c-Kit
Los inhibidores de c-Kit son compuestos que bloquean la actividad del Receptor del Factor de Células Madre (c-Kit), una tirosina quinasa que desempeña un papel crucial en la supervivencia, proliferación y diferenciación celular, particularmente en células hematopoyéticas. Las mutaciones en c-Kit están vinculadas a varios tipos de cáncer, incluidos los tumores del estroma gastrointestinal (GIST) y la leucemia. En CymitQuimica, ofrecemos inhibidores de c-Kit para apoyar su investigación en oncología, hematología y biología de células madre.
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N-Desmethyl imatinib
CAS:404844-02-6
N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target …
Fórmula:
C28H29N7O
Pureza:
98.60%
Forma y color:
Off-White To Pale-Yellow Solid
Peso molecular:
479.58
Ref: TM-T11641
| 1mg | 92,00 € | ||
| 5mg | 170,00 € | ||
| 10mg | 319,00 € | ||
| 25mg | 540,00 € | ||
| 50mg | 777,00 € | ||
| 100mg | 1.074,00 € | ||
| 1mL*10mM (DMSO) | 178,00 € |
Entrega estimada en Estados Unidos, el Miércoles 9 de Abril de 2025
Lenvatinib
CAS:417716-92-8
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, …
Fórmula:
C21H19ClN4O4
Pureza:
98.46% - 99.8000%
Forma y color:
Solid
Peso molecular:
426.85
Ref: TM-T0520
| 5mg | 48,00 € | ||
| 10mg | 62,00 € | ||
| 25mg | 95,00 € | ||
| 50mg | 120,00 € | ||
| 100mg | 177,00 € | ||
| 500mg | 439,00 € |
Entrega estimada en Estados Unidos, el Miércoles 9 de Abril de 2025
Imatinib Mesylate
CAS:220127-57-1
Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, …
Fórmula:
C29H31N7O·CH4SO3
Pureza:
100% - 99.97%
Forma y color:
White Crystalline Powder
Peso molecular:
589.71
Ref: TM-T1621
| 1u | 163,20 € | ||
| 200mg | 59,00 € | ||
| 500mg | 89,00 € | ||
| 1mL*10mM (DMSO) | 55,00 € |
Entrega estimada en Estados Unidos, el Miércoles 9 de Abril de 2025
Pazopanib
CAS:444731-52-6
Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor …
Fórmula:
C21H23N7O2S
Pureza:
98.78% - 99.72%
Forma y color:
White Powder
Peso molecular:
437.52
Ref: TM-T0097L
| 10mg | 49,00 € | ||
| 25mg | 73,00 € | ||
| 50mg | 96,00 € | ||
| 100mg | 145,00 € | ||
| 200mg | 236,00 € | ||
| 500mg | 331,00 € | ||
| 1mL*10mM (DMSO) | 59,00 € |
Entrega estimada en Estados Unidos, el Miércoles 9 de Abril de 2025
Motesanib Diphosphate
CAS:857876-30-3
Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase …
Fórmula:
C22H23N5O·2H3PO4
Pureza:
99.76%
Forma y color:
Solid
Peso molecular:
569.44
Ref: TM-T2288L
| 5mg | 43,00 € | ||
| 10mg | 57,00 € | ||
| 25mg | 96,00 € | ||
| 50mg | 168,00 € | ||
| 100mg | 283,00 € | ||
| 500mg | 692,00 € | ||
| 1mL*10mM (DMSO) | 59,00 € |
Entrega estimada en Estados Unidos, el Jueves 10 de Abril de 2025
KG5
CAS:877874-85-6
KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM …
Fórmula:
C20H16F3N7OS
Pureza:
98.2%
Forma y color:
Liquid
Peso molecular:
459.45
Ref: TM-T41003
| 1mg | 34,00 € | ||
| 2mg | 47,00 € | ||
| 5mg | 74,00 € | ||
| 10mg | 105,00 € | ||
| 25mg | 205,00 € | ||
| 50mg | 313,00 € | ||
| 100mg | 449,00 € | ||
| 200mg | 628,00 € | ||
| 1mL*10mM (DMSO) | 89,00 € |
Entrega estimada en Estados Unidos, el Jueves 10 de Abril de 2025
c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM …
Fórmula:
C25H28FN5O5
Forma y color:
Liquid
Peso molecular:
497.52
Ref: TM-T200940
| 10mg | A consultar | ||
| 50mg | A consultar |
Entrega estimada en Estados Unidos, el Jueves 10 de Abril de 2025
M4205
CAS:2590556-80-0
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, …
Fórmula:
C29H32N8O
Pureza:
98.52%
Forma y color:
Liquid
Peso molecular:
508.62
Ref: TM-T9689
| 1mg | 52,00 € | ||
| 5mg | 116,00 € | ||
| 10mg | 178,00 € | ||
| 25mg | 306,00 € | ||
| 50mg | 437,00 € | ||
| 100mg | 605,00 € | ||
| 200mg | 815,00 € | ||
| 1mL*10mM (DMSO) | 129,00 € |
Entrega estimada en Estados Unidos, el Jueves 10 de Abril de 2025
CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types …
Forma y color:
Liquid
Peso molecular:
58.60 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00805
| 1mg | 5.169,00 € | ||
| 100µg | 773,00 € | ||
| 500µg | 3.087,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
Toceranib
CAS:356068-94-5
Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM …
Fórmula:
C22H25FN4O2
Pureza:
97.14%
Forma y color:
Solid
Peso molecular:
396.46
Ref: TM-T13178
| 10mg | 47,00 € | ||
| 25mg | 65,00 € | ||
| 50mg | 88,00 € | ||
| 100mg | 116,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells …
Forma y color:
Liquid
Peso molecular:
76.8 kDa (predicted); 68 kDa (reducing conditions)
Ref: TM-TMPY-04564
| 50µg | 379,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Pureza:
99.4%
Forma y color:
Liquid
Peso molecular:
56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01935
| 100µg | 366,00 € | ||
| 200µg | 647,00 € | ||
| 500µg | 1.369,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Forma y color:
Liquid
Peso molecular:
82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01801
| 100µg | 570,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.
Pureza:
98.2%
Forma y color:
Liquid
Peso molecular:
57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)
Ref: TM-TMPY-01802
| 100µg | 366,00 € | ||
| 200µg | 647,00 € | ||
| 500µg | 1.369,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.
Forma y color:
Liquid
Peso molecular:
17.9 kDa (predicted); 18 kDa (reducing conditions)
Ref: TM-TMPY-03567
| 100µg | 665,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with …
Forma y color:
Liquid
Peso molecular:
58.50 kDa (predicted); 87.1 kDa (reducing conditions)
Ref: TM-TMPY-06656
| 20µg | 570,00 € | ||
| 100µg | 1.320,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including …
Forma y color:
Liquid
Peso molecular:
56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-01270
| 1mg | 3.087,00 € | ||
| 100µg | 462,00 € | ||
| 500µg | 1.853,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
PLX647
CAS:873786-09-5
PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).
Fórmula:
C21H17F3N4
Pureza:
99.38%
Forma y color:
Solid
Peso molecular:
382.38
Ref: TM-T1925
| 1mg | 35,00 € | ||
| 5mg | 65,00 € | ||
| 10mg | 90,00 € | ||
| 25mg | 134,00 € | ||
| 50mg | 188,00 € | ||
| 100mg | 279,00 € | ||
| 200mg | 411,00 € | ||
| 1mL*10mM (DMSO) | 64,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types …
Forma y color:
Liquid
Peso molecular:
56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.
Ref: TM-TMPK-00777
| 1mg | 3.087,00 € | ||
| 100µg | 462,00 € | ||
| 500µg | 1.853,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
c-Kit Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.
Pureza:
97.1%
Forma y color:
Liquid
Peso molecular:
82 kDa (predicted); 93-115 kDa (reducing conditions)
Ref: TM-TMPY-04051
| 50µg | 243,00 € | ||
| 100µg | 414,00 € | ||
| 200µg | 703,00 € | ||
| 500µg | 1.415,00 € |
Entrega estimada en Estados Unidos, el Lunes 14 de Abril de 2025
