c-Kit
Los inhibidores de c-Kit son compuestos que bloquean la actividad del Receptor del Factor de Células Madre (c-Kit), una tirosina quinasa que desempeña un papel crucial en la supervivencia, proliferación y diferenciación celular, particularmente en células hematopoyéticas. Las mutaciones en c-Kit están vinculadas a varios tipos de cáncer, incluidos los tumores del estroma gastrointestinal (GIST) y la leucemia. En CymitQuimica, ofrecemos inhibidores de c-Kit para apoyar su investigación en oncología, hematología y biología de células madre.
Se han encontrado 101 productos de "c-Kit"
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Imatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Forma y color:White Crystalline PowderPeso molecular:589.71N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Fórmula:C28H29N7OPureza:98.60%Forma y color:Off-White To Pale-Yellow SolidPeso molecular:479.58JI6
CAS:<p>JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.</p>Fórmula:C19H17N3O4SPureza:98.51%Forma y color:SoildPeso molecular:383.42Pazopanib
CAS:<p>Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Forma y color:White PowderPeso molecular:437.52Lenvatinib
CAS:<p>Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.</p>Fórmula:C21H19ClN4O4Pureza:98.46% - 99.69%Forma y color:SolidPeso molecular:426.85Multi-kinase-IN-5
<p>Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,</p>Fórmula:C19H15N5O2SForma y color:SolidPeso molecular:377.42c-Kit-IN-6
<p>C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.</p>Fórmula:C25H28FN5O5Forma y color:SolidPeso molecular:497.52Motesanib Diphosphate
CAS:<p>Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplastic</p>Fórmula:C22H23N5O·2H3PO4Pureza:99.69%Forma y color:SolidPeso molecular:569.44KG5
CAS:<p>KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).</p>Fórmula:C20H16F3N7OSPureza:98.32%Forma y color:SolidPeso molecular:459.45M4205
CAS:<p>M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.</p>Fórmula:C29H32N8OPureza:99.07%Forma y color:SolidPeso molecular:508.62Amuvatinib hydrochloride
CAS:<p>Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.</p>Fórmula:C23H22ClN5O3SPureza:98%Forma y color:SolidPeso molecular:483.97Anti-C-Kit Antibody (9Y519)
<p>Anti-C-Kit Antibody (9Y519) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (9Y519) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (2T761)
<p>Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).</p>Forma y color:Odour Liquidc-Kit/CD117 Protein, Human, Recombinant (aa 540-972, His & GST)
<p>c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag.</p>Forma y color:Lyophilized PowderPeso molecular:76.8 kDa (predicted); 68 kDa (reducing conditions)Anti-C-Kit Antibody-PE (1R766)
<p>Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (6X205)
<p>Anti-C-Kit Antibody (6X205) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (6X205) can be used in ELISA.</p>Forma y color:Odour Liquidc-Kit/CD117 Protein, Human, Recombinant (aa 50-190, His)
<p>c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:17.9 kDa (predicted); 18 kDa (reducing conditions)Anti-C-Kit Antibody (3N57)
<p>Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).</p>Forma y color:Odour Liquidc-Kit/CD117 Protein, Mouse, Recombinant (His)
<p>The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.</p>Forma y color:Lyophilized PowderPeso molecular:56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Mouse, Recombinant (hFc)
<p>c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Forma y color:Lyophilized PowderPeso molecular:82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Human, Recombinant (His)
<p>c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:99.4%Forma y color:Lyophilized PowderPeso molecular:56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Mouse, Recombinant (His)
<p>c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.2%Forma y color:Lyophilized PowderPeso molecular:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)Telatinib mesylate
CAS:<p>Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).</p>Fórmula:C21H20ClN5O6SForma y color:SolidPeso molecular:505.93c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.</p>Forma y color:Lyophilized PowderPeso molecular:56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Human, Recombinant (hFc)
<p>c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Pureza:97.1%Forma y color:Lyophilized PowderPeso molecular:82 kDa (predicted); 93-115 kDa (reducing conditions)Anti-C-Kit Antibody-APC (8E724)
<p>Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (7P530)
<p>Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
<p>Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-FITC (7P530)
<p>Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-CD117 Antibody (9H202)
<p>Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (1R766)
<p>Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
<p>Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (3F840)
<p>Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-PE (8E724)
<p>Anti-C-Kit Antibody-PE (8E724) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (8E724) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody (8E724)
<p>Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.</p>Forma y color:Odour LiquidPLX647
CAS:<p>PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).</p>Fórmula:C21H17F3N4Pureza:99.38%Forma y color:SolidPeso molecular:382.38Anti-C-Kit Antibody (3B930)
<p>Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-PE (7P530)
<p>Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.</p>Forma y color:Odour LiquidAnti-C-Kit Antibody-APC (1R766)
<p>Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.</p>Forma y color:Odour LiquidFlumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Forma y color:SolidPeso molecular:562.59BLU-263
CAS:<p>BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.</p>Fórmula:C27H29FN10OPureza:99.01% - 99.67%Forma y color:SolidPeso molecular:528.58Ki20227
CAS:<p>Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).</p>Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54Toceranib Phosphate
CAS:<p>Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.</p>Fórmula:C22H28FN4O6PPureza:98.56%Forma y color:SolidPeso molecular:494.45Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37JNJ-38158471
CAS:<p>JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .</p>Fórmula:C15H17ClN6O3Pureza:97.08%Forma y color:SolidPeso molecular:364.79Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Forma y color:White SolidPeso molecular:562.7Telatinib
CAS:<p>Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.</p>Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Forma y color:SolidPeso molecular:409.83Dovitinib lactate
CAS:<p>Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).</p>Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Forma y color:SolidPeso molecular:482.51Midostaurin
CAS:<p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Forma y color:SolidPeso molecular:570.64Avapritinib
CAS:<p>Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.</p>Fórmula:C26H27FN10Pureza:96.59% - 99.7%Forma y color:SolidPeso molecular:498.56
