Receptor activado por proteasa
Los inhibidores del Receptor Activado por Proteasas (PAR) son compuestos que se dirigen e inhiben la actividad de los PARs, una familia de receptores acoplados a proteínas G que se activan por escisión proteolítica. Estos receptores desempeñan un papel en diversos procesos fisiológicos, incluidos la coagulación, la inflamación y la reparación de tejidos. Los inhibidores de PAR son herramientas valiosas para estudiar los mecanismos de estos procesos y su implicación en enfermedades como el cáncer, trastornos cardiovasculares y la inflamación crónica. En CymitQuimica, ofrecemos inhibidores de PAR para apoyar su investigación en transducción de señales, respuesta inmunitaria y descubrimiento terapéutico.
Se han encontrado 55 productos para "Receptor activado por proteasa".
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Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].Fórmula:C193H331F3N64O55S3Forma y color:SolidPeso molecular:4581.28TRAP-6 amide
CAS:TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.Fórmula:C34H57N11O8Forma y color:SolidPeso molecular:747.899RAG8 peptide
RAG8 peptide is an antagonist of protease-activated receptor 4 (PAR 4), which inhibits late-stage platelet activation and reduces thrombosis without altering hemostasis or increasing bleeding risk. It is applicable in atherosclerosis research.Fórmula:C56H98N16O11Forma y color:SolidPeso molecular:1170.7601PAR-4 Agonist Peptide, amide acetate
PAR-4 Agonist Peptide, amide acetate is an agonist of proteinase-activated receptor-4 (PAR-4).Fórmula:C36H52N8O9Pureza:98%Forma y color:SolidPeso molecular:740.86H-Ser-Phe-Leu-Leu-Arg-OH
CAS:Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5), used in the research of coronary heart disease (CHD).Fórmula:C30H50N8O7Pureza:98%Forma y color:SolidPeso molecular:634.77PAR-4 Agonist Peptide, amide
CAS:PAR-4 Agonist Peptide, amide (AY-NH2) is an agonist of proteinase-activated receptor-4 (PAR-4).Fórmula:C34H48N8O7Pureza:98%Forma y color:SolidPeso molecular:680.79AC-264613
CAS:AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.Fórmula:C19H18BrN3O2Pureza:98%Forma y color:SolidPeso molecular:400.28TFLLR-NH2(TFA)
CAS:TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM. EC50: 1.9 μM (PAR1)Fórmula:C33H54F3N9O8Pureza:98%Forma y color:SolidPeso molecular:761.83SLIGRL-NH2
CAS:SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.Fórmula:C29H56N10O7Pureza:98.29%Forma y color:White SolidPeso molecular:656.82Vorapaxar
CAS:Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).Fórmula:C29H33FN2O4Pureza:98.77% - 99.93%Forma y color:White SolidPeso molecular:492.58Ref: TM-T7013
1mg71,00€5mg138,00€1mL*10mM (DMSO)152,00€10mg192,00€25mg326,00€50mg447,00€100mg642,00€200mg888,00€tcY-NH2 TFA(327177-34-4 free base)
tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.Fórmula:C42H50F3N7O9Pureza:99.88%Forma y color:SolidPeso molecular:853.9FSLLRY-NH2 TFA(245329-02-6 free base)
FSLLRY-NH2 TFA inhibits PAR2, reverses taxol-induced pain, and reduces itch in mice; blocks ERK and collagen in fibroblasts.Fórmula:C41H61F3N10O10Pureza:99.32%Forma y color:SolidPeso molecular:910.99PAR-2-IN-1
CAS:PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.Fórmula:C12H14ClN3O2Pureza:99.75%Forma y color:White SolidPeso molecular:267.71Ref: TM-T8917
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg86,00€25mg161,00€50mg243,00€100mg355,00€200mg502,00€Protease-Activated Receptor-2, amide
CAS:Protease-Activated Receptor-2, amide (SLIGKV-NH2) is an agonist of PAR2 (IC50 : 10.4 M)Fórmula:C28H54N8O7Pureza:>99.99%Forma y color:SolidPeso molecular:614.782-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.Fórmula:C38H64F3N11O10Pureza:>99.99%Forma y color:White SolidPeso molecular:891.98VKGILS-NH2 Acetate
VKGILS-NH2 Acetate is a reversed amino acid sequence control peptide for SLIGKV-NH2, a protease-activated receptor 2 (PAR2) agonist.Fórmula:C30H58N8O9Pureza:98.83%Forma y color:SolidPeso molecular:674.83Ref: TM-T21699L
1mg33,00€2mg49,00€5mg62,00€10mg92,00€1mL*10mM (DMSO)92,00€25mg155,00€50mg224,00€100mg331,00€200mg470,00€Parmodulin 2
CAS:ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).Fórmula:C17H17BrN2O2Pureza:97.35% - 99.95%Forma y color:SolidPeso molecular:361.23LRGILS-NH2 acetate
LRGILS-NH2 acetate is a PAR-2-inactive reversed peptide.Fórmula:C29H56N10O7Pureza:96.65%Forma y color:SolidPeso molecular:656.82TFLLR-NH2 2TFA(197794-83-5(free base))
TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).Fórmula:C35H55F6N9O10Pureza:99.56%Forma y color:SolidPeso molecular:875.87Vorapaxar sulfate
CAS:Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.Fórmula:C29H35FN2O8SPureza:99.9% - >99.99%Forma y color:White SolidPeso molecular:590.66Ref: TM-T3098
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)94,00€10mg113,00€25mg200,00€50mg334,00€100mg500,00€500mg1.099,00€
