Acetil-CoA Carboxilasa
Los inhibidores de Acetil-CoA Carboxilasa (ACC) son compuestos que inhiben la actividad de ACC, una enzima clave en la biosíntesis de ácidos grasos al convertir acetil-CoA en malonil-CoA. Inhibir ACC puede reducir la síntesis de lípidos, lo que hace que estos inhibidores sean valiosos en la investigación relacionada con trastornos metabólicos, obesidad y cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de ACC para apoyar su investigación en vías metabólicas, metabolismo de lípidos y desarrollo terapéutico.
Se han encontrado 50 productos para "Acetil-CoA Carboxilasa".
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S-2E
CAS:S-2E, an oral inhibitor of HMG-CoA reductase/acetyl-CoA carboxylase, treats hyperlipidemia.Fórmula:C22H25NO4Forma y color:SolidPeso molecular:367.44AD-5584
CAS:AD-5584, an ACSS2 inhibitor with blood-brain permeability, significantly reduces lipid storage and colony formation while increasing cell death, demonstrating antitumor activity [1].Fórmula:C22H24ClFN4OForma y color:SolidPeso molecular:414.9Quizalofop
CAS:Quizalofop (Xylafop) is a reagent of biochemical.Fórmula:C17H13ClN2O4Pureza:97.14%Forma y color:White SolidPeso molecular:344.75Ref: TM-T19959
5mg52,00€1mL*10mM (DMSO)65,00€10mg73,00€25mg105,00€50mg156,00€100mg224,00€500mg557,00€THR-β agonist 9
CAS:THR-β agonist 9 is a potent and selective THR-β activator, which shows sensitivity to His435 mutations with an EC50 of 3.2 nM. It demonstrates moderate selectivity, approximately 10-fold, and effectively activates various His435 mutants (H435A, H435Y, and H435R), with EC50 values ranging from 134.2 nM to 515.5 nM. THR-β agonist 9 presents potential for research into conditions such as dyslipidemia, metabolic syndrome-associated steatohepatitis (MASH), and resistance to thyroid hormone (RTH).Fórmula:C23H18N2O6Peso molecular:418.40AMPK activator 16
CAS:AMPK activator16 (compound 6) functions as an AMP-activated protein kinase (AMPK) inhibitor. It interacts effectively with crucial AMPK residues, significantly activating the enzyme. In N2a cells, AMPK activator16 enhances the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) and phosphorylated raptor (p-raptor).Fórmula:C23H20ClNO5SForma y color:SolidPeso molecular:457.927LCB-2122
CAS:LCB-2122 is an adenosine-like nucleoside analog featuring a C2'-stereoisomeric all-carbon quaternary carbon center. It inhibits doxorubicin-induced myocardial apoptosis with an IC50 value of 0.5 μM and also suppresses imatinib-induced apoptosis. LCB-2122 activates the AMPK signaling pathway, inducing the phosphorylation of AMPK and its downstream substrate acetyl-CoA carboxylase (ACC). Additionally, LCB-2122 alleviates mitochondrial damage caused by doxorubicin and is used in heart failure research.Fórmula:C16H25ClN5O7PPeso molecular:465.83CKBA
CAS:CKBA, a derivative of AKBA, acts as an acetyl-CoA carboxylase 1 (ACC1) inhibitor with an IC50 of 5.02 μM. It inhibits Th17 cell differentiation, displaying IC50 values of 3.28 μM in mouse cells and 3.61 μM in human cells. CKBA ointment significantly alleviates psoriasis-like inflammation in mice and can be used for psoriasis research.Fórmula:C37H56O5Peso molecular:580.85ACC-IN-1
CAS:ACC-IN-1 (Compound B1) is an allosteric inhibitor of acetyl-CoA carboxylase (ACC). It targets ACC to regulate lipid metabolism, potentially improving liver steatosis and inflammation associated with non-alcoholic steatohepatitis (NASH).Fórmula:C30H33N3O8SPeso molecular:595.66QPP-I-6
CAS:QPP-I-6, an inhibitor of acetyl-coenzyme A carboxylase (ACCase), exhibits herbicidal activity by inducing cell membrane permeability [1].Fórmula:C21H19FN2O5Peso molecular:398.38Moiramide B
CAS:Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.Fórmula:C25H31N3O5Pureza:98.53% - 99.74%Forma y color:SolidPeso molecular:453.53
