Cisteína proteasa
Los inhibidores de proteasas de cisteína son compuestos que se dirigen e inhiben a las proteasas de cisteína, una clase de enzimas que descomponen proteínas al romper enlaces peptídicos en los que un residuo de cisteína actúa como nucleófilo. Estas enzimas están involucradas en varios procesos fisiológicos, como la apoptosis, la respuesta inmune y el recambio de proteínas. Los inhibidores de proteasas de cisteína son fundamentales para estudiar enfermedades como el cáncer, los trastornos neurodegenerativos y las infecciones parasitarias. En CymitQuimica, ofrecemos inhibidores de proteasas de cisteína para apoyar su investigación en proteólisis, regulación celular y descubrimiento de fármacos.
Se han encontrado 139 productos para "Cisteína proteasa".
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Cathepsin Inhibitor 4
Cathepsin Inhibitor 4 (Compound 45) is a selective inhibitor of Cathepsin S, with a Ki value of 0.04 nM.
Fórmula:C24H35N3O5Peso molecular:445.25767CTSL/CAPN1-IN-1
CTSL/CAPN1-IN-1 (compound 14a) is an orally active inhibitor targeting CTSL and CAPN1, with IC50 values of 3.34 nM and 375.1 nM, respectively. It exhibits both anti-coronavirus and anti-inflammatory activities.Fórmula:C34H33FN4O6Forma y color:SolidPeso molecular:612.238416,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFórmula:C30H42N2O4SForma y color:SolidPeso molecular:526.73Cathepsin K inhibitor 7
Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.Forma y color:Odour SolidProtease Inhibitor Library
A unique collection of xnum protease and proteasome inhibitors for research in chemical genomics, and drug screening;Forma y color:Odour SolidRef: TM-L1100
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarCathepsin L-IN-5
CathepsinL-IN-5 (D6-3) is a potent inhibitor of Cathepsin L (CatL) with an IC50 value of 0.27 nM. It effectively blocks the function of CatL and significantly impedes the entry of SARS-CoV-2 pseudovirus into cells by inhibiting the cleavage of the spike protein. CathepsinL-IN-5 is applicable for research on infections.Forma y color:Odour SolidSmCB1-IN-1
SmCB1-IN-1 (Compound 2h) is an inhibitor of the Schistosoma mansoni cathepsin B1 (SmCB1) with a Ki of 0.05 μM. It demonstrates selectivity towards non-target human proteases, showing inhibition rates of 29% for CatB and 37% for CatL at 20 μM. At 1 μM, SmCB1-IN-1 inhibits 68% of Schistosoma mansoni.Fórmula:C26H25NO6SForma y color:SolidPeso molecular:479.14026Z-Arg-Arg-βNA acetate
CAS:Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.Fórmula:C32H43N9O6Forma y color:SolidPeso molecular:649.74Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Forma y color:SolidPeso molecular:411.54CA-074 methyl ester
CAS:CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Forma y color:SolidPeso molecular:397.47Odanacatib
CAS:Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.Fórmula:C25H27F4N3O3SPureza:98.53% - 99.53%Forma y color:SolidPeso molecular:525.56LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Forma y color:White SolidPeso molecular:484.52Ref: TM-TQ0116
1mg90,00€5mg198,00€1mL*10mM (DMSO)207,00€10mg263,00€25mg385,00€50mg557,00€100mg782,00€2-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Fórmula:C5H3N3Pureza:99.27%Forma y color:SolidPeso molecular:105.1KGP94
CAS:KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.Fórmula:C14H12BrN3OSPureza:99.6%Forma y color:White SolidPeso molecular:350.23Ref: TM-T27730
1mg65,00€5mg138,00€1mL*10mM (DMSO)152,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€200mg928,00€Aloxistatin
CAS:Aloxistatin (E64d) inhibits cysteine proteases, blocks calpain in platelets, and prevents blood clotting.Fórmula:C17H30N2O5Pureza:99.46% - 99.69%Forma y color:SolidPeso molecular:342.43L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Forma y color:SolidPeso molecular:466.6Ref: TM-T21616
2mg39,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg177,00€50mg299,00€100mg432,00€200mg602,00€MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Fórmula:C22H26N2O4Pureza:95.06%Forma y color:SolidPeso molecular:382.45Ref: TM-T2470
1mg34,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)75,00€10mg90,00€25mg128,00€50mg167,00€100mg284,00€E 64c
CAS:E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.Fórmula:C15H26N2O5Pureza:98.73%Forma y color:SolidPeso molecular:314.38JTE-607
CAS:JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.Fórmula:C25H33Cl4N3O5Pureza:97.88%Forma y color:White SolidPeso molecular:597.36Ref: TM-T27695
1mg42,00€5mg93,00€1mL*10mM (DMSO)109,00€10mg150,00€25mg310,00€50mg492,00€100mg707,00€200mg973,00€(1S,2R)-Alicapistat
CAS:(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.Fórmula:C25H27N3O4Pureza:99.60%Forma y color:White SolidPeso molecular:433.5Ref: TM-T60150
1mg64,00€5mg142,00€1mL*10mM (DMSO)167,00€10mg197,00€25mg299,00€50mg400,00€100mg537,00€
