PAI-1
El Plasminogen Activator Inhibitor-1 (PAI-1) es un inhibidor de la serina proteasa que regula la fibrinólisis al inhibir el activador del plasminógeno tisular (tPA) y la uroquinasa (uPA). Niveles elevados de PAI-1 están asociados con un mayor riesgo de trombosis, enfermedades cardiovasculares y síndrome metabólico. Los inhibidores de PAI-1 están siendo investigados por su potencial en el tratamiento de estas condiciones. En CymitQuimica, ofrecemos inhibidores de PAI-1 para apoyar su investigación en hematología, salud cardiovascular y enfermedades metabólicas.
Se han encontrado 32 productos para "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Forma y color:White SolidPeso molecular:629.81PAI-1-IN-1
CAS:PAI-1-IN-1 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor that affects fibrinolytic activity by modulating PAI-1-mediated inhibition of tPA/uPA.Fórmula:C23H14ClN2NaO3Pureza:99.42%Peso molecular:424.81D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.PAI-1-IN-2
CAS:5-Chloro-2-[[[2-[[3-(furan-2-yl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid is an oral PAI-1 inhibitor improving metabolism and hepatic steatosis.Fórmula:C21H17ClN2O6Pureza:98.78%Peso molecular:428.82Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Forma y color:Yellow SolidAngstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFórmula:C39H62N10O15Pureza:99.97%Forma y color:SolidPeso molecular:910.9676Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Forma y color:SolidPeso molecular:1904.11UK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Fórmula:C72H105N19O25S3Forma y color:SolidPeso molecular:1732.91Stromab
Stromab (DS9231; TS-23; CSL-301) is a human-derived IgG1 monoclonal antibody (mAb) that targets SerpinF2. It can be utilized for research in ischemic stroke, pulmonary embolism, myocardial infarction, and thrombosis. The suggested isotype control is Human IgG1 lambda, Isotype Control.6-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Fórmula:C6H13NO2Forma y color:SolidPeso molecular:131.1729CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Fórmula:C25H20F3NO12Pureza:99.08%Forma y color:Yellow SolidPeso molecular:583.42Anti-Human SERPINE1 Antibody
Anti-SERPINE1 Antibody targets PAI-1, promoting fibrinolysis and reducing fibrosis by neutralizing its activity, and blocks PAI-1-mediated tumor immune evasion.Pureza:95% - 97.6% (SDS-PAGE); 99.1% (SEC-HPLC)Peso molecular:146.07 kDa (Predicted)Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Forma y color:White SolidPeso molecular:316.3484Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:439.38TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Fórmula:C24H20N2O6S4Pureza:96.91%Forma y color:SolidPeso molecular:560.69TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Fórmula:C28H27ClN3NaO5Pureza:98.8% - 99.74%Forma y color:SolidPeso molecular:543.98Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Fórmula:C16H20O6Pureza:99.8% - 99.85%Forma y color:SolidPeso molecular:308.3264UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Fórmula:C14H16ClN5O4SPureza:95.81% - 99.77%Forma y color:SolidPeso molecular:385.826TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Fórmula:C21H17ClN2O6Pureza:0.998% - 99.23%Forma y color:White SolidPeso molecular:428.822MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Fórmula:C10H10F3N3O3Forma y color:SolidPeso molecular:277.20
