Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1459 productos de "Autofagia"
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Forskolin
CAS:Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).Fórmula:C22H34O7Pureza:98.83% - 99.96%Forma y color:Less Crystalline Solid Colorless Crystalline SolidPeso molecular:410.506-Thioguanine
CAS:6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Fórmula:C5H5N5SPureza:98.75% - >99.99%Forma y color:Odorless Or Almost Odorless Pale Yellow Crystalline PowderPeso molecular:167.19Calcineurin substrate acetate
<p>Calcineurin substrate acetate is from the regulatory RII subunit of cAMP-dependent protein kinase.</p>Fórmula:C94H154N28O31Pureza:97.59%Forma y color:SolidPeso molecular:2172.4Cinobufagin
CAS:<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Fórmula:C26H34O6Pureza:97.77% - 99.97%Forma y color:SolidPeso molecular:442.54Fludrocortisone acetate
CAS:<p>Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and</p>Fórmula:C23H31FO6Pureza:96.92% - 98.03%Forma y color:Crystalline SolidPeso molecular:422.49Vinblastine sulfate
CAS:<p>Vinblastine sulfate (Vincaleukoblastine sulfate salt) can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).</p>Fórmula:C46H58N4O9·H2SO4Pureza:97.81% - 99.68%Forma y color:White PowderPeso molecular:909.06Tacrolimus
CAS:<p>Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein</p>Fórmula:C44H69NO12Pureza:98% - 99.94%Forma y color:White Or Off-White Crystalline PowderPeso molecular:804.02Glycycoumarin
CAS:Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.Fórmula:C21H20O6Pureza:97.64% - 99.78%Forma y color:SolidPeso molecular:368.38PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Fórmula:C17H13Br2N5OSPureza:99.43% - 99.887%Forma y color:SolidPeso molecular:495.19S29434
CAS:S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).Fórmula:C21H18N4O3Pureza:99.92%Forma y color:SolidPeso molecular:374.39PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Fórmula:C22H19BrF2N2O3Pureza:97.90% - 98.27%Forma y color:SolidPeso molecular:477.3Isradipine
CAS:<p>Isradipine (PN 200-110), a dihydropyridine, is an antihypertensive calcium channel blocker that dilates arteries and reduces resistance.</p>Fórmula:C19H21N3O5Pureza:99.84% - 99.95%Forma y color:Yellow SolidPeso molecular:371.39AM580
CAS:<p>AM580 (CD336) is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM )</p>Fórmula:C22H25NO3Pureza:98% - 99.89%Forma y color:SolidPeso molecular:351.44Bakuchiol
CAS:<p>Bakuchiol: anti-tumor, anti-helminthic, DNA polymerase1 inhibitor, cytotoxic, and anti-bacterial, may prevent dental caries.</p>Fórmula:C18H24OPureza:98.04% - 99.05%Forma y color:Brownish Yellow Liquid ViscousPeso molecular:256.38IKK 16
CAS:IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.Fórmula:C28H29N5OSPureza:98.76% - 99.61%Forma y color:SolidPeso molecular:483.63NL-1
CAS:NL-1 is a mitoNEET inhibitor with antileukemic effect.Fórmula:C18H25NO3SPureza:98.64%Forma y color:SolidPeso molecular:335.46JH-II-127
CAS:<p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>Fórmula:C19H21ClN6O3Pureza:98.32%Forma y color:SolidPeso molecular:416.86Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Fórmula:C17H18N6Pureza:99.4% - >99.99%Forma y color:SolidPeso molecular:306.36Silibinin
CAS:<p>Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.</p>Fórmula:C25H22O10Pureza:97.98% - 98.37%Forma y color:SolidPeso molecular:482.44
