Cisteína proteasa
Los inhibidores de proteasas de cisteína son compuestos que se dirigen e inhiben a las proteasas de cisteína, una clase de enzimas que descomponen proteínas al romper enlaces peptídicos en los que un residuo de cisteína actúa como nucleófilo. Estas enzimas están involucradas en varios procesos fisiológicos, como la apoptosis, la respuesta inmune y el recambio de proteínas. Los inhibidores de proteasas de cisteína son fundamentales para estudiar enfermedades como el cáncer, los trastornos neurodegenerativos y las infecciones parasitarias. En CymitQuimica, ofrecemos inhibidores de proteasas de cisteína para apoyar su investigación en proteólisis, regulación celular y descubrimiento de fármacos.
Se han encontrado 139 productos para "Cisteína proteasa".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Fórmula:C19H35N3O4SPureza:98%Forma y color:SolidPeso molecular:401.56S 2160
CAS:S 2160 is a synthetic chromogenic substrate for thrombin.Fórmula:C33H40N8O6Forma y color:SolidPeso molecular:644.72Cathepsin Inhibitor 1
CAS:Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.Fórmula:C20H24ClN5O2Pureza:99.78%Forma y color:SolidPeso molecular:401.89Ref: TM-T6015
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg144,00€25mg236,00€50mg371,00€100mg522,00€200mg743,00€SSAA09E1
CAS:SSAA09E1 blocks SARS-CoV entry, lowers ACE2-mediated HEK293T cell infection (EC50 = 6.7 μM), and inhibits cathepsin L (IC50 = 5.33 μM).Fórmula:C7H9N3S2Forma y color:SolidPeso molecular:199.3MDL 27399
CAS:MDL 27399 suppresses human neutrophil cathepsin G.Fórmula:C26H36N4O8Forma y color:SolidPeso molecular:532.59Cathepsin L/S-IN-1
Cathepsin L/S-IN-1 inhibits Cathepsin L & S (IC50: 4.10 & 1.79 μM) and reduces metastasis in pancreatic cancer cells.Fórmula:C29H33BrN4O4SForma y color:SolidPeso molecular:613.57JPM-OEt
CAS:JPM-OEt: broad-spectrum, covalent cysteine cathepsin inhibitor with antitumor effects.Fórmula:C20H28N2O6Pureza:98%Forma y color:SolidPeso molecular:392.45L-873724
CAS:L-873724: Selective, reversible cathepsin K inhibitor; IC50s—cat K: 0.2 nM, cat S: 178 nM, cat L: 264 nM, cat B: 5239 nM; inhibits bone resorption.Fórmula:C23H26F3N3O3SPureza:98%Forma y color:SolidPeso molecular:481.53SAP2-IN-1
CAS:SAP2-IN-1 inhibits secreted aspartate protease 2 (IC50: 0.92 μM), doesn't work in vitro, and helps research infections.Fórmula:C34H29NO7Forma y color:SolidPeso molecular:563.6SJA6017
CAS:SJA6017: inhibits calpain-1/2, cathepsins B/L; prevents apoptosis, protects spinal cord, boosts function. IC50s: 7.5-78 nM.Fórmula:C17H25FN2O4SPureza:98%Forma y color:SolidPeso molecular:372.45A-933548
CAS:A-933548: potent calpain inhibitor, selective vs. cathepsins, stable, effective in cell assays.Fórmula:C25H21N5O3Pureza:98%Forma y color:SolidPeso molecular:439.47Cysteine Protease inhibitor hydrochloride
CAS:Cysteine Protease inhibitor hydrochloride is a cysteine protease inhibitor.Fórmula:C18H15ClN4OPureza:98%Forma y color:SolidPeso molecular:338.79Cysteine protease inhibitor-2
CAS:Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.Fórmula:C13H5N5OPureza:98%Forma y color:SolidPeso molecular:247.21ASPER-29
CAS:ASPER-29, an Asperphenamate analog, inhibits cathepsins L/S with IC50s of 6.03/5.02 μM, useful in cancer migration/invasion research.Fórmula:C31H29BrN2O5SForma y color:SolidPeso molecular:621.54VEL-0230
CAS:VEL-0230 (NC-2300) is a cathespin K inhibitor boosting bone growth and reducing loss, targeting bone diseases and developed by Velcura Therapeutics.Fórmula:C14H24NNaO5Forma y color:SolidPeso molecular:309.33Dutacatib
CAS:Dutacatib is an inhibitor of SARS-CoV-2 3CLpro and cathepsin K, offering antiviral properties and potential benefits in treating cancer-induced bone disease.Fórmula:C23H31N7OForma y color:SolidPeso molecular:421.54GSK-2793660
CAS:GSK-2793660, an oral, irreversible CTSC inhibitor, aids bronchiectasis research.Fórmula:C20H27N3O3Pureza:98%Forma y color:SolidPeso molecular:357.45Kgp-IN-1
CAS:Kgp-IN-1 is an arginine-specific gingipain (Rgp) inhibitor.Fórmula:C19H24F4N4O3Pureza:98%Forma y color:SolidPeso molecular:432.41Gü2602
CAS:Gü2602 inhibits the cathepsin K zymogen autocatalytic activation that is a potent, reversible inhibitor of cathepsin K (CatK) with a Ki of 0.013 nM for matureFórmula:C16H22N4O3Forma y color:SolidPeso molecular:318.37LHVS
CAS:LHVS effectively blocks T.Fórmula:C28H37N3O5SPureza:98%Forma y color:SolidPeso molecular:527.68
