
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 255 productos de "GluR"
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Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Fórmula:C18H13ClFN3Pureza:98.35%Forma y color:SolidPeso molecular:325.77Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Fórmula:C21H11F6N5Pureza:99.77%Forma y color:SolidPeso molecular:447.34VU0650786
CAS:<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Fórmula:C18H15ClFN5O2Pureza:99.09%Forma y color:SolidPeso molecular:387.8DHPG
CAS:<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Fórmula:C8H9NO4Pureza:99.55%Forma y color:SolidPeso molecular:183.16Org-26576
CAS:<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Fórmula:C11H12N2O2Pureza:99.67%Forma y color:SolidPeso molecular:204.23LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Fórmula:C18H20ClNO4Pureza:97.96% - 99.68%Forma y color:SoildPeso molecular:349.81Piracetam
CAS:<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Fórmula:C6H10N2O2Pureza:97.16%Forma y color:Crystals From Isopropanol SolidPeso molecular:142.16γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Fórmula:C9H16N2O7Pureza:99.81%Forma y color:SolidPeso molecular:264.23(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Fórmula:C20H17F2N3O2Pureza:99.87%Forma y color:SolidPeso molecular:369.36(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Fórmula:C10H10ClNO6Pureza:98.80% - 99.89%Forma y color:SoildPeso molecular:275.64AZD-8529 mesylate
CAS:<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>Fórmula:C25H28F3N5O6SPureza:99.19%Forma y color:SolidPeso molecular:583.58KM02894
CAS:<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Fórmula:C7H9N3OS2Pureza:99.98%Forma y color:SolidPeso molecular:215.3NBQX disodium
CAS:<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Fórmula:C12H6N4Na2O6SPureza:97.6% - 98.22%Forma y color:SolidPeso molecular:380.2415LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Fórmula:C25H31F2NO11SForma y color:SolidPeso molecular:591.58LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SForma y color:SolidPeso molecular:628.03LY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Fórmula:C10H12N4O4SPureza:98%Forma y color:SolidPeso molecular:284.29ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Fórmula:C19H15FN2OPureza:99.98% - 99.98%Forma y color:SoildPeso molecular:306.33GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Forma y color:SolidPeso molecular:395.71mGluR5 modulator 1
CAS:<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Fórmula:C18H19ClFN3O2Forma y color:SolidPeso molecular:363.82JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Forma y color:Solid

