Cisteína proteasa
Los inhibidores de proteasas de cisteína son compuestos que se dirigen e inhiben a las proteasas de cisteína, una clase de enzimas que descomponen proteínas al romper enlaces peptídicos en los que un residuo de cisteína actúa como nucleófilo. Estas enzimas están involucradas en varios procesos fisiológicos, como la apoptosis, la respuesta inmune y el recambio de proteínas. Los inhibidores de proteasas de cisteína son fundamentales para estudiar enfermedades como el cáncer, los trastornos neurodegenerativos y las infecciones parasitarias. En CymitQuimica, ofrecemos inhibidores de proteasas de cisteína para apoyar su investigación en proteólisis, regulación celular y descubrimiento de fármacos.
Se han encontrado 111 productos de "Cisteína proteasa"
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Mpro/Cathepsin L-IN-1
Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.Fórmula:C24H32FN3O4Peso molecular:445.23768Ac-PLVE-FMK
CAS:Ac-PLVE-FMK (Ac-Pro-Leu-Val-Glu(OMe)-CH2F), a tetrapeptidyl fluoromethylketone (FMKs), serves as a cathepsin inhibitor. It is utilized in cancer research [1].Fórmula:C25H41FN4O7Pureza:98%Forma y color:SolidPeso molecular:528.61Z-Phe-Tyr(tBu)-diazomethylketone
CAS:Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.Fórmula:C31H34N4O5Forma y color:SolidPeso molecular:542.636Z-L(D-Val)G-CHN2
Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.Fórmula:C22H31N5O5Pureza:98%Forma y color:SolidPeso molecular:445.51Relacatib
CAS:Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Fórmula:C27H32N4O6SForma y color:SolidPeso molecular:540.64Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFórmula:C24H35N5O4·xC2HF3O2Forma y color:SolidLeupeptin
CAS:Leupeptin, from actinomycetes, inhibits various proteases (e.g., trypsin, plasmin, kallikrein, papain, cathepsin B) but not α-chymotrypsin/thrombin.Fórmula:C20H38N6O4Pureza:98%Forma y color:SolidPeso molecular:426.562Z-FG-NHO-Bz
CAS:Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].Fórmula:C26H25N3O6Forma y color:SolidPeso molecular:475.49Cathepsin D and E FRET Substrate acetate
Fluorogenic substrate for cathepsins D & E, not B/H/L; useful in their mechanistic studies.Fórmula:C86H124N22O21Pureza:95.63%Forma y color:SolidPeso molecular:1802.04N-CBZ-Phe-Arg-AMC TFA
N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.Fórmula:C35H37F3N6O8Pureza:99.88%Forma y color:SolidPeso molecular:726.7LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Fórmula:C13H15ClN2O2Forma y color:SolidPeso molecular:266.72L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Forma y color:SolidPeso molecular:466.6Ref: TM-T21616
2mg39,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg177,00€50mg299,00€100mg432,00€200mg602,00€Aloxistatin
CAS:Aloxistatin (E64d) inhibits cysteine proteases, blocks calpain in platelets, and prevents blood clotting.Fórmula:C17H30N2O5Pureza:99.46% - 99.69%Forma y color:SolidPeso molecular:342.43Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Forma y color:White To Off-White Solid PowderPeso molecular:411.54Ref: TM-T1850
2mg39,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg94,00€25mg212,00€50mg358,00€100mg572,00€200mg803,00€MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Fórmula:C22H26N2O4Pureza:95.06%Forma y color:SolidPeso molecular:382.45Ref: TM-T2470
1mg34,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)75,00€10mg90,00€25mg128,00€50mg167,00€100mg284,00€KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Fórmula:C14H12BrN3OSPureza:99.6%Forma y color:SolidPeso molecular:350.23Ref: TM-T27730
1mg65,00€5mg138,00€1mL*10mM (DMSO)152,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€200mg928,00€2-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Fórmula:C5H3N3Pureza:99.27%Forma y color:Crystalline SolidPeso molecular:105.1LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Forma y color:SolidPeso molecular:484.52Ref: TM-TQ0116
1mg90,00€2mg130,00€5mg198,00€1mL*10mM (DMSO)207,00€10mg263,00€25mg462,00€50mg672,00€100mg945,00€CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Forma y color:SolidPeso molecular:397.47E 64c
CAS:E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.Fórmula:C15H26N2O5Pureza:98.73%Forma y color:SolidPeso molecular:314.38
