Receptor activado por proteasa
Los inhibidores del Receptor Activado por Proteasas (PAR) son compuestos que se dirigen e inhiben la actividad de los PARs, una familia de receptores acoplados a proteínas G que se activan por escisión proteolítica. Estos receptores desempeñan un papel en diversos procesos fisiológicos, incluidos la coagulación, la inflamación y la reparación de tejidos. Los inhibidores de PAR son herramientas valiosas para estudiar los mecanismos de estos procesos y su implicación en enfermedades como el cáncer, trastornos cardiovasculares y la inflamación crónica. En CymitQuimica, ofrecemos inhibidores de PAR para apoyar su investigación en transducción de señales, respuesta inmunitaria y descubrimiento terapéutico.
Se han encontrado 54 productos de "Receptor activado por proteasa"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
FSLLRY-NH2 TFA(245329-02-6 free base)
<p>FSLLRY-NH2 TFA inhibits PAR2, reverses taxol-induced pain, and reduces itch in mice; blocks ERK and collagen in fibroblasts.</p>Fórmula:C41H61F3N10O10Pureza:99.32%Forma y color:SolidPeso molecular:910.99tcY-NH2 TFA(327177-34-4 free base)
<p>tcY-NH2 TFA is a selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.</p>Fórmula:C42H50F3N7O9Pureza:>99.99%Forma y color:SolidPeso molecular:853.9Thrombin Receptor Activator for Peptide
<p>Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.</p>Fórmula:C32H51F3N8O9Pureza:99.88%Forma y color:SolidPeso molecular:748.79Parmodulin 2
CAS:<p>ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).</p>Fórmula:C17H17BrN2O2Pureza:97.35% - 99.95%Forma y color:SolidPeso molecular:361.23AZ3451
CAS:<p>AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).</p>Fórmula:C30H27BrN4O3Pureza:98.12%Forma y color:SolidPeso molecular:571.46Protease-Activated Receptor-4 diTFA
<p>Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist</p>Fórmula:C37H48F6N8O11Pureza:98.54%Forma y color:SolidPeso molecular:894.812-Furoyl-LIGRLO-amide TFA(729589-58-6 free base)
<p>2-Furoyl-LIGRLO-amide TFA(729589-58-6 free base) is a potent and selective protease-activated receptor 2 (PAR2) agonist.</p>Fórmula:C38H64F3N11O10Pureza:>99.99%Forma y color:SolidPeso molecular:891.98ML-354
CAS:<p>ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].</p>Fórmula:C16H14N2O3Pureza:99.44%Forma y color:SolidPeso molecular:282.29iso-TRAP-6
CAS:<p>iso-TRAP-6 (iso-SFLLRN), a hexapeptide made from isoserine instead of serine, is a PAR1 agonist that activates platelets via PAR-1.</p>Fórmula:C34H56N10O9Pureza:98.55%Forma y color:SolidPeso molecular:748.87PAR4 antagonist 3
CAS:<p>PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4). It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.</p>Fórmula:C22H16FN3O5SPeso molecular:453.44PAR-2-IN-2
CAS:<p>PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 μM for SLIGKV and an IC50 greater than 200 μM for trypsin.</p>Fórmula:C25H20F3N5O2Forma y color:SolidPeso molecular:479.454BMS-986141
CAS:<p>BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614</p>Fórmula:C27H23N5O5S2Pureza:98.43% - 99.26%Forma y color:SolidPeso molecular:561.63Protease-Activated Receptor-4
CAS:<p>Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.</p>Fórmula:C33H46N8O7Pureza:98%Forma y color:SolidPeso molecular:666.77TFLLR-NH2 2TFA(197794-83-5(free base))
<p>TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).</p>Fórmula:C35H55F6N9O10Pureza:99.56%Forma y color:SolidPeso molecular:875.87
