90
|
95
|
100
- Precio más bajo
- Precio más alto
- Pureza más baja
- Pureza más alta
- Entrega estimada más rápida
AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Fórmula:C25H28F3N5O6SPureza:99.19%Forma y color:SolidPeso molecular:583.58NBQX disodium
CAS:NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.Fórmula:C12H6N4Na2O6SPureza:97.32% - 97.60%Forma y color:Brown SolidPeso molecular:380.2415Piracetam
CAS:Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.Fórmula:C6H10N2O2Pureza:97.16% - 99.98%Forma y color:SolidPeso molecular:142.1558Basimglurant
CAS:Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).Fórmula:C18H13ClFN3Pureza:98.35%Forma y color:SolidPeso molecular:325.767γ-DGG acetate
CAS:gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.Fórmula:C9H16N2O7Pureza:99.92%Forma y color:SolidPeso molecular:264.2325Org-26576
CAS:Org-26576 is a positive allosteric modulator of the AMPA receptor.Fórmula:C11H12N2O2Pureza:99.67%Forma y color:White SolidPeso molecular:204.23LY339434 HCl
LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)Fórmula:C18H20ClNO4Pureza:97.10% - 97.19%Forma y color:SoildPeso molecular:349.81Decoglurant
CAS:Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.Fórmula:C21H11F6N5Pureza:99.77%Forma y color:SolidPeso molecular:447.336(R)-3,4-DCPG HCl
(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatalFórmula:C10H10ClNO6Pureza:99.74% - 99.83%Forma y color:SolidPeso molecular:275.64DHPG
CAS:DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.Fórmula:C8H10ClNO4Pureza:99.55% - 99.59%Forma y color:SolidPeso molecular:219.622ML353
ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.Fórmula:C19H15FN2OPureza:99.98% - 99.98%Forma y color:SolidPeso molecular:306.33KM02894
CAS:KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.Fórmula:C7H9N3OS2Pureza:99.98%Forma y color:SolidPeso molecular:215.296VU0483605
CAS:VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.Fórmula:C20H10Cl3N3O3Pureza:99.61%Forma y color:SolidPeso molecular:446.67(R)-ADX-47273
CAS:(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).Fórmula:C20H17F2N3O2Pureza:99.87%Forma y color:SolidPeso molecular:369.3647mGluR1 activator-1
mGluR1activator-1 is a stable vitamin K analog and mGluR1 activator capable of crossing the blood-brain barrier. It strongly activates transcription through steroid and xenobiotic receptors and retinoic acid receptors, effectively inducing neurogenesis in neural progenitor cells in mice. mGluR1activator-1 is applicable in studying neurodegenerative diseases, such as Alzheimer's.Forma y color:Odour SolidMMPIP hydrochloride
CAS:MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.Fórmula:C19H16ClN3O3Pureza:99.88%Forma y color:Yellow SolidPeso molecular:369.8GYKI-47261 dihydrochloride
CAS:GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Forma y color:White SolidPeso molecular:395.71(S,S)-BMS-984923
CAS:(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Fórmula:C22H15ClN2O2Forma y color:SolidPeso molecular:374.82MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Fórmula:C8H8FNO5Forma y color:SolidPeso molecular:217.15(S)-3,4-DCPG
CAS:(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Fórmula:C10H9NO6Pureza:98%Forma y color:SolidPeso molecular:239.18
