Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Autophagy inducer 4
CAS:<p>Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.</p>Fórmula:C32H37NO6Forma y color:SolidPeso molecular:531.64PX20606 trans racemate
CAS:<p>PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).</p>Fórmula:C29H22Cl3NO4Pureza:98%Forma y color:SolidPeso molecular:554.85MF-095
CAS:<p>MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.</p>Fórmula:C27H31N3O4SForma y color:SolidPeso molecular:493.62Momelotinib Mesylate
CAS:<p>Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.</p>Fórmula:C24H26N6O5SPureza:98%Forma y color:SolidPeso molecular:510.57IT1t
CAS:<p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>Fórmula:C21H34N4S2Pureza:98%Forma y color:SolidPeso molecular:406.65PF 750
CAS:<p>PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.</p>Fórmula:C22H23N3OPureza:99.87%Forma y color:SolidPeso molecular:345.44Metofenazate
CAS:<p>Metofenazate is an selective inhibitor of calmodulin .</p>Fórmula:C31H36ClN3O5SPureza:98%Forma y color:SolidPeso molecular:598.15MRT-68601 HCl
CAS:<p>MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.</p>Fórmula:C25H34N6O2Pureza:98%Forma y color:SolidPeso molecular:450.58Evogliptin
CAS:<p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>Fórmula:C19H26F3N3O3Forma y color:SolidPeso molecular:401.42ATG7-IN-3
CAS:<p>ATG7-IN-3, or compound 18, is an ATG7 inhibitor with a 0.048 μM IC50, blocking autophagy and LC3B puncta in H4 cells.</p>Fórmula:C11H16N6O5S2Pureza:99.88%Forma y color:SolidPeso molecular:376.41SB02024
CAS:<p>SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.</p>Fórmula:C16H22F3N3O2Forma y color:SolidPeso molecular:345.36YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Fórmula:C20H19ClN4O3Forma y color:SolidPeso molecular:398.85OSU-53
CAS:<p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>Fórmula:C25H24F3N3O6S2Forma y color:SolidPeso molecular:583.6TUN-92046
CAS:<p>TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.</p>Fórmula:C7H10O5Pureza:95.48% - 98.58%Forma y color:SolidPeso molecular:174.15VUF5834
CAS:<p>VUF5834 is a full inverse agonist of CXCR3 N3.35A.</p>Fórmula:C31H41N5O2Pureza:98%Forma y color:SolidPeso molecular:515.69LV-320
CAS:<p>LV-320, potent ATG4B inhibitor; IC50: 24.5 μM, Kd: 16 μM. Blocks autophagy, stable, non-toxic, active in vivo. Useful for ATG4B research in cancer.</p>Fórmula:C29H26ClNO2S2Pureza:98%Forma y color:SolidPeso molecular:520.11SA 47
CAS:<p>SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.</p>Fórmula:C17H26N4O3Pureza:98%Forma y color:SolidPeso molecular:334.41YOK-2204
CAS:<p>YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.</p>Fórmula:C28H35NO4Forma y color:SolidPeso molecular:449.58Rimacalib
CAS:<p>Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).</p>Fórmula:C22H23FN4O2Pureza:98%Forma y color:SolidPeso molecular:394.44Nicodicosapent
CAS:<p>Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.</p>Fórmula:C28H39N3O2Pureza:98%Forma y color:SolidPeso molecular:449.63
