VEGFR
Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 268 productos de "VEGFR"
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Cabozantinib S-malate
CAS:<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Fórmula:C32H30FN3O10Pureza:98% - >99.99%Forma y color:SolidPeso molecular:635.59SU5214
CAS:<p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>Fórmula:C16H13NO2Pureza:99.45% - 99.55%Forma y color:SolidPeso molecular:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
<p>UNC0064-12 hydrochloride is an inhibitor of VEGFR2.</p>Fórmula:C19H25ClN8Pureza:99.52%Forma y color:SolidPeso molecular:400.91Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45Ramucirumab
CAS:<p>Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.</p>Fórmula:C285H434N74O88S2Pureza:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Forma y color:LiquidPeso molecular:143.77 kDaNingetinib
CAS:<p>Ningetinib (CT-053) (CT053PTSA) is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Fórmula:C31H29FN4O5Pureza:99.95% - 99.98%Forma y color:SolidPeso molecular:556.58Orobol
CAS:<p>Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.</p>Fórmula:C15H10O6Pureza:98% - 98%Forma y color:SolidPeso molecular:286.24XL 999
CAS:<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Fórmula:C26H28FN5OPureza:98.24% - 99.55%Forma y color:SolidPeso molecular:445.53Cabozantinib
CAS:<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Fórmula:C28H24FN3O5Pureza:99.68% - 99.88%Forma y color:SolidPeso molecular:501.51BFH772
CAS:<p>BFH772, a BAW2881 analogue, selectively inhibits VEGFR2 (IC50: 3 nM) and blocks RET, PDGFR, KIT phosphorylation (IC50: 30-160 nM).</p>Fórmula:C23H16F3N3O3Pureza:97.71% - 99.36%Forma y color:SolidPeso molecular:439.39Su1498
CAS:<p>Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the VEGF receptor 2, having negligible activity at several other serine/threonine and tyrosine kinases.</p>Fórmula:C25H30N2O2Pureza:99.54%Forma y color:SolidPeso molecular:390.52Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Fórmula:C21H16Cl2F4N4O3Pureza:99.56%Forma y color:SolidPeso molecular:519.28Tesevatinib
CAS:<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Forma y color:SolidPeso molecular:491.39NVP-ACC789
CAS:<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Fórmula:C21H17BrN4Pureza:99.44% - 99.63%Forma y color:SolidPeso molecular:405.29Alectinib
CAS:<p>Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H34N4O2Pureza:98% - 99.38%Forma y color:SolidPeso molecular:482.62BMS-2
CAS:<p>BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.</p>Fórmula:C25H16F2N4O3Pureza:98.33%Forma y color:SolidPeso molecular:458.42Nintedanib
CAS:<p>Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/</p>Fórmula:C31H33N5O4Pureza:98% - 99.92%Forma y color:SolidPeso molecular:539.62Mollugin
CAS:Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Fórmula:C17H16O4Pureza:99.87% - ≥95%Forma y color:SolidPeso molecular:284.31Cabozantinib hydrochloride
CAS:<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Fórmula:C28H25ClFN3O5Pureza:99.97%Forma y color:SolidPeso molecular:537.96JK-P3
CAS:<p>JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.</p>Fórmula:C18H17N3O3Pureza:99.57%Forma y color:SolidPeso molecular:323.35Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Fórmula:C21H21FN6OPureza:99.35% - 99.92%Forma y color:SolidPeso molecular:392.43ODM-203
CAS:<p>ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity</p>Fórmula:C26H21F2N5O2SPureza:99.85%Forma y color:SolidPeso molecular:505.54Sitravatinib
CAS:<p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>Fórmula:C33H29F2N5O4SPureza:98.9% - 99.85%Forma y color:SolidPeso molecular:629.684SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Fórmula:C33H38N8O4SPureza:96.4% - 99.67%Forma y color:SolidPeso molecular:642.77hVEGF-IN-1
CAS:<p>hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.</p>Fórmula:C34H43N7O2Pureza:99.76% - >99.99%Forma y color:SolidPeso molecular:581.75ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47SPHINX31
CAS:<p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>Fórmula:C27H24F3N5O2Pureza:98.81% - 99.3%Forma y color:SolidPeso molecular:507.51AST 487
CAS:<p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>Fórmula:C26H30F3N7O2Pureza:98.17% - 99.56%Forma y color:SolidPeso molecular:529.56Tivozanib hydrochloride hydrate
CAS:<p>Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .</p>Fórmula:C22H22Cl2N4O6Pureza:98.66%Forma y color:SolidPeso molecular:509.34Toceranib
CAS:<p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>Fórmula:C22H25FN4O2Pureza:97.14%Forma y color:SolidPeso molecular:396.46(Rac)-SAR131675
CAS:<p>(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.</p>Fórmula:C18H22N4O4Pureza:98.34% - 99.1%Forma y color:SolidPeso molecular:358.39BIBF 1202
CAS:<p>BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).</p>Fórmula:C30H31N5O4Pureza:98.04%Forma y color:SolidPeso molecular:525.6BMS-690514
CAS:<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Fórmula:C19H24N6O2Pureza:99.08%Forma y color:SolidPeso molecular:368.43Brivanib (alaninate)
CAS:<p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>Fórmula:C22H24FN5O4Pureza:99.46% - 99.66%Forma y color:SolidPeso molecular:441.46Anti-Mouse VEGFR-2 Antibody (DC101)
<p>Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.</p>Pureza:99%Forma y color:Odour LiquidTarcocimab
CAS:<p>Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.</p>Forma y color:LiquidZM323881 hydrochloride
CAS:<p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>Fórmula:C22H19ClFN3O2Pureza:99.43%Forma y color:SolidPeso molecular:411.86Dovitinib Dilactic Acid
CAS:<p>Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.</p>Fórmula:C21H21FN6O·2C3H6O3Pureza:98%Forma y color:SolidPeso molecular:572.59Bucillamine
CAS:<p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>Fórmula:C7H13NO3S2Pureza:99.47%Forma y color:SolidPeso molecular:223.31E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Forma y color:SolidPeso molecular:378.46GW843682X
CAS:<p>GW843682X (GW843682) is a selective and ATP-competitive inhibitor of PLK1 and PLK3 (IC50s = 2.2 nM and 9.1 nM).</p>Fórmula:C22H18F3N3O4SPureza:99.92%Forma y color:SolidPeso molecular:477.46CP-547632
CAS:<p>CP-547632 is an oral ATP-competitive inhibitor of VEGFR-2/FGF kinase with IC50s of 11/9 nM, highly selective, has antitumor activity.</p>Fórmula:C20H24BrF2N5O3SPureza:99.39%Forma y color:SolidPeso molecular:532.4DMH4
CAS:<p>DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.</p>Fórmula:C24H24N4O2Pureza:99.58%Forma y color:SolidPeso molecular:400.47AMG-Tie2-1
CAS:<p>AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.</p>Fórmula:C25H20F3N5O2Pureza:98.9%Forma y color:SolidPeso molecular:479.45VEGFR-2-IN-6
CAS:<p>VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].</p>Fórmula:C20H21N7O2SPureza:99.01%Forma y color:SolidPeso molecular:423.49MMPP
CAS:<p>MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.</p>Fórmula:C17H18O3Pureza:99.31% - 99.83%Forma y color:SolidPeso molecular:270.32Naphazoline
CAS:<p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>Fórmula:C14H14N2Pureza:99.79%Forma y color:White Crystalline Powder SolidPeso molecular:210.27Ansornitinib
CAS:<p>Ansornitinib (ANG-3070) is a KDR and PDGF receptor inhibitor with antifibrotic activity for the study of diseases caused by abnormal or excessive fibrosis.</p>Fórmula:C30H32N6O4Forma y color:SolidPeso molecular:540.61CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Fórmula:C18H18ClN5OPureza:98.81%Forma y color:SolidPeso molecular:355.82AMPK-IN-3
CAS:<p>AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.</p>Fórmula:C25H33N5O3Pureza:99.13%Forma y color:SolidPeso molecular:451.56VEGFR-3-IN-1
CAS:<p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>Fórmula:C29H29ClF3N7OSPureza:99.95%Forma y color:SolidPeso molecular:616.1Pz-1
CAS:<p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>Fórmula:C26H26N6O2Pureza:99.89%Forma y color:SolidPeso molecular:454.52Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47(Z)-FeCP-oxindole
CAS:<p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>Fórmula:C19H15FeNOPureza:99.63% - 99.84%Forma y color:SolidPeso molecular:329.17(E)-FeCP-oxindole
CAS:<p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。</p>Fórmula:C19H15FeNOPureza:99.85%Forma y color:SolidPeso molecular:329.17Tyrphostin AG1433
CAS:<p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>Fórmula:C16H14N2O2Pureza:98.47%Forma y color:SolidPeso molecular:266.29TIE-2/VEGFR-2 kinase-IN-5
CAS:<p>TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.</p>Fórmula:C21H13F6N5O2Pureza:99.79%Forma y color:SolidPeso molecular:481.35Brolucizumab
CAS:<p>Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.</p>Pureza:95%Forma y color:LiquidTG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Fórmula:C26H27Cl2N5O2Pureza:98%Forma y color:SolidPeso molecular:512.43AKB-6899
CAS:<p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>Fórmula:C14H11FN2O4Pureza:97.87%Forma y color:SolidPeso molecular:290.25VEGFR-2-IN-9
CAS:<p>VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.</p>Fórmula:C23H25N3O3Pureza:97.19%Forma y color:SolidPeso molecular:391.46VEGFR-2-IN-37
CAS:<p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>Fórmula:C18H16N2O2SPureza:98%Forma y color:SolidPeso molecular:324.4VEGFR2-IN-3
CAS:<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Fórmula:C26H28ClN5O4Pureza:98%Forma y color:SolidPeso molecular:509.98WAY-600
CAS:<p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>Fórmula:C28H30N8OPureza:99.88%Forma y color:SolidPeso molecular:494.59VEGFR2-IN-1
CAS:<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Fórmula:C22H18N6SPureza:98.15%Forma y color:SolidPeso molecular:398.48Lucitanib dihydrochloride
CAS:<p>Lucitanib dihydrochloride (E-3810 dihydrochloride) is an efficient VEGFR1-3, FGFR1-3, and PDGFRalpha/β inhibitor, used in metastatic breast cancer research.</p>Fórmula:C26H27Cl2N3O4Forma y color:SolidPeso molecular:516.42VEGFR/PDGFR-IN-1
CAS:<p>VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.</p>Fórmula:C17H21N5O3Forma y color:SolidPeso molecular:343.38VEGFR-2-IN-65
CAS:<p>VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.</p>Fórmula:C21H18N2O3Forma y color:SolidPeso molecular:346.379
