
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 265 productos de "GluR"
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VU 0285683
CAS:VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.Fórmula:C14H7FN4OPureza:99.98%Forma y color:SolidPeso molecular:266.23Ref: TM-T23509
2mg39,00€5mg60,00€1mL*10mM (DMSO)67,00€10mg74,00€25mg112,00€50mg161,00€100mg222,00€200mg301,00€MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFórmula:C21H22F3N5O2Forma y color:SolidPeso molecular:433.43MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Fórmula:C15H9FN2Pureza:99.80%Forma y color:SolidPeso molecular:236.24AMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.Fórmula:C15H6F6N4OSPureza:99.8%Forma y color:SolidPeso molecular:404.29Ref: TM-T37734
1mg116,00€5mg281,00€1mL*10mM (DMSO)310,00€10mg371,00€25mg595,00€50mg858,00€100mg1.189,00€JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Fórmula:C23H25F3N4Forma y color:SolidPeso molecular:414.47VU6005649
CAS:VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).Fórmula:C16H12F5N3OPureza:99.87%Forma y color:SolidPeso molecular:357.28mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41MGS-0039
CAS:MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.Fórmula:C15H14Cl2FNO5Pureza:98%Forma y color:SolidPeso molecular:378.18VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Fórmula:C10H11N3S2Forma y color:SolidPeso molecular:237.34Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Fórmula:C30H30O4Pureza:98%Forma y color:SolidPeso molecular:454.56Pomaglumetad methionil hydrochloride
CAS:LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.Fórmula:C12H19ClN2O7S2Pureza:98.57%Forma y color:SolidPeso molecular:402.87VU0360172
CAS:VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).Fórmula:C18H15FN2OPureza:99.56%Forma y color:SolidPeso molecular:294.32FPTQ
CAS:FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].Fórmula:C17H12FN5Pureza:99.68% - 99.88%Forma y color:SolidPeso molecular:305.31Ref: TM-T5509
500mgA consultar1mg52,00€2mg70,00€5mg105,00€1mL*10mM (DMSO)110,00€10mg152,00€25mg294,00€50mg398,00€100mg527,00€VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Fórmula:C21H19F3N4O4Pureza:99.61% - 99.74%Forma y color:SolidPeso molecular:448.4Ref: TM-T13323
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg119,00€25mg225,00€50mg404,00€100mg592,00€L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Fórmula:C4H10NO5PPureza:98%Forma y color:White To Off-White Crystalline PowderPeso molecular:183.1Licostinel
CAS:Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.Fórmula:C8H3Cl2N3O4Pureza:98.02%Forma y color:SolidPeso molecular:276.03cis-PDA
CAS:cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.Fórmula:C7H11NO4Pureza:98.71%Forma y color:White SolidPeso molecular:173.17MTPG
CAS:Group II/group III metabotropic glutamate receptor antagonistFórmula:C10H11N5O2Pureza:98%Forma y color:SolidPeso molecular:233.23(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Fórmula:C6H10N2O4Pureza:98%Forma y color:SolidPeso molecular:174.15Philanthotoxin 74 dihydrochloride
CAS:Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.Fórmula:C24H44Cl2N4O3Pureza:99.75%Forma y color:SolidPeso molecular:507.54
