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Autofagia

Autofagia

Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.

Se han encontrado 1424 productos de "Autofagia"

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  • KAN0438757

    CAS:
    <p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>
    Fórmula:C21H18FNO7S
    Pureza:99.34%
    Forma y color:Solid
    Peso molecular:447.43
  • Pravastatin sodium

    CAS:
    <p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>
    Fórmula:C23H35NaO7
    Pureza:97.14%
    Forma y color:White Crystalline Powder
    Peso molecular:446.52
  • Raloxifene hydrochloride

    CAS:
    <p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>
    Fórmula:C28H28ClNO4S
    Pureza:98% - 99.97%
    Forma y color:Light Yellow Solid
    Peso molecular:510.044
  • LY2183240

    CAS:
    <p>LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM).</p>
    Fórmula:C17H17N5O
    Pureza:99.26%
    Forma y color:Solid
    Peso molecular:307.35
  • Ivermectin

    CAS:
    <p>Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.</p>
    Fórmula:C48H74O14
    Pureza:94.11% - 99.71%
    Forma y color:Solid
    Peso molecular:875.09
  • Clemastine fumarate

    CAS:
    <p>Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.</p>
    Fórmula:C25H30ClNO5
    Pureza:99.52% - >99.99%
    Forma y color:Colorless To Faintly Yellow Crystalline Powder Appearance White Or Almost White Crystalline Powder
    Peso molecular:459.97
  • Naringin

    CAS:
    <p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>
    Fórmula:C27H32O14
    Pureza:99.23%
    Forma y color:Beige Creamish Powder Solid Solid Particulate/Powder
    Peso molecular:580.53
  • Sorafenib

    CAS:
    <p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>
    Fórmula:C21H16ClF3N4O3
    Pureza:98% - 99.89%
    Forma y color:Solid
    Peso molecular:464.82
  • Aumitin

    CAS:
    <p>Aumitin inhibits autophagy (IC50: 0.12-0.24μM), targets complex I, and blocks mitochondrial respiration.</p>
    Fórmula:C24H20ClN5O
    Pureza:99.13%
    Forma y color:Solid
    Peso molecular:429.9
  • Deferoxamine Mesylate

    CAS:
    <p>Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.</p>
    Fórmula:C26H52N6O11S
    Pureza:94.68% - 99.8%
    Forma y color:Solid
    Peso molecular:656.79
  • Oxidopamine hydrochloride

    CAS:
    <p>Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.</p>
    Fórmula:C8H12ClNO3
    Pureza:98.34% - 99.85%
    Forma y color:Physical Description Beige Solid (Ntp 1992)
    Peso molecular:205.64
  • Isoliquiritigenin

    CAS:
    <p>Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.</p>
    Fórmula:C15H12O4
    Pureza:97.61% - 99.44%
    Forma y color:Powder
    Peso molecular:256.25
  • Letrozole

    CAS:
    <p>Letrozole (CGS 20267) is an Aromatase Inhibitor. The mechanism of action of letrozole is as an Aromatase Inhibitor.</p>
    Fórmula:C17H11N5
    Pureza:98.67% - 99.84%
    Forma y color:White To Off-Whitecrystalline Powder
    Peso molecular:285.3
  • Luteolin

    CAS:
    <p>Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.</p>
    Fórmula:C15H10O6
    Pureza:96.61% - 99.71%
    Forma y color:Solid
    Peso molecular:286.24
  • Erlotinib

    CAS:
    <p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>
    Fórmula:C22H23N3O4
    Pureza:98.19% - 99.98%
    Forma y color:White To Off-White Powder
    Peso molecular:393.44
  • Theophylline

    CAS:
    <p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>
    Fórmula:C7H8N4O2
    Pureza:99.65% - 99.98%
    Forma y color:White Solid Powder
    Peso molecular:180.16
  • Rhein

    CAS:
    <p>Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.</p>
    Fórmula:C15H8O6
    Pureza:99.04%
    Forma y color:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)
    Peso molecular:284.22
  • Bergenin

    CAS:
    <p>Bergenin (Bengenin) is a polyphenol, which is an effective antinarcotic agent with antioxidant action.</p>
    Fórmula:C14H16O9
    Pureza:99.55% - 99.60%
    Forma y color:The Loose White Needle Crystal Powder Or Crystalline
    Peso molecular:328.27
  • Carvedilol phosphate hemihydrate

    CAS:
    <p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>
    Fórmula:C24H26N2O4·5H2O·H3O4P
    Pureza:99.24% - 99.98%
    Forma y color:Solid
    Peso molecular:513.49
  • Rosuvastatin calcium

    CAS:
    <p>Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic</p>
    Fórmula:(C22H27FN3O6S)Ca
    Pureza:98.21% - 99.68%
    Forma y color:White To Off-White Crystalline Solid
    Peso molecular:1001.14