Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1459 productos de "Autofagia"
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10074-G5
CAS:<p>10074-G5 is an inhibitor of c-Myc-Max dimerization.</p>Fórmula:C18H12N4O3Pureza:99.51% - 99.67%Forma y color:SolidPeso molecular:332.31KN-93
CAS:<p>KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.</p>Fórmula:C26H29ClN2O4SPureza:99.56% - 99.86%Forma y color:White SolidPeso molecular:501.04Taxifolin
CAS:<p>Taxifolin (Dihydroquercetin) is a flavonoid in many plants such as Taxus chinensis, Siberian larch, Cedrus deodara and so on.</p>Fórmula:C15H12O7Pureza:94.91% - 98.9%Forma y color:Yellowish PowderPeso molecular:304.25RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Fórmula:C24H16F6N6OPureza:99.56%Forma y color:SolidPeso molecular:518.41D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Fórmula:C5H10N2O3Pureza:99.99%Forma y color:White Or Off-White PowderPeso molecular:146.14IU1
CAS:IU1 是一种可逆的特异性人类 USP14 蛋白酶体抑制剂，可以穿透细胞，IC50为 4.7 μM。Fórmula:C18H21FN2OPureza:98% - 99.3%Forma y color:SolidPeso molecular:300.37PF-3845
CAS:PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Fórmula:C24H23F3N4O2Pureza:99.54% - 99.58%Forma y color:SolidPeso molecular:456.46Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Fórmula:C10H17NO3Pureza:98.75% - 99.57%Forma y color:SolidPeso molecular:199.25ML-SA1
CAS:<p>ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity.</p>Fórmula:C22H22N2O3Pureza:99.34% - 99.71%Forma y color:SolidPeso molecular:362.42Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31NH125
CAS:<p>NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.</p>Fórmula:C27H45IN2Pureza:98.60%Forma y color:SolidPeso molecular:524.56CX546
CAS:CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.Fórmula:C14H17NO3Pureza:99.75%Forma y color:SolidPeso molecular:247.295-Aminolevulinic acid hydrochloride
CAS:5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.Fórmula:C5H10ClNO3Pureza:98% - 99.97%Forma y color:White To Pale Yellow Crystals OrPeso molecular:167.59Ulipristal acetate
CAS:Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Fórmula:C30H37NO4Pureza:98.83% - 99.94%Forma y color:SolidPeso molecular:475.62Carfilzomib
CAS:Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Forma y color:SolidPeso molecular:719.91Nidufexor
CAS:Nidufexor is an agonist for the farnesoid X receptor (FXR).Fórmula:C27H22ClN3O4Pureza:98.67%Forma y color:SolidPeso molecular:487.93Berberine
CAS:<p>1.</p>Fórmula:C20H18NO4Pureza:95.71% - 99.67%Forma y color:SolidPeso molecular:336.36Ginkgetin
CAS:Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.Fórmula:C32H22O10Pureza:98.63% - 99.94%Forma y color:SolidPeso molecular:566.51Rilmenidine Phosphate
CAS:<p>Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.</p>Fórmula:C10H19N2O5PPureza:99.87% - ≥95%Forma y color:SolidPeso molecular:278.24Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Fórmula:C4H11N5Pureza:99.77% - >99.99%Forma y color:SolidPeso molecular:129.16
