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GluR

GluR

Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.

Se han encontrado 265 productos de "GluR"

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productos por página.
  • LY487379

    CAS:
    LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).
    Fórmula:C21H19F3N2O4S
    Forma y color:Solid
    Peso molecular:452.45

    Ref: TM-T62756

    2mg
    46,00€
  • EGLU

    CAS:
    EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.
    Fórmula:C7H13NO4
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:175.18

    Ref: TM-T11165

    1mg
    264,00€
    2mg
    393,00€
    5mg
    650,00€
    10mg
    888,00€
    25mg
    1.369,00€
    50mg
    1.783,00€
  • γ-DGG

    CAS:
    gamma-DGG is a competitive blocker of AMPA receptor.
    Fórmula:C7H12N2O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:204.18

    Ref: TM-T15369

    5mg
    44,00€
    10mg
    57,00€
  • AMN082

    CAS:
    AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.
    Fórmula:C28H30Cl2N2
    Pureza:97.13% - 98.63%
    Forma y color:Solid
    Peso molecular:465.46

    Ref: TM-T21935

    1mg
    39,00€
    5mg
    73,00€
    10mg
    105,00€
    25mg
    205,00€
  • GYKI 53655 hydrochloride

    CAS:
    GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.
    Fórmula:C19H21ClN4O3
    Pureza:98.02%
    Forma y color:Solid
    Peso molecular:388.85

    Ref: TM-T15456

    1mg
    55,00€
  • LY341495

    CAS:
    LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.
    Fórmula:C20H19NO5
    Pureza:98.53% - 99.37%
    Forma y color:Solid
    Peso molecular:353.37

    Ref: TM-T15816

    5mg
    A consultar
    1mg
    39,00€
    1mL*10mM (DMSO)
    180,00€
  • VU0364770 hydrochloride

    CAS:
    VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).
    Fórmula:C12H10Cl2N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:269.13

    Ref: TM-T13317

    2mg
    34,00€
    5mg
    49,00€
    1mL*10mM (DMSO)
    110,00€
  • VU0422288

    CAS:
    VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.
    Fórmula:C17H11Cl2N3O2
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:360.19

    Ref: TM-T29135

    5mg
    75,00€
    10mg
    114,00€
    25mg
    222,00€
    50mg
    356,00€
    100mg
    580,00€
    500mg
    1.198,00€
  • Ro 01-6128

    CAS:
    Positive allosteric modulator of mGlu1 receptors
    Fórmula:C17H17NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:283.32

    Ref: TM-T23238

    2mg
    63,00€
  • JNJ-46778212

    CAS:
    JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.
    Fórmula:C20H17FN2O3
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:352.36

    Ref: TM-T15619

    5mg
    38,00€
    1mL*10mM (DMSO)
    42,00€
    10mg
    62,00€
    25mg
    119,00€
    50mg
    197,00€
    100mg
    314,00€
  • CFMTI

    CAS:
    CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.
    Fórmula:C19H16FN5O
    Pureza:97.23%
    Forma y color:Solid
    Peso molecular:349.36

    Ref: TM-T3482

    1mg
    57,00€
    2mg
    82,00€
    5mg
    120,00€
    1mL*10mM (DMSO)
    133,00€
    10mg
    170,00€
    25mg
    304,00€
    50mg
    432,00€
    100mg
    602,00€
  • (S)-ATPO

    CAS:

    (S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.

    Fórmula:C11H19N2O7P
    Pureza:98.37% - 99.41%
    Forma y color:Solid
    Peso molecular:322.25

    Ref: TM-T3473

    1mg
    52,00€
    2mg
    74,00€
    5mg
    97,00€
    10mg
    157,00€
    25mg
    285,00€
    50mg
    447,00€
    100mg
    653,00€
  • MTEP

    CAS:
    MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.
    Fórmula:C11H8N2S
    Forma y color:Solid
    Peso molecular:200.26

    Ref: TM-T73568

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Ro0711401

    CAS:
    Ro0711401 is an agonist of mGlu1 receptor.
    Fórmula:C18H11F3N2O3
    Pureza:97.57%
    Forma y color:Solid
    Peso molecular:360.29

    Ref: TM-T9021

    2mg
    34,00€
    5mg
    49,00€
    1mL*10mM (DMSO)
    50,00€
    10mg
    75,00€
    25mg
    145,00€
    50mg
    225,00€
    100mg
    371,00€
  • DNQX

    CAS:

    DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

    Fórmula:C8H4N4O6
    Pureza:97.27% - 99.1%
    Forma y color:Off-White Powder With A Yellow Tinge
    Peso molecular:252.14

    Ref: TM-T7304

    25mg
    56,00€
    50mg
    89,00€
    100mg
    115,00€
  • VU0155041

    CAS:
    VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
    Fórmula:C14H15Cl2NO3
    Pureza:99.52% - 99.56%
    Forma y color:Solid
    Peso molecular:316.18

    Ref: TM-T3565

    2mg
    38,00€
    5mg
    55,00€
    1mL*10mM (DMSO)
    60,00€
    10mg
    80,00€
    25mg
    138,00€
    50mg
    178,00€
    100mg
    285,00€
    200mg
    413,00€
  • VU0361737

    CAS:
    VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.
    Fórmula:C13H11ClN2O2
    Pureza:99.60% - 99.85%
    Forma y color:Solid
    Peso molecular:262.69

    Ref: TM-T6726

    1mL*10mM (DMSO)
    33,00€
    25mg
    44,00€
    50mg
    69,00€
    100mg
    100,00€
    500mg
    236,00€
  • ADX88178

    CAS:
    ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.
    Fórmula:C12H12N6S
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:272.33

    Ref: TM-T4500

    5mg
    35,00€
    1mL*10mM (DMSO)
    37,00€
    10mg
    55,00€
    25mg
    88,00€
    50mg
    142,00€
    100mg
    200,00€
  • JNJ-40411813

    CAS:

    JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).

    Fórmula:C20H25ClN2O
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:344.88

    Ref: TM-TQ0094

    1mg
    55,00€
    5mg
    117,00€
    10mg
    183,00€
    25mg
    306,00€
    50mg
    437,00€
    100mg
    562,00€
    200mg
    743,00€
  • CX614

    CAS:
    CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.
    Fórmula:C13H13NO4
    Pureza:97.37%
    Forma y color:Solid
    Peso molecular:247.25

    Ref: TM-T19698

    5mg
    52,00€
    1mL*10mM (DMSO)
    55,00€
    10mg
    78,00€
    25mg
    119,00€
    50mg
    172,00€
    100mg
    259,00€
    200mg
    388,00€