
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 255 productos de "GluR"
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CPPG
CAS:<p>CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.</p>Fórmula:C11H14NO5PForma y color:SolidPeso molecular:271.21FP0429
CAS:<p>FP0429 is an agonist of mGlu4.</p>Fórmula:C10H12N2O7Pureza:98%Forma y color:SolidPeso molecular:272.21LY 541850
CAS:<p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>Fórmula:C9H13NO4Pureza:98%Forma y color:SolidPeso molecular:199.2LY3020371 hydrochloride
CAS:<p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>Fórmula:C15H16ClF2NO5SForma y color:SolidPeso molecular:395.81PF470
CAS:<p>PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.</p>Fórmula:C18H16N6OForma y color:SolidPeso molecular:332.36Pomaglumetad methionil
CAS:<p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>Fórmula:C12H20N2O8S2Pureza:98%Forma y color:SolidPeso molecular:384.43YM 202074
CAS:<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Fórmula:C56H72N8O16S2Pureza:98%Forma y color:SolidPeso molecular:1177.34LY2979165
CAS:<p>LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.</p>Fórmula:C13H22N6O6SPureza:98.41%Forma y color:SolidPeso molecular:390.42Eglumegad
CAS:<p>Eglumegad is a highly effective and selective agonist of group II (mGlu2/3) receptor (IC50s: 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively).</p>Fórmula:C8H11NO4Forma y color:SolidPeso molecular:185.18YM-298198 hydrochloride
CAS:<p>mGlu1 receptor antagonist</p>Fórmula:C18H23ClN4OSPureza:98%Forma y color:SolidPeso molecular:378.919(RS)-APICA
CAS:<p>group II metabotropic glutamate receptor antagonist</p>Fórmula:C10H12NO5PForma y color:SolidPeso molecular:257.18Eglumegad hydrochloride
<p>Eglumegad (LY354740) hydrochloride is a potent, selective agonist for group II (mGlu2/3) receptors, showing IC50 values of 5 nM for mGlu2 and 24 nM for mGlu3 receptors in transfected human cells. This compound provides neuroprotection against NMDA-induced toxicity and exhibits anxiolytic- and antipsychotic-like properties [1].</p>Fórmula:C8H12ClNO4Forma y color:SolidPeso molecular:221.64VU0080241
CAS:<p>VU0080241 is a positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4).</p>Fórmula:C19H23N5Forma y color:SolidPeso molecular:321.42CMPDA
CAS:<p>CMPDA is a positive allosteric modulator of AMPA receptors [EC50s: 45.4 nM/63.4 nM for GluA2i/GluA2o receptor].</p>Fórmula:C16H28N2O4S2Pureza:98%Forma y color:SolidPeso molecular:376.53UBP1112
CAS:<p>group III mGlu receptor antagonist</p>Fórmula:C10H14NO5PPureza:98%Forma y color:SolidPeso molecular:259.2

