Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1459 productos de "Autofagia"
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Shogaol
CAS:<p>6-Shogaol: anti-inflammatory, analgesic, antipyretic, protects cartilage, arrests cancer cell growth, inhibits metastasis.</p>Fórmula:C17H24O3Pureza:98.26% - 99.93%Forma y color:SolidPeso molecular:276.37Dapivirine
CAS:Dapivirine (R147681) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.Fórmula:C20H19N5Pureza:98% - 99.77%Forma y color:SolidPeso molecular:329.4Irinotecan
CAS:<p>Irinotecan (CPT-11), a camptothecin derivative, inhibits topoisomerase I, used for colorectal cancer treatment.</p>Fórmula:C33H38N4O6Pureza:98% - 99.92%Forma y color:SolidPeso molecular:586.68LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Fórmula:C26H27N5O2Pureza:97% - 99.83%Forma y color:SolidPeso molecular:441.52trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Fórmula:C29H33NO4Pureza:99.51%Forma y color:SolidPeso molecular:459.58Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Fórmula:C13H16N2O2Pureza:98% - 99.89%Forma y color:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28Peiminine
CAS:<p>1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.</p>Fórmula:C27H43NO3Pureza:99.52% - ≥95%Forma y color:White PowderPeso molecular:429.64Ridaforolimus
CAS:<p>Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。</p>Fórmula:C53H84NO14PPureza:90.00% - 98.55%Forma y color:Off-White SolidPeso molecular:990.21Oroxylin A
CAS:<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Fórmula:C16H12O5Pureza:98.72% - 99.55%Forma y color:SolidPeso molecular:284.26SBI-0640756
CAS:SBI-0640756 (SBI-756) (SBI-756) is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex.Fórmula:C23H14ClFN2O2Pureza:99.75%Forma y color:SolidPeso molecular:404.82Enzalutamide
CAS:<p>Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).</p>Fórmula:C21H16F4N4O2SPureza:99% - 99.93%Forma y color:SolidPeso molecular:464.44Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Fórmula:C21H24O6Pureza:98% - 99.51%Forma y color:SolidPeso molecular:372.41PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Fórmula:C9H15NO3Pureza:99.22%Forma y color:SolidPeso molecular:185.22Fexaramine
CAS:<p>Fexaramine is a small molecule farnesoid X receptor (FXR) agonist with 100-fold increased affinity compared to natural compounds.</p>Fórmula:C32H36N2O3Pureza:98.87% - 99.61%Forma y color:SolidPeso molecular:496.64GSK2656157
CAS:<p>GSK2656157 is a highly specific and ATP-competitive PERK inhibitor (IC50: 0.9 nM) in a cell-free assay.</p>Fórmula:C23H21FN6OPureza:98.59% - >99.99%Forma y color:SolidPeso molecular:416.45PD-166866
CAS:<p>PD-166866 is a selective FGFR tyrosine kinase inhibitor.</p>Fórmula:C20H24N6O3Pureza:98.29%Forma y color:SolidPeso molecular:396.44ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Fórmula:C12H22ClN3OSPureza:99.3%Forma y color:SolidPeso molecular:291.84Pictilisib
CAS:<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Fórmula:C23H27N7O3S2Pureza:98.69% - 99.97%Forma y color:SolidPeso molecular:513.64SF1670
CAS:<p>SF1670 (PTPase CD45 Inhibitor) is a specific PTEN inhibitor with IC50 of 2 μM.</p>Fórmula:C19H17NO3Pureza:98.25% - 98.54%Forma y color:SolidPeso molecular:307.34Thiamet G
CAS:<p>Thiamet G is a selective O-GlcNAcase inhibitor (Ki=20 nM). The role of O-GlcNAcase is to remove O-GlcNAc from the modified protein. High-Quality, Low-Cost!</p>Fórmula:C9H16N2O4SPureza:99.06% - 99.98%Forma y color:SolidPeso molecular:248.3
