PDGFR
Los inhibidores del receptor del factor de crecimiento derivado de plaquetas (PDGFR) son compuestos que bloquean la señalización del PDGFR, un receptor involucrado en el crecimiento celular, la proliferación y la angiogénesis. El PDGFR desempeña un papel significativo en el desarrollo de los vasos sanguíneos que abastecen a los tumores. Inhibir el PDGFR puede, por lo tanto, prevenir la angiogénesis, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de PDGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 126 productos de "PDGFR"
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Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:488.01GW 2580
CAS:Fórmula:C20H22N4O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:366.42TCS 359
CAS:Fórmula:C18H20N2O4SPureza:>98.0%(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:360.43Sorafenib Tosylate
CAS:Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:637.03Imatinib
CAS:Fórmula:C29H31N7OPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:493.62Imatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Forma y color:White Crystalline PowderPeso molecular:589.71Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Fórmula:C26H33FN4O7Pureza:98% - 99.26%Forma y color:SolidPeso molecular:532.564-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:Fórmula:C29H31N7OPureza:98%Forma y color:SolidPeso molecular:493.6027Ref: IN-DA00350H
1g25,00€5g33,00€10g56,00€1kg506,00€25g61,00€5kgA consultar100g164,00€10kgA consultar500g687,00€N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Fórmula:C28H29N7OPureza:98.60%Forma y color:Off-White To Pale-Yellow SolidPeso molecular:479.58Trapidil
CAS:<p>Trapidil (Avantrin) is a coronary vasodilator agent.</p>Fórmula:C10H15N5Pureza:99.42%Forma y color:SolidPeso molecular:205.262-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:95%Forma y color:SolidPeso molecular:360.42742-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
1g131,00€5g255,00€10g619,00€50g617,00€100gA consultar10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€Axitinib
CAS:<p>Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C22H18N4OSPureza:98.9% - 99.74%Forma y color:Off-White SolidPeso molecular:386.47Quinoxaline, 6,7-dimethoxy-2-phenyl-
CAS:Fórmula:C16H14N2O2Pureza:98%Forma y color:SolidPeso molecular:266.2946Ref: IN-DA001E48
1gA consultar1mg53,00€5mg54,00€10mg73,00€25mg107,00€50mg164,00€100mg187,00€250mg503,00€Pazopanib
CAS:<p>Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Forma y color:White PowderPeso molecular:437.52Olaratumab
CAS:<p>Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can be</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.70%Forma y color:LiquidPeso molecular:147.12 kDaJNJ-10198409
CAS:<p>JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.</p>Fórmula:C18H16FN3O2Pureza:98.51%Forma y color:SolidPeso molecular:325.34Sunitinib
CAS:<p>Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).</p>Fórmula:C22H27FN4O2Pureza:98% - 99.67%Forma y color:Yellow SolidPeso molecular:398.47Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Forma y color:SolidPeso molecular:426.85AG 1295
CAS:<p>AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.</p>Fórmula:C16H14N2Pureza:99.64%Forma y color:SolidPeso molecular:234.3Regorafénib N-oxyde (M2)
CAS:<p>Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.</p>Fórmula:C21H15ClF4N4O4Pureza:98.03% - 98.26%Forma y color:SolidPeso molecular:498.81KN1022
CAS:<p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>Fórmula:C21H22N6O5Pureza:99.68%Forma y color:SoildPeso molecular:438.44CT52923
CAS:<p>CT52923: selective oral PDGFR blocker, ATP-inhibitor, used in research for various diseases including cancer.</p>Fórmula:C23H25N5O4SPureza:99.926%Forma y color:SoildPeso molecular:467.54KIT/PDGFRA-IN-1
<p>KIT/PDGFRA-IN-1 (compound 19) is an inhibitor targeting the stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA). Its IC50 values are 2.3 µM for KIT-wt, 12 µM for KIT-D816H, 492 µM for KIT-T670I, 0.8 µM for PDGFRA-wt, 99.9 µM for PDGFRA-D842V, 42.3 µM for PDGFRA-T674I, and 4.3 µM for PDGFRA-G680R. The GR50 values for GIST-T1, T1-a-D842V, and GIST-48B cell lines (gastrointestinal stromal tumor cell lines with PDGFR and KIT mutations) are 12 nM, 8900 nM, and ≥10,000 nM, respectively.</p>Fórmula:C26H18F3N5O2Forma y color:SolidPeso molecular:489.449KG5
CAS:<p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>Fórmula:C20H16F3N7OSPureza:98.32%Forma y color:SolidPeso molecular:459.45IMC-2C5
<p>IMC-2C5 is a humanized monoclonal antibody targeting PDGFRB/CD140b.</p>Pureza:>95%Forma y color:Odour LiquidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Forma y color:Odour SolidRinucumab
CAS:<p>Rinucumab (REGN 2176) is an anti-PDGF IgG4-like monoclonal antibody that can be used to study age-related macular degeneration.</p>Pureza:99.2% (SDS-PAGE); 97.7% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidTrapidil
CAS:Fórmula:C10H15N5Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:205.27Tyrphostin A9
CAS:Fórmula:C18H22N2OPureza:>98.0%(GC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:282.39Regorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:482.82Anti-PDGFRB Antibody-APC (1A610)
<p>Anti-PDGFRB Antibody-APC (1A610) is a APC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (1A610) can be used in FCM.</p>Forma y color:Odour LiquidAnti-Phospho-PDGFRB (Tyr740) Antibody (9D509)
<p>Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) is an antibody targeting Phospho-PDGFRB (Tyr740). Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) can be used in ELISA, WB.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (7C914)
<p>Anti-PDGFRB Antibody (7C914) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (4V910)
<p>Anti-PDGFRB Antibody (4V910) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (4V910) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody-FITC (1A610)
<p>Anti-PDGFRB Antibody-FITC (1A610) is a FITC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (1A610) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (7W816)
<p>Anti-PDGFRB Antibody (7W816) is a Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody (7W816) can be used in ELISA(Cap).</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody-FITC (7C914)
<p>Anti-PDGFRB Antibody-FITC (7C914) is a FITC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (1A610)
<p>Anti-PDGFRB Antibody (1A610) is a Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody (1A610) can be used in ELISA,FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody-APC (7C914)
<p>Anti-PDGFRB Antibody-APC (7C914) is a APC-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (8J167)
<p>Anti-PDGFRB Antibody (8J167) is an antibody targeting PDGFRB. Anti-PDGFRB Antibody (8J167) can be used in ELISA, IHC.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody-PE (1A610)
<p>Anti-PDGFRB Antibody-PE (1A610) is a PE-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-PE (1A610) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody-PE (7C914)
<p>Anti-PDGFRB Antibody-PE (7C914) is a PE-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-PE (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (4H405)
<p>Anti-PDGFRB Antibody (4H405) is a Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody (4H405) can be used in ELISA(Det).</p>Forma y color:Odour LiquidTyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:589.72Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(T)(HPLC)Forma y color:White to Yellow to Yellow green powder to crystalPeso molecular:539.64Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:375.41AG-1296
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Orange to Green powder to crystalPeso molecular:266.30PDGF R β/CD140b Protein, Human, Recombinant (His & Avi)
<p>PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:59 kDa (predicted). Due to glycosylation, the protein migrates to 78-115 kDa based on Tris-Bis PAGE result.PDGFRB Protein, Human, Recombinant (His), Biotinylated
<p>PDGFRB Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:57.6 kDa (predicted)PDGF R β/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated
<p>PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:59 kDa (predicted). Due to glycosylation, the protein migrates to 78-115 kDa based on Tris-Bis PAGE result.PDGF R β/CD140b Protein, Canine, Recombinant (His)
<p>PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.</p>Forma y color:Lyophilized PowderPeso molecular:57.25 kDa (predicted). Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result.PDGFRB Protein, Human, Recombinant (His)
<p>PDGFRB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Forma y color:Lyophilized PowderPeso molecular:57.6 kDa (predicted); 95-100 kDa (reducing conditions)PDGFRB Protein, Human, Recombinant
<p>PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.</p>Forma y color:Lyophilized PowderPeso molecular:56.2 kDa (predicted)PDGFRB Protein, Human, Recombinant (hFc)
<p>PDGFRB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:82.8 kDa (predicted)PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51SU4312
CAS:<p>SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.</p>Fórmula:C17H16N2OPureza:>99.99%Forma y color:SolidPeso molecular:264.32PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Fórmula:C17H17N7Pureza:98.45% - 99.67%Forma y color:SolidPeso molecular:319.36Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Forma y color:SolidPeso molecular:594.75TAK-593
CAS:<p>TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively).</p>Fórmula:C23H23N7O3Pureza:99.37%Forma y color:SolidPeso molecular:445.47Seralutinib
CAS:<p>Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.</p>Fórmula:C27H27N5O3Pureza:99.09%Forma y color:SolidPeso molecular:469.54Amuvatinib
CAS:<p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>Fórmula:C23H21N5O3SPureza:99.38% - >99.99%Forma y color:SolidPeso molecular:447.51PD-089828
CAS:<p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>Fórmula:C18H18Cl2N6OPureza:97.39%Forma y color:SolidPeso molecular:405.28Crenolanib
CAS:<p>Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).</p>Fórmula:C26H29N5O2Pureza:98.40% - 99.73%Forma y color:SolidPeso molecular:443.54Vorolanib
CAS:<p>Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.</p>Fórmula:C23H26FN5O3Pureza:97.35%Forma y color:SolidPeso molecular:439.48Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Fórmula:C28H30N6OSPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:498.64Avapritinib
CAS:<p>Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.</p>Fórmula:C26H27FN10Pureza:96.59% - 99.7%Forma y color:SolidPeso molecular:498.56Nintedanib esylate
CAS:<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>Fórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.96%Forma y color:SolidPeso molecular:649.76Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45Flumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Forma y color:SolidPeso molecular:562.59Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Fórmula:C18H22N2OPureza:98.21% - 99.87%Forma y color:Yellow SolidPeso molecular:282.38N-(p-Coumaroyl) serotonin
CAS:<p>N-(p-Coumaroyl) Serotonin, from safflower seeds, has antioxidant, antitumor properties and improves vascular health.</p>Fórmula:C19H18N2O3Pureza:98.10% - 98.89%Forma y color:SolidPeso molecular:322.36SU 5402
CAS:<p>SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.</p>Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Forma y color:Yellow-Green SolidPeso molecular:296.32AZD2932
CAS:<p>AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.</p>Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Forma y color:SolidPeso molecular:447.49Sennoside B
CAS:<p>Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.</p>Fórmula:C42H38O20Pureza:92.85% - 98.92%Forma y color:Light Yellow CrystalPeso molecular:862.74Dovitinib lactate hydrate
CAS:<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Fórmula:C24H27FN6O4Pureza:99.82%Forma y color:SolidPeso molecular:482.51Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Forma y color:SolidPeso molecular:482.51Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Forma y color:SolidPeso molecular:450.51Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Forma y color:White SolidPeso molecular:562.7ON123300
CAS:<p>ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).</p>Fórmula:C24H27N7OPureza:99.22% - 99.53%Forma y color:SolidPeso molecular:429.52Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Forma y color:SolidPeso molecular:310.35Tyrphostin AG1296
CAS:<p>Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.</p>Fórmula:C16H14N2O2Pureza:99.94% - >99.99%Forma y color:SolidPeso molecular:266.29SU4984
CAS:<p>SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).</p>Fórmula:C20H19N3O2Pureza:97.20%Forma y color:SolidPeso molecular:333.38JI-101
CAS:<p>JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.</p>Fórmula:C22H20BrN5O2Pureza:99.41% - 99.97%Forma y color:SolidPeso molecular:466.33Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Forma y color:SolidPeso molecular:488.54Imatinib
CAS:<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Fórmula:C29H31N7OPureza:99.42% - 99.94%Forma y color:Off White PowderPeso molecular:493.6Telatinib
CAS:<p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Forma y color:SolidPeso molecular:409.83Methylnissolin
CAS:<p>Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.</p>Fórmula:C17H16O5Pureza:99.68% - 99.98%Forma y color:SolidPeso molecular:300.31Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Forma y color:SolidPeso molecular:500.83Lenvatinib mesylate
CAS:<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Forma y color:SolidPeso molecular:522.96Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Fórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:SolidPeso molecular:375.4PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22GW786034B
CAS:<p>Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.</p>Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98CHIR-124
CAS:<p>CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.</p>Fórmula:C23H22ClN5OPureza:96.33% - 98.35%Forma y color:SolidPeso molecular:419.91Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56Regorafenib
CAS:<p>Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally</p>Fórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Forma y color:SolidPeso molecular:482.82Ripretinib
CAS:<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.38%Forma y color:SolidPeso molecular:510.36XL 999
CAS:<p>Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）</p>Fórmula:C26H28FN5OPureza:98.24% - 99.55%Forma y color:SolidPeso molecular:445.53Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Fórmula:C21H16Cl2F4N4O3Pureza:99.56%Forma y color:SolidPeso molecular:519.28Flumatinib mesylate
CAS:<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Fórmula:C30H33F3N8O4SPureza:99.82%Forma y color:SolidPeso molecular:658.69Nintedanib
CAS:<p>Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/</p>Fórmula:C31H33N5O4Pureza:98% - 99.92%Forma y color:SolidPeso molecular:539.62SU14813
CAS:<p>SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.</p>Fórmula:C23H27FN4O4Pureza:98.13%Forma y color:SolidPeso molecular:442.48CP-673451
CAS:<p>CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other</p>Fórmula:C24H27N5O2Pureza:99.62% - 99.88%Forma y color:SolidPeso molecular:417.5NVP-ACC789
CAS:<p>ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.</p>Fórmula:C21H17BrN4Pureza:99.44% - 99.63%Forma y color:SolidPeso molecular:405.29Dovitinib
CAS:<p>Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.</p>Fórmula:C21H21FN6OPureza:99.35% - 99.92%Forma y color:SolidPeso molecular:392.43ENMD-2076
CAS:<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Fórmula:C21H25N7Pureza:97.63% - ≥95%Forma y color:SolidPeso molecular:375.47PDGFR Tyrosine Kinase Inhibitor III
CAS:<p>PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that</p>Fórmula:C27H27N5O4Pureza:99.50%Forma y color:SoildPeso molecular:485.53Toceranib
CAS:<p>Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.</p>Fórmula:C22H25FN4O2Pureza:97.14%Forma y color:SolidPeso molecular:396.46Tovetumab
CAS:<p>Tovetumab (MEDI-575) is an anti-PDGFRα mAb inhibiting its signaling, in trials for glioblastoma and NSCLC.</p>Pureza:95%Forma y color:LiquidE-4177
CAS:<p>E-4177 is an angiotensin II type 1 receptor (AT1R) antagonist and can be used to study cardiovascular diseases.</p>Fórmula:C24H21N3O2Pureza:98.67% - 99.57%Forma y color:SolidPeso molecular:383.44DMPQ dihydrochloride
CAS:<p>PDGFRβ inhibitor</p>Fórmula:C16H16Cl2N2O2Pureza:99.51%Forma y color:SolidPeso molecular:339.22AC710 Mesylate
CAS:<p>AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ).</p>Fórmula:C32H46N6O7SPureza:98%Forma y color:SolidPeso molecular:658.81AC710
CAS:<p>AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).</p>Fórmula:C31H42N6O4Pureza:99.67%Forma y color:SolidPeso molecular:562.7PDGFRα kinase inhibitor 1
CAS:<p>PDGFRα kinase inhibitor 1 is a type II PDGFRα kinase inhibitor that inhibits both PDGFRα and PDGFRβ.</p>Fórmula:C34H34N8O2Pureza:99.78%Forma y color:SolidPeso molecular:586.69Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47SU16f
CAS:<p>SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.</p>Fórmula:C24H22N2O3Pureza:97.69%Forma y color:SolidPeso molecular:386.44BMS-605541
CAS:<p>BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).</p>Fórmula:C19H17F2N5OSPureza:98.07%Forma y color:SolidPeso molecular:401.43TG 100572 Hydrochloride
CAS:<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Fórmula:C26H27Cl2N5O2Pureza:98%Forma y color:SolidPeso molecular:512.43Tyrphostin AG1433
CAS:<p>Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).</p>Fórmula:C16H14N2O2Pureza:98.47%Forma y color:SolidPeso molecular:266.292-Methyl-3-phenylquinoxaline
CAS:<p>2-Methyl-3-phenylquinoxaline (compound 38) serves as an effective inhibitor of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK), exhibiting significant inhibitory activity against the full-length PDGFR kinase in intact cells (IC50 greater than 100 μM).</p>Fórmula:C15H12N2Forma y color:SolidPeso molecular:220.27
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