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VEGFR

VEGFR

Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.

Se han encontrado 268 productos de "VEGFR"

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  • Dovitinib

    CAS:
    <p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>
    Fórmula:C21H21FN6O
    Pureza:99.35% - 99.92%
    Forma y color:Solid
    Peso molecular:392.43
  • ODM-203

    CAS:
    <p>ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity</p>
    Fórmula:C26H21F2N5O2S
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:505.54
  • Sitravatinib

    CAS:
    <p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>
    Fórmula:C33H29F2N5O4S
    Pureza:98.9% - 99.85%
    Forma y color:Solid
    Peso molecular:629.68
  • 4SC-203

    CAS:
    <p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>
    Fórmula:C33H38N8O4S
    Pureza:96.4% - 99.67%
    Forma y color:Solid
    Peso molecular:642.77
  • hVEGF-IN-1

    CAS:
    <p>hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.</p>
    Fórmula:C34H43N7O2
    Pureza:99.76% - >99.99%
    Forma y color:Solid
    Peso molecular:581.75
  • ENMD-2076

    CAS:
    <p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>
    Fórmula:C21H25N7
    Pureza:97.63% - ≥95%
    Forma y color:Solid
    Peso molecular:375.47
  • SPHINX31

    CAS:
    <p>SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).</p>
    Fórmula:C27H24F3N5O2
    Pureza:98.81% - 99.3%
    Forma y color:Solid
    Peso molecular:507.51
  • AST 487

    CAS:
    <p>AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.</p>
    Fórmula:C26H30F3N7O2
    Pureza:98.17% - 99.56%
    Forma y color:Solid
    Peso molecular:529.56
  • Tivozanib hydrochloride hydrate

    CAS:
    <p>Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is a VEGFR tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, VEGFR-3 .</p>
    Fórmula:C22H22Cl2N4O6
    Pureza:98.66%
    Forma y color:Solid
    Peso molecular:509.34
  • Toceranib

    CAS:
    <p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>
    Fórmula:C22H25FN4O2
    Pureza:97.14%
    Forma y color:Solid
    Peso molecular:396.46
  • (Rac)-SAR131675

    CAS:
    <p>(Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor, which inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells.</p>
    Fórmula:C18H22N4O4
    Pureza:98.34% - 99.1%
    Forma y color:Solid
    Peso molecular:358.39
  • BIBF 1202

    CAS:
    <p>BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).</p>
    Fórmula:C30H31N5O4
    Pureza:98.04%
    Forma y color:Solid
    Peso molecular:525.6
  • BMS-690514

    CAS:
    <p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>
    Fórmula:C19H24N6O2
    Pureza:99.08%
    Forma y color:Solid
    Peso molecular:368.43
  • Brivanib (alaninate)

    CAS:
    <p>Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.</p>
    Fórmula:C22H24FN5O4
    Pureza:99.46% - 99.66%
    Forma y color:Solid
    Peso molecular:441.46
  • Anti-Mouse VEGFR-2 Antibody (DC101)


    <p>Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.</p>
    Pureza:99%
    Forma y color:Odour Liquid
  • Tarcocimab

    CAS:
    <p>Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.</p>
    Forma y color:Liquid
  • ZM323881 hydrochloride

    CAS:
    <p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>
    Fórmula:C22H19ClFN3O2
    Pureza:99.43%
    Forma y color:Solid
    Peso molecular:411.86
  • Dovitinib Dilactic Acid

    CAS:
    <p>Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.</p>
    Fórmula:C21H21FN6O·2C3H6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:572.59
  • Bucillamine

    CAS:
    <p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>
    Fórmula:C7H13NO3S2
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:223.31
  • E3330

    CAS:
    <p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>
    Fórmula:C21H30O6
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:378.46