c-Kit
Los inhibidores de c-Kit son compuestos que bloquean la actividad del Receptor del Factor de Células Madre (c-Kit), una tirosina quinasa que desempeña un papel crucial en la supervivencia, proliferación y diferenciación celular, particularmente en células hematopoyéticas. Las mutaciones en c-Kit están vinculadas a varios tipos de cáncer, incluidos los tumores del estroma gastrointestinal (GIST) y la leucemia. En CymitQuimica, ofrecemos inhibidores de c-Kit para apoyar su investigación en oncología, hematología y biología de células madre.
Se han encontrado 101 productos de "c-Kit"
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N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Fórmula:C28H29N7OPureza:98.60%Forma y color:Off-White To Pale-Yellow SolidPeso molecular:479.58Imatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Forma y color:White Crystalline PowderPeso molecular:589.71Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Forma y color:SolidPeso molecular:426.85Pazopanib
CAS:<p>Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Forma y color:White PowderPeso molecular:437.52JI6
CAS:<p>JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.</p>Fórmula:C19H17N3O4SPureza:98.51%Forma y color:SoildPeso molecular:383.42Amuvatinib hydrochloride
CAS:<p>Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.</p>Fórmula:C23H22ClN5O3SPureza:98%Forma y color:SolidPeso molecular:483.97M4205
CAS:<p>M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.</p>Fórmula:C29H32N8OPureza:99.07%Forma y color:SolidPeso molecular:508.62KG5
CAS:<p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>Fórmula:C20H16F3N7OSPureza:98.32%Forma y color:SolidPeso molecular:459.45Motesanib Diphosphate
CAS:<p>Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic</p>Fórmula:C22H23N5O·2H3PO4Pureza:99.69%Forma y color:SolidPeso molecular:569.44Multi-kinase-IN-5
<p>Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,</p>Fórmula:C19H15N5O2SForma y color:SolidPeso molecular:377.42c-Kit-IN-6
<p>C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.</p>Fórmula:C25H28FN5O5Forma y color:SolidPeso molecular:497.52Anti-C-Kit Antibody-PE (7P530)
<p>Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (1R766)
<p>Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (7P530)
<p>Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
<p>Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
<p>Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-APC (1R766)
<p>Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (8E724)
<p>Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-FITC (7P530)
<p>Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-CD117 Antibody (9H202)
<p>Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.</p>Forma y color:Odour Liquid
