FLT
Los inhibidores de la FLT (quinasa de tirosina similar a Fms) son compuestos que se dirigen a los receptores FLT, los cuales están involucrados en la regulación de la angiogénesis a través de la vía del VEGF (factor de crecimiento endotelial vascular). Los receptores FLT desempeñan un papel crucial en el desarrollo de nuevos vasos sanguíneos en los tumores. Inhibir los receptores FLT puede reducir eficazmente la angiogénesis y el crecimiento tumoral, lo que hace que estos inhibidores sean importantes en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de FLT de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Se han encontrado 86 productos de "FLT"
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FLT3-IN-22
FLT3-IN-22 (compound 22f) is a potent inhibitor of FLT3, demonstrating IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant.Fórmula:C24H22N6O2Forma y color:SolidPeso molecular:426.47FLT3-IN-10
CAS:FLT3-IN-10, a potent FLT3 inhibitor, may treat FLT3-mutated AML.Fórmula:C15H11FN2OPureza:99.8%Forma y color:SolidPeso molecular:254.26Ref: TM-T9856
2mg35,00€1mL*10mM (DMSO)54,00€5mg56,00€10mg96,00€25mg172,00€50mg254,00€100mg360,00€200mg490,00€FLT3-IN-16
CAS:FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Fórmula:C15H15N3O2SPureza:99.21%Forma y color:SolidPeso molecular:301.36Ref: TM-T9843
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg172,00€50mg260,00€100mg369,00€200mg487,00€FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-02108
5µg65,00€10µg94,00€20µg153,00€50µg291,00€100µg554,00€200µg827,00€500µg1.598,00€1mg3.278,00€FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Forma y color:Lyophilized PowderPeso molecular:85.45 kDa (predicted); 113.32 kDa (reducing conditions)Anti-FLT1 Antibody (6K171)
Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.Forma y color:Odour LiquidAnti-FLT1 Antibody (3W705)
Anti-FLT1 Antibody (3W705) is an antibody targeting FLT1. Anti-FLT1 Antibody (3W705) can be used in ELISA, WB, IHC, FCM.Forma y color:Odour LiquidFLT1 Protein, Human, Recombinant (hFc)
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:61.1 kDa (predicted)Ref: TM-TMPY-00119
5µg85,00€10µg119,00€20µg192,00€50µg388,00€100µg655,00€200µg1.151,00€500µg2.777,00€Anti-FLT1 Antibody (6S618)
Anti-FLT1 Antibody (6S618) is an antibody targeting FLT1. Anti-FLT1 Antibody (6S618) can be used in ELISA, IHC.Forma y color:Odour LiquidAnti-VEGFR1/FLT-1 Antibody (9F18)
Anti-VEGFR1/FLT-1 Antibody (9F18) is a Rabbit antibody targeting VEGFR1/FLT-1. Anti-VEGFR1/FLT-1 Antibody (9F18) can be used in ELISA.Forma y color:Odour LiquidFLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.Pureza:97.5%Forma y color:Lyophilized PowderPeso molecular:35.6 kDa (predicted)BPR1K871
CAS:BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFórmula:C25H28ClN7O2SForma y color:SolidPeso molecular:526.05VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00451
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.BPR1J-097 hydrochloride (1327167-19-0(free base))
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
Fórmula:C27H29ClN6O3SPureza:98% - 98.54%Forma y color:SolidPeso molecular:553.07TCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Fórmula:C18H20N2O4SPureza:99.31%Forma y color:SolidPeso molecular:360.43Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Fórmula:C28H32N4O3Pureza:99.25% - 99.49%Forma y color:SolidPeso molecular:472.58UNC2025
CAS:UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor.Fórmula:C28H40N6OPureza:99.53% - 99.74%Forma y color:SolidPeso molecular:476.66INE963
CAS:INE963: Potent against Pf 3D7 (EC50=6nM), clears parasites in <24h; effective on P. falciparum/vivax isolates (EC50=0.01-7nM).Fórmula:C19H26N6O2SPureza:99.08% - 99.45%Forma y color:SolidPeso molecular:402.51FLT3-IN-2
CAS:FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Fórmula:C21H16ClF3N4Pureza:97.57% - 98.53%Forma y color:SolidPeso molecular:416.83Ref: TM-T1938
1mg40,00€2mg52,00€5mg82,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€
