PDGFR
Los inhibidores del receptor del factor de crecimiento derivado de plaquetas (PDGFR) son compuestos que bloquean la señalización del PDGFR, un receptor involucrado en el crecimiento celular, la proliferación y la angiogénesis. El PDGFR desempeña un papel significativo en el desarrollo de los vasos sanguíneos que abastecen a los tumores. Inhibir el PDGFR puede, por lo tanto, prevenir la angiogénesis, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de PDGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 126 productos de "PDGFR"
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Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Forma y color:SolidPeso molecular:426.852-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:95%Forma y color:SolidPeso molecular:360.4274Trapidil
CAS:<p>Trapidil (Avantrin) is a coronary vasodilator agent.</p>Fórmula:C10H15N5Pureza:99.42%Forma y color:SolidPeso molecular:205.26CT52923
CAS:<p>CT52923: selective oral PDGFR blocker, ATP-inhibitor, used in research for various diseases including cancer.</p>Fórmula:C23H25N5O4SPureza:99.926%Forma y color:SoildPeso molecular:467.54KG5
CAS:<p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>Fórmula:C20H16F3N7OSPureza:98.32%Forma y color:SolidPeso molecular:459.45IMC-2C5
<p>IMC-2C5 is a humanized monoclonal antibody targeting PDGFRB/CD140b.</p>Pureza:>95%Forma y color:Odour LiquidKN1022
CAS:<p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>Fórmula:C21H22N6O5Pureza:99.68%Forma y color:SoildPeso molecular:438.44Rinucumab
CAS:<p>Rinucumab (REGN 2176) is an anti-PDGF IgG4-like monoclonal antibody that can be used to study age-related macular degeneration.</p>Pureza:99.2% (SDS-PAGE); 97.7% (SEC-HPLC) - 99.2% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Forma y color:Odour SolidKIT/PDGFRA-IN-1
<p>KIT/PDGFRA-IN-1 (compound 19) is an inhibitor targeting the stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA). Its IC50 values are 2.3 µM for KIT-wt, 12 µM for KIT-D816H, 492 µM for KIT-T670I, 0.8 µM for PDGFRA-wt, 99.9 µM for PDGFRA-D842V, 42.3 µM for PDGFRA-T674I, and 4.3 µM for PDGFRA-G680R. The GR50 values for GIST-T1, T1-a-D842V, and GIST-48B cell lines (gastrointestinal stromal tumor cell lines with PDGFR and KIT mutations) are 12 nM, 8900 nM, and ≥10,000 nM, respectively.</p>Fórmula:C26H18F3N5O2Forma y color:SolidPeso molecular:489.449Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-PDGFRB Antibody (4H405)
<p>Anti-PDGFRB Antibody (4H405) is a Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody (4H405) can be used in ELISA(Det).</p>Forma y color:Odour LiquidRegorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:482.82Anti-PDGFRB Antibody-FITC (1A610)
<p>Anti-PDGFRB Antibody-FITC (1A610) is a FITC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-FITC (1A610) can be used in FCM.</p>Forma y color:Odour LiquidTyrphostin A9
CAS:Fórmula:C18H22N2OPureza:>98.0%(GC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:282.39Anti-PDGFRB Antibody-PE (7C914)
<p>Anti-PDGFRB Antibody-PE (7C914) is a PE-conjugated Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody-PE (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (4V910)
<p>Anti-PDGFRB Antibody (4V910) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (4V910) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-PDGFRB Antibody (7C914)
<p>Anti-PDGFRB Antibody (7C914) is a Rabbit antibody targeting PDGFRB. Anti-PDGFRB Antibody (7C914) can be used in FCM.</p>Forma y color:Odour LiquidAnti-Phospho-PDGFRB (Tyr740) Antibody (9D509)
<p>Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) is an antibody targeting Phospho-PDGFRB (Tyr740). Anti-Phospho-PDGFRB (Tyr740) Antibody (9D509) can be used in ELISA, WB.</p>Forma y color:Odour Liquid
