Proteasoma

Saxagliptin is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).

Linagliptin is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic …

Sitagliptin, a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This …

ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.

Vildagliptin is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. …

PTP1B-IN-9 is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.

Pepstatin is a specific aspartic proteases inhibitor produced by actinomycetes, and inhibits the aspartic proteases …

RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.

Racecadotril has been investigated for the basic science and treatment of Diarrhea, Acute Diarrhea, and …

Arimoclomol maleate (BRX-220) is a heat shock protein (HSP) co-inducer.

Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated …

Retagliptin Phosphate is pharmaceutical composition of DPP-4 inhibitor, for treating type-2 diabetes.

Trelagliptin is a highly specific and long-acting DPP-4 inhibitor.

Aprotinin a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases …

DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no …

UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s …

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the …

Lactacystin is an antibiotic Streptomyces spp. the metabolite and is an effective and selective proteasome …

Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies …

Sitagliptin phosphate is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 …

KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 …

3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in …

Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain …

Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing …

1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 …

LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an …

PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor. PR 39 (porcine) …

Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)

MG-115 is a potent and reversible inhibitor of proteasome , with K i s of …

PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM). PR-924 …

Oprozomib (ONX 0912) , an inhibitor for CT-L activity of 20S proteasome β5(IC50=36 nM)/LMP7(IC50=82 nM), …

UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 …

CEP-18770 is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). …

MUN57694 is an inhibitor of 26S proteasome.

Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.

Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.

Trelagliptin(SYR-472) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of …

An antiproliferatve agent of breast adenocarcinoma cells.

MG-101 (ALLN) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal …

Bortezomib-pinanediol is a proteasome inhibitor. is a prodrug of Bortezomib.

DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride is an inhibitor of trypsin-like protease. N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride exhibits …

Celastrol is an effective proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome(IC50=2.5 …

Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is …

AOB2796 is a novel PAR2 agonist; activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis …

AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). …

Alogliptin(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater …

AZD7986 is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 …

1. Isoginkgetin, a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion …

PSI is a proteasome inhibitor.

Enoxolone (INN, BAN; also known as glycyrrhetinic acid) is a pentacyclic triterpenoid derivative of the …

TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S …

Ixazomib citrate is a prodrug of Ixazomib (MMLN-2238). MLN9708 is an orally bioavailable second generation …

MG-132 is a potent cell-permeable 26S proteasome inhibitor (IC50: 100 nM). It also inhibits calpain …

NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory …

ARV-471 is a orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 …

Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and …

Calpeptin is a potent, cell-permeable calpain inhibitor.

Talabostat mesylate is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 …