VEGFR
Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 268 productos de "VEGFR"
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VEGFR-3-IN-1
CAS:<p>VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.</p>Fórmula:C29H29ClF3N7OSPureza:99.95%Forma y color:SolidPeso molecular:616.1Pz-1
CAS:<p>Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.</p>Fórmula:C26H26N6O2Pureza:99.89%Forma y color:SolidPeso molecular:454.52Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47(Z)-FeCP-oxindole
CAS:<p>(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.</p>Fórmula:C19H15FeNOPureza:99.63% - 99.84%Forma y color:SolidPeso molecular:329.17(E)-FeCP-oxindole
CAS:<p>(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。</p>Fórmula:C19H15FeNOPureza:99.85%Forma y color:SolidPeso molecular:329.17Tyrphostin AG1433
CAS:<p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>Fórmula:C16H14N2O2Pureza:98.47%Forma y color:SolidPeso molecular:266.29TIE-2/VEGFR-2 kinase-IN-5
CAS:<p>TIE-2/VEGFR-2 kinase-IN-5 is a TIE-2 and VEGFR-2 tyrosine kinase receptor inhibitor commonly used in biomedical research related to angiogenesis.</p>Fórmula:C21H13F6N5O2Pureza:99.79%Forma y color:SolidPeso molecular:481.35Brolucizumab
CAS:<p>Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.</p>Pureza:95%Forma y color:LiquidTG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Fórmula:C26H27Cl2N5O2Pureza:98%Forma y color:SolidPeso molecular:512.43AKB-6899
CAS:<p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>Fórmula:C14H11FN2O4Pureza:97.87%Forma y color:SolidPeso molecular:290.25VEGFR-2-IN-9
CAS:<p>VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.</p>Fórmula:C23H25N3O3Pureza:97.19%Forma y color:SolidPeso molecular:391.46VEGFR-2-IN-37
CAS:<p>VEGFR-2-IN-37 (compound 12), a VEGFR-2 inhibitor, exhibits an inhibition rate of approximately 56.9 μM at a concentration of 200 μM.</p>Fórmula:C18H16N2O2SPureza:98%Forma y color:SolidPeso molecular:324.4VEGFR2-IN-3
CAS:<p>VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].</p>Fórmula:C26H28ClN5O4Pureza:98%Forma y color:SolidPeso molecular:509.98WAY-600
CAS:<p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>Fórmula:C28H30N8OPureza:99.88%Forma y color:SolidPeso molecular:494.59VEGFR2-IN-1
CAS:<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Fórmula:C22H18N6SPureza:98.15%Forma y color:SolidPeso molecular:398.48Lucitanib dihydrochloride
CAS:<p>Lucitanib dihydrochloride (E-3810 dihydrochloride) is an efficient VEGFR1-3, FGFR1-3, and PDGFRalpha/β inhibitor, used in metastatic breast cancer research.</p>Fórmula:C26H27Cl2N3O4Forma y color:SolidPeso molecular:516.42VEGFR/PDGFR-IN-1
CAS:<p>VEGFR/PDGFR-IN-1 (Compound 1) is an inhibitor of VEGFR with an IC50 of 0.4 μM. It can inhibit angiogenesis in HUVEC cells and holds promise for impeding tumor growth and metastasis.</p>Fórmula:C17H21N5O3Forma y color:SolidPeso molecular:343.38VEGFR-2-IN-65
CAS:<p>VEGFR-2-IN-65 (Compound 07) functions as a VEGFR-2 inhibitor. It forms hydrogen bonds with Cys180 and can inhibit tube formation in HUVECs.</p>Fórmula:C21H18N2O3Forma y color:SolidPeso molecular:346.379
