Cisteína proteasa
Los inhibidores de proteasas de cisteína son compuestos que se dirigen e inhiben a las proteasas de cisteína, una clase de enzimas que descomponen proteínas al romper enlaces peptídicos en los que un residuo de cisteína actúa como nucleófilo. Estas enzimas están involucradas en varios procesos fisiológicos, como la apoptosis, la respuesta inmune y el recambio de proteínas. Los inhibidores de proteasas de cisteína son fundamentales para estudiar enfermedades como el cáncer, los trastornos neurodegenerativos y las infecciones parasitarias. En CymitQuimica, ofrecemos inhibidores de proteasas de cisteína para apoyar su investigación en proteólisis, regulación celular y descubrimiento de fármacos.
Se han encontrado 110 productos de "Cisteína proteasa"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CatD-IN-1
CAS:CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM, and it shows potential for research in the field of osteoarthritis.Fórmula:C18H18Cl2N4O5Forma y color:SolidPeso molecular:441.265GB111-NH2
CAS:GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].Fórmula:C33H39N3O6Forma y color:SolidPeso molecular:573.68Verducatib
CAS:Verducatib is an inhibitor of cathepsins (cathepsin).Fórmula:C31H35FN4O3Forma y color:SolidPeso molecular:530.633Z-FY-CHO
CAS:Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.Fórmula:C26H26N2O5Pureza:95.88%Forma y color:SolidPeso molecular:446.5Cathepsin C-IN-5
CAS:<p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>Fórmula:C21H17ClN6OSForma y color:SolidPeso molecular:436.92Dual Cathepsin L/JAK-IN-1
CAS:DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 μM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-κB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).Fórmula:C19H18ClN5Forma y color:SolidPeso molecular:351.833Z-Val-Val-Nle-diazomethylketone
CAS:Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS). It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.Fórmula:C25H37N5O5Forma y color:SolidPeso molecular:487.59MIV-247
CAS:MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.Fórmula:C17H24F3N3O4Pureza:99.27%Forma y color:SolidPeso molecular:391.39PD 151746
CAS:PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.Fórmula:C11H8FNO2SPureza:98.63% - ≥95%Forma y color:SolidPeso molecular:237.25ALLM
CAS:ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].Fórmula:C19H35N3O4SPureza:98%Forma y color:White PowderPeso molecular:401.56
