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GluR

GluR

Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.

Se han encontrado 265 productos de "GluR"

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  • VU 0285683

    CAS:
    VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
    Fórmula:C14H7FN4O
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:266.23

    Ref: TM-T23509

    2mg
    39,00€
    5mg
    60,00€
    1mL*10mM (DMSO)
    67,00€
    10mg
    74,00€
    25mg
    112,00€
    50mg
    161,00€
    100mg
    222,00€
    200mg
    301,00€
  • MK-8768

    CAS:
    MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by
    Fórmula:C21H22F3N5O2
    Forma y color:Solid
    Peso molecular:433.43

    Ref: TM-T79302

    5mg
    A consultar
    50mg
    A consultar
  • MFZ 10-7

    CAS:
    MFZ 10-7 is anegative allosteric modulator of the mGluR5.
    Fórmula:C15H9FN2
    Pureza:99.80%
    Forma y color:Solid
    Peso molecular:236.24

    Ref: TM-T22976

    1mg
    38,00€
    2mg
    52,00€
    5mg
    75,00€
    10mg
    110,00€
    25mg
    245,00€
    50mg
    354,00€
    100mg
    515,00€
    200mg
    700,00€
  • AMPA receptor modulator-2

    CAS:
    AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
    Fórmula:C15H6F6N4OS
    Pureza:99.8%
    Forma y color:Solid
    Peso molecular:404.29

    Ref: TM-T37734

    1mg
    116,00€
    5mg
    281,00€
    1mL*10mM (DMSO)
    310,00€
    10mg
    371,00€
    25mg
    595,00€
    50mg
    858,00€
    100mg
    1.189,00€
  • JNJ-46281222

    CAS:
    JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.
    Fórmula:C23H25F3N4
    Forma y color:Solid
    Peso molecular:414.47

    Ref: TM-T15618

    25mg
    1.288,00€
    50mg
    1.674,00€
    100mg
    2.872,00€
  • VU6005649

    CAS:
    VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).
    Fórmula:C16H12F5N3O
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:357.28

    Ref: TM-T13321

    1mL*10mM (DMSO)
    34,00€
    10mg
    42,00€
    25mg
    78,00€
    50mg
    112,00€
    100mg
    172,00€
    200mg
    245,00€
  • mGluR5 antagonist-1

    CAS:
    mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].
    Fórmula:C23H18N4O2
    Forma y color:Solid
    Peso molecular:382.41

    Ref: TM-T81801

    5mg
    A consultar
    50mg
    A consultar
  • MGS-0039

    CAS:
    MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.
    Fórmula:C15H14Cl2FNO5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:378.18

    Ref: TM-T28034

    25mg
    1.773,00€
    50mg
    2.322,00€
    100mg
    3.060,00€
  • VU0029251

    CAS:
    VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.
    Fórmula:C10H11N3S2
    Forma y color:Solid
    Peso molecular:237.34

    Ref: TM-T78600

    1mg
    87,00€
    5mg
    379,00€
    10mg
    648,00€
    25mg
    1.243,00€
  • Biphenylindanone A

    CAS:
    Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.
    Fórmula:C30H30O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:454.56

    Ref: TM-T14615

    5mg
    239,00€
    10mg
    414,00€
    25mg
    954,00€
  • Pomaglumetad methionil hydrochloride

    CAS:
    LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.
    Fórmula:C12H19ClN2O7S2
    Pureza:98.57%
    Forma y color:Solid
    Peso molecular:402.87

    Ref: TM-T61972

    1mg
    190,00€
    5mg
    485,00€
    10mg
    700,00€
    25mg
    1.063,00€
    50mg
    1.459,00€
  • VU0360172

    CAS:
    VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).
    Fórmula:C18H15FN2O
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:294.32

    Ref: TM-T29126

    1mg
    34,00€
    1mL*10mM (DMSO)
    73,00€
    5mg
    77,00€
    10mg
    110,00€
    25mg
    215,00€
    50mg
    334,00€
    100mg
    474,00€
  • FPTQ

    CAS:
    FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].
    Fórmula:C17H12FN5
    Pureza:99.68% - 99.88%
    Forma y color:Solid
    Peso molecular:305.31

    Ref: TM-T5509

    500mg
    A consultar
    1mg
    52,00€
    2mg
    70,00€
    5mg
    105,00€
    1mL*10mM (DMSO)
    110,00€
    10mg
    152,00€
    25mg
    294,00€
    50mg
    398,00€
    100mg
    527,00€
  • VU6012962

    CAS:
    VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).
    Fórmula:C21H19F3N4O4
    Pureza:99.61% - 99.74%
    Forma y color:Solid
    Peso molecular:448.4

    Ref: TM-T13323

    1mg
    34,00€
    2mg
    49,00€
    5mg
    74,00€
    1mL*10mM (DMSO)
    82,00€
    10mg
    119,00€
    25mg
    225,00€
    50mg
    404,00€
    100mg
    592,00€
  • L-AP4

    CAS:
    L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).
    Fórmula:C4H10NO5P
    Pureza:98%
    Forma y color:White To Off-White Crystalline Powder
    Peso molecular:183.1

    Ref: TM-T15692

    1mg
    178,00€
    5mg
    316,00€
    10mg
    530,00€
    50mg
    2.242,00€
  • Licostinel

    CAS:
    Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia.
    Fórmula:C8H3Cl2N3O4
    Pureza:98.02%
    Forma y color:Solid
    Peso molecular:276.03

    Ref: TM-T27828

    5mg
    57,00€
    1mL*10mM (DMSO)
    60,00€
    10mg
    90,00€
    25mg
    170,00€
    50mg
    268,00€
    100mg
    399,00€
  • cis-PDA

    CAS:
    cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.
    Fórmula:C7H11NO4
    Pureza:98.71%
    Forma y color:White Solid
    Peso molecular:173.17

    Ref: TM-T20571

    50mg
    A consultar
    10mg
    33,00€
    25mg
    50,00€
  • MTPG

    CAS:
    Group II/group III metabotropic glutamate receptor antagonist
    Fórmula:C10H11N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:233.23

    Ref: TM-T23033

    25mg
    1.908,00€
    50mg
    2.502,00€
    100mg
    3.330,00€
  • (2R,4R)-APDC

    CAS:
    (2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.
    Fórmula:C6H10N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:174.15

    Ref: TM-T10095

    10mg
    1.035,00€
    50mg
    4.311,00€
  • Philanthotoxin 74 dihydrochloride

    CAS:
    Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.
    Fórmula:C24H44Cl2N4O3
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:507.54

    Ref: TM-T16524

    50mg
    A consultar
    1mg
    49,00€
    5mg
    139,00€
    1mL*10mM (DMSO)
    180,00€