VEGFR
Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 262 productos de "VEGFR"
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EOC317
CAS:<p>EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).</p>Fórmula:C27H26F5N7O3Pureza:98.00% - 99.26%Forma y color:SolidPeso molecular:591.53SU5208
CAS:<p>SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).</p>Fórmula:C13H9NOSPureza:99.62%Forma y color:SolidPeso molecular:227.28Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Fórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:SolidPeso molecular:375.4Semaxinib
CAS:<p>Semaxinib (SU5416): potent VEGFR2 inhibitor, 20x more selective over PDGFRβ, not active on InsR/EGFR/FGFR, blocks ATP on VEGFR2, may reduce tumor vessels.</p>Fórmula:C15H14N2OPureza:99.84%Forma y color:Yellow To Yellow OrangePeso molecular:238.28GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Fórmula:C17H16N2OPureza:>99.99%Forma y color:SolidPeso molecular:264.32PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Forma y color:SolidPeso molecular:319.36KI8751
CAS:<p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Forma y color:SolidPeso molecular:469.41Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Fórmula:C20H15ClN4·2HClPureza:99.16%Forma y color:White To Off-White Crystalline PowderPeso molecular:419.73ZD-4190
CAS:<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Fórmula:C19H16BrFN6O2Pureza:99.12%Forma y color:SolidPeso molecular:459.27Golvatinib
CAS:<p>Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor</p>Fórmula:C33H37F2N7O4Pureza:98.24% - ≥95%Forma y color:SolidPeso molecular:633.69Ningetinib Tosylate
CAS:<p>Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.</p>Fórmula:C38H37FN4O8SPureza:99.93%Forma y color:SolidPeso molecular:728.79Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56Cabozantinib S-malate
CAS:<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Fórmula:C32H30FN3O10Pureza:98% - >99.99%Forma y color:SolidPeso molecular:635.59Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Forma y color:SolidPeso molecular:244.29SU5214
CAS:<p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>Fórmula:C16H13NO2Pureza:99.45% - 99.55%Forma y color:SolidPeso molecular:251.28UNC0064-12 hydrochloride (1430089-64-7(free base))
<p>UNC0064-12 hydrochloride is an inhibitor of VEGFR2.</p>Fórmula:C19H25ClN8Pureza:99.52%Forma y color:SolidPeso molecular:400.91Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45Ramucirumab
CAS:<p>Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.</p>Fórmula:C285H434N74O88S2Pureza:98.2% (SDS-PAGE); 99.2% (SEC-HPLC) - 99.20%Forma y color:LiquidPeso molecular:143.77 kDaBevacizumab
CAS:<p>Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.</p>Pureza:95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Forma y color:LiquidPeso molecular:146.53 kDa
