PAI-1
El Plasminogen Activator Inhibitor-1 (PAI-1) es un inhibidor de la serina proteasa que regula la fibrinólisis al inhibir el activador del plasminógeno tisular (tPA) y la uroquinasa (uPA). Niveles elevados de PAI-1 están asociados con un mayor riesgo de trombosis, enfermedades cardiovasculares y síndrome metabólico. Los inhibidores de PAI-1 están siendo investigados por su potencial en el tratamiento de estas condiciones. En CymitQuimica, ofrecemos inhibidores de PAI-1 para apoyar su investigación en hematología, salud cardiovascular y enfermedades metabólicas.
Se han encontrado 32 productos para "PAI-1".
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SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Fórmula:C29H29NNa2O6Pureza:98.29%Forma y color:SolidPeso molecular:533.52UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Fórmula:C14H17Cl2N5O4SPureza:98%Forma y color:SolidPeso molecular:422.287Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Fórmula:C32H31N5OPureza:99.75%Forma y color:Yellow SolidPeso molecular:501.6214p-Aminobenzamidine dihydrochloride
CAS:4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase typeFórmula:C7H11Cl2N3Pureza:99.00% - 99.77%Forma y color:SolidPeso molecular:208.088CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Forma y color:Odour LiquidAleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFórmula:C28H27NO3Pureza:99.21%Forma y color:SolidPeso molecular:425.5189AZ3976
CAS:AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.Fórmula:C15H19N5O3Pureza:98.14%Forma y color:White SolidPeso molecular:317.3431ZK824190
CAS:ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.Fórmula:C22H20F2N2O4Pureza:98.84%Forma y color:White SolidPeso molecular:414.402PPACK
CAS:PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.Fórmula:C21H31ClN6O3Pureza:98%Forma y color:SolidPeso molecular:450.96BT-114143
CAS:BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.Fórmula:C8H11N2O3PForma y color:SolidPeso molecular:214.158GGACK
CAS:GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Fórmula:C14H25ClN6O5Forma y color:SolidPeso molecular:392.84GGACK hydrochloride
GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Fórmula:C14H26Cl2N6O5Forma y color:SolidPeso molecular:428.13417
