BACE
Los inhibidores de BACE son compuestos que tienen como objetivo la enzima Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), que es crucial para la producción de beta-amiloide, una proteína asociada con la formación de placas amiloides en la enfermedad de Alzheimer. Al inhibir BACE, estos compuestos buscan reducir la producción de beta-amiloide y su acumulación en el cerebro, lo que podría ralentizar la progresión de la enfermedad de Alzheimer. Los inhibidores de BACE son un enfoque principal en el desarrollo de estrategias terapéuticas para las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos inhibidores de BACE para apoyar su investigación en la enfermedad de Alzheimer, la biología amiloide y la neurodegeneración.
Se han encontrado 35 productos para "BACE".
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Elenbecestat
CAS:Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.Fórmula:C19H18F3N5O2SPureza:99.95%Forma y color:White SolidPeso molecular:437.439BACE1-IN-4
CAS:BACE1-IN-4 is a selective BACE1 inhibitor with nanomolar activity and significantly weaker BACE2 inhibition, and can be used for research on amyloid precursor protein secretase biology and Alzheimer's disease-related drug discovery.Fórmula:C21H23F2N5O4S2Pureza:99.66%Forma y color:SolidPeso molecular:511.57Anti-BACE1 Antibody-FITC (8D358)
Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.Forma y color:Odour LiquidAnti-BACE1 Antibody-PE (8D358)
Anti-BACE1 Antibody-PE (8D358) is a PE-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-PE (8D358) can be used in FCM.Forma y color:Odour LiquidAnti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.Forma y color:Odour LiquidAnti-BACE1 Antibody (3R945)
Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.Forma y color:Odour LiquidAnti-BACE1 Antibody (8D358)
Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.Forma y color:Odour LiquidBACE1 Protein, Human, Recombinant (His)
BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLCForma y color:Lyophilized PowderPeso molecular:49.5 kDa (predicted); 55-70 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:75.2 kDa (predicted, pro-form); 72.6 kDa (predicted, mature-form); 85-100 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.Forma y color:Lyophilized PowderPeso molecular:49 kDa (predicted); 65 kDa (reducing condition, due to glycosylation)Tenuifolin
CAS:Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.Fórmula:C36H56O12Pureza:98.71% - 99.90%Forma y color:Yellow SolidPeso molecular:680.8226LY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Fórmula:C18H16F2N4O2SPureza:99% - 99.75%Forma y color:SolidPeso molecular:390.407Aloenin
CAS:1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.Fórmula:C19H22O10Pureza:99.42% - 99.69%Forma y color:SolidPeso molecular:410.372Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Fórmula:C19H21NO4Pureza:98.62% - 99.64%Forma y color:White SolidPeso molecular:327.3743Eslicarbazepine Acetate
CAS:Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.Fórmula:C17H16N2O3Pureza:99.58% - >99.99%Forma y color:White SolidPeso molecular:296.32Aloeresin D
CAS:Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).Fórmula:C29H32O11Pureza:98.11% - 99.57%Forma y color:SolidPeso molecular:556.5578Verubecestat
CAS:Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.Fórmula:C17H17F2N5O3SPureza:94.64% - 99.55%Forma y color:SolidPeso molecular:409.41LY2811376
CAS:LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).Fórmula:C15H14F2N4SPureza:97.92% - 99%Forma y color:SolidPeso molecular:320.36BACE-IN-1 acetate
BACE-IN-1 acetate (350228-37-4), a BACE1 inhibitor with three disulfide bonds and N-linked glycosylation, is used in assays.Fórmula:C75H122N16O29Pureza:99.71%Forma y color:SolidPeso molecular:1711.86
