VEGFR
Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 267 productos de "VEGFR"
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VEGFR-2-IN-5
CAS:<p>VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.</p>Fórmula:C19H24N8Pureza:99.92%Forma y color:SolidPeso molecular:364.45BMS-794833
CAS:<p>BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2; a prodrug of BMS-817378.</p>Fórmula:C23H15ClF2N4O3Pureza:98% - 99.69%Forma y color:SolidPeso molecular:468.84Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Forma y color:SolidPeso molecular:469.94ZD-4190
CAS:<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Fórmula:C19H16BrFN6O2Pureza:99.12%Forma y color:SolidPeso molecular:459.27SKLB1002
CAS:<p>SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.</p>Fórmula:C13H12N4O2S2Pureza:98.51% - >99.99%Forma y color:SolidPeso molecular:320.39Lenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Forma y color:SolidPeso molecular:522.96PF 477736
CAS:<p>PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (</p>Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:SolidPeso molecular:443.44Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Forma y color:SolidPeso molecular:500.83VEGFR2-IN-2
CAS:<p>VEGFR2-IN-2 has anti-inflammatory and analgesic activities.</p>Fórmula:C15H11BrN2OPureza:99.504%Forma y color:SolidPeso molecular:315.16Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Forma y color:SolidPeso molecular:510.36XL092
CAS:<p>XL092 (JUN04542) is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.</p>Fórmula:C29H25FN4O5Pureza:98.60%Forma y color:SolidPeso molecular:528.53TAK-659 hydrochloride
CAS:<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Forma y color:SolidPeso molecular:380.85CP-673451
CAS:<p>CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other</p>Fórmula:C24H27N5O2Pureza:99.62% - 99.88%Forma y color:SolidPeso molecular:417.5(Z)-Guggulsterone
CAS:<p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>Fórmula:C21H28O2Pureza:98.93% - 99.72%Forma y color:SolidPeso molecular:312.45Tanshinone IIA
CAS:<p>Tanshinone IIA (Tanshinone B) is a natural diterpene quinone. Tanshinone IIA has anti-inflammatory, antioxidant activities. Cost-effective and quality-assured.</p>Fórmula:C19H18O3Pureza:99.04% - >99.99%Forma y color:Cherry CrystalPeso molecular:294.34Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Fórmula:C24H27FN6O4Pureza:99.82%Forma y color:SolidPeso molecular:482.51Takeda-6d
CAS:<p>Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.</p>Fórmula:C27H19ClFN5O3SPureza:98.27%Forma y color:SolidPeso molecular:547.99AZD4547
CAS:<p>AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.</p>Fórmula:C26H33N5O3Pureza:99.37% - 99.88%Forma y color:SolidPeso molecular:463.57Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Fórmula:C22H24BrFN4O2Pureza:99.7% - >99.99%Forma y color:White SolidPeso molecular:475.35
