PDGFR
Los inhibidores del receptor del factor de crecimiento derivado de plaquetas (PDGFR) son compuestos que bloquean la señalización del PDGFR, un receptor involucrado en el crecimiento celular, la proliferación y la angiogénesis. El PDGFR desempeña un papel significativo en el desarrollo de los vasos sanguíneos que abastecen a los tumores. Inhibir el PDGFR puede, por lo tanto, prevenir la angiogénesis, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de PDGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 127 productos de "PDGFR"
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N-(p-Coumaroyl) serotonin
CAS:N-(p-Coumaroyl) Serotonin, from safflower seeds, has antioxidant, antitumor properties and improves vascular health.Fórmula:C19H18N2O3Pureza:98.10% - 98.89%Forma y color:SolidPeso molecular:322.36SU4312
CAS:SU-4312 (DMBI) inhibits VEGFR & PDGFR (IC50: 0.8, 19.4 μM) and shields neurons from MPP(+)-induced damage by blocking nNOS.
Fórmula:C17H16N2OPureza:>99.99%Forma y color:SolidPeso molecular:264.32Seralutinib
CAS:Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Fórmula:C27H27N5O3Pureza:99.09%Forma y color:SolidPeso molecular:469.54Ref: TM-T8900
1mg47,00€2mg62,00€5mg92,00€10mg137,00€25mg236,00€50mg313,00€100mg497,00€1mL*10mM (DMSO)92,00€PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:98.45% - 99.93%Forma y color:SolidPeso molecular:319.36PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Fórmula:C18H18Cl2N6OPureza:97.39%Forma y color:SolidPeso molecular:405.28Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Forma y color:SolidPeso molecular:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Fórmula:C23H26FN5O3Pureza:97.35%Forma y color:SolidPeso molecular:439.48Ref: TM-T8491
1mg101,00€2mg142,00€5mg215,00€10mg340,00€25mg583,00€50mg842,00€100mg1.144,00€200mg1.521,00€1mL*10mM (DMSO)236,00€CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFórmula:C24H27N5O2Pureza:99.62% - 99.88%Forma y color:SolidPeso molecular:417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€1mL*10mM (DMSO)108,00€Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:498.64Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Fórmula:C26H27FN10Pureza:96.59% - 99.7%Forma y color:SolidPeso molecular:498.56Ref: TM-T5109
1mg38,00€5mg80,00€10mg120,00€25mg235,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)175,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.98%Forma y color:SolidPeso molecular:649.76Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€1mL*10mM (DMSO)87,00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:98.13%Forma y color:SolidPeso molecular:442.48Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Forma y color:SolidPeso molecular:562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€1mL*10mM (DMSO)82,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Forma y color:Yellow SolidPeso molecular:282.38SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Forma y color:Yellow-Green SolidPeso molecular:296.32PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51Ref: TM-T23127
1mg34,00€5mg96,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€1mL*10mM (DMSO)118,00€Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45Sennoside B
CAS:Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.Fórmula:C42H38O20Pureza:92.85% - 98.92%Forma y color:Light Yellow CrystalPeso molecular:862.74
