VEGFR
Los inhibidores del receptor del factor de crecimiento endotelial vascular (VEGFR) son compuestos que bloquean la señalización del VEGFR, un receptor clave en la vía del VEGF, crucial para la angiogénesis. Los inhibidores del VEGFR impiden la formación de nuevos vasos sanguíneos que suministran nutrientes y oxígeno a los tumores, inhibiendo así el crecimiento tumoral. Estos inhibidores se utilizan ampliamente en la terapia contra el cáncer y en la investigación para estudiar los mecanismos de la angiogénesis y desarrollar tratamientos anticancerígenos. En CymitQuimica, ofrecemos una gama completa de inhibidores de VEGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 268 productos de "VEGFR"
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Albendazole
CAS:<p>Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.</p>Fórmula:C12H15N3O2SPureza:98.21% - 98.76%Forma y color:Colorless Crystals SolidPeso molecular:265.33PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Fórmula:C25H20Cl2N2O3Pureza:99.72%Forma y color:SolidPeso molecular:467.34Axitinib
CAS:<p>Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C22H18N4OSPureza:98.9% - 99.74%Forma y color:Off-White SolidPeso molecular:386.472H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS:Fórmula:C15H14N2OPureza:98%Forma y color:SolidPeso molecular:238.2845Naphazoline hydrochloride
CAS:<p>Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.</p>Fórmula:C14H15ClN2Pureza:97.93%Forma y color:White Crystalline Powder White Crystalline PowderPeso molecular:246.74GW806742X
CAS:<p>GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.</p>Fórmula:C25H22F3N7O4SPureza:98.3%Forma y color:SolidPeso molecular:573.55Sorafenib
CAS:<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Forma y color:SolidPeso molecular:464.82Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Forma y color:SolidPeso molecular:426.85IMPDH2-IN-4
<p>IMPDH2-IN-4 (compound 2d) is a Mycophenolic acid analog and a selective IMPDH2 inhibitor with a Ki of 1.8 μM. It exhibits potent cytotoxic activity against osteosarcoma cancer cell lines. Additionally, IMPDH2-IN-4 demonstrates high affinity for VEGFR-2, CDK2, and IMPDH.</p>Fórmula:C35H34O6SiForma y color:SolidPeso molecular:578.73SU 4981
CAS:<p>SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.</p>Fórmula:C19H18N2O2Pureza:95.4%Forma y color:SoildPeso molecular:306.36VEGF-IN-1
<p>VEGF-IN-1 (compound 6) reduces the release of VEGF in U87-MG cells and inhibits angiogenesis in vitro. Additionally, it suppresses cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM against U87-MG cells.</p>Fórmula:C27H22Cl2N4RuForma y color:SolidPeso molecular:574.47Olinvacimab
CAS:<p>Olinvacimab (TTAC-0001) is a human monoclonal antibody targeting VEGFR-2/KDR with anti-angiogenic activity that blocks tumor angiogenesis.</p>Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Forma y color:LiquidSozinibercept
CAS:<p>Sozinibercept (OPT 302; VGX-300), a VEGFR-3 inhibitor, blocks VEGF-C/D to curb angiogenesis and vascular leakage, and treats rat diabetic retinal edema.</p>Forma y color:LiquidPulocimab
CAS:<p>Pulocimab, an anti-VEGFR2 monoclonal antibody (mAb), is utilized in cancer research [1].</p>Forma y color:LiquidAcrizanib
CAS:<p>Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.</p>Fórmula:C20H18F3N7O2Pureza:98.71% - 99.64%Forma y color:SolidPeso molecular:445.4VGX100
<p>VGX100 is a humanized antibody targeting VEGFC for the study of solid tumors.</p>Pureza:98.6% (SDS-PAGE); 99.1% (SEC-HPLC) - 98.6% (SDS-PAGE); 99.1% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.5kDaAntiproliferative agent-57
<p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>Forma y color:Odour SolidVulinacimab
CAS:<p>Vulinacimab (HLX-06) is a mAb targeting VEGFR-2, used in cancer research, vital for tumor angiogenesis and endothelial cell functions.</p>Forma y color:LiquidVEGFR-2-IN-55
<p>VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.</p>Forma y color:Odour Solid
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