PAI-1
El Plasminogen Activator Inhibitor-1 (PAI-1) es un inhibidor de la serina proteasa que regula la fibrinólisis al inhibir el activador del plasminógeno tisular (tPA) y la uroquinasa (uPA). Niveles elevados de PAI-1 están asociados con un mayor riesgo de trombosis, enfermedades cardiovasculares y síndrome metabólico. Los inhibidores de PAI-1 están siendo investigados por su potencial en el tratamiento de estas condiciones. En CymitQuimica, ofrecemos inhibidores de PAI-1 para apoyar su investigación en hematología, salud cardiovascular y enfermedades metabólicas.
Se han encontrado 29 productos para "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Forma y color:White SolidPeso molecular:629.81Ref: TM-T13257
1mg60,00€2mg89,00€5mg138,00€1mL*10mM (DMSO)155,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€D-Val-Leu-Lys-AMC TFA
D-Val-Leu-Lys-AMC TFA is a selective fluorescent peptide substrate for plasmin. It is employed for the quantitative assessment of plasmin enzymatic activity. The excitation wavelength is 360-380 nm, and the emission wavelength is 440-460 nm.CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Forma y color:Odour LiquidGGACK hydrochloride
GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Fórmula:C14H26Cl2N6O5Forma y color:SolidPeso molecular:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Forma y color:Yellow SolidUK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Fórmula:C72H105N19O25S3Forma y color:SolidPeso molecular:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Forma y color:SolidPeso molecular:1904.11Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFórmula:C39H62N10O15Pureza:99.97%Forma y color:SolidPeso molecular:910.97D-Val-Leu-Arg-pNA hydrochloride
CAS:D-Val-Leu-Arg-pNA hydrochloride is a substrate for glandular kallikrein. It can be utilized to measure the activity of plasminogen activators and plasmin. This compound is also employed in studying fibrinolytic activity in various organisms, such as bacteria and worms.Fórmula:C23H39ClN8O5Peso molecular:543.076-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Fórmula:C6H13NO2Forma y color:SolidPeso molecular:131.17CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Fórmula:C25H20F3NO12Pureza:99.08%Forma y color:Yellow SolidPeso molecular:583.42Ref: TM-T25217
1mg57,00€5mg123,00€1mL*10mM (DMSO)158,00€10mg200,00€25mg423,00€50mg677,00€100mg1.063,00€TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Forma y color:White SolidPeso molecular:428.82UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Fórmula:C14H16ClN5O4SPureza:95.81% - 99.77%Forma y color:SolidPeso molecular:385.83Ref: TM-T3442
1mg49,00€2mg63,00€5mg103,00€1mL*10mM (DMSO)111,00€10mg170,00€25mg306,00€50mg460,00€100mg668,00€500mg1.395,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Forma y color:White SolidPeso molecular:316.35TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Fórmula:C24H20N2O6S4Pureza:96.91%Forma y color:SolidPeso molecular:560.69TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Fórmula:C28H27ClN3NaO5Pureza:98.8% - 99.74%Forma y color:SolidPeso molecular:543.98Ref: TM-T4255
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg160,00€50mg231,00€100mg334,00€200mg465,00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Fórmula:C16H20O6Pureza:99.8% - 99.85%Forma y color:SolidPeso molecular:308.33Ref: TM-T4S0592
2mg37,00€5mg52,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg320,00€Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Fórmula:C10H10F3N3O3Forma y color:SolidPeso molecular:277.20UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Fórmula:C14H17Cl2N5O4SPureza:98%Forma y color:SolidPeso molecular:422.29
