Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1427 productos de "Autofagia"
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CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Forma y color:SolidPeso molecular:341.84SR12418
CAS:<p>SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.</p>Fórmula:C31H30FNO3Pureza:99.96%Forma y color:SolidPeso molecular:483.57IT1t
CAS:<p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>Fórmula:C21H34N4S2Pureza:98%Forma y color:SolidPeso molecular:406.65CUR5g
CAS:<p>CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.</p>Fórmula:C22H20N2O2Pureza:98.92%Forma y color:SolidPeso molecular:344.41Amsacrine
CAS:<p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>Fórmula:C21H19N3O3SPureza:99.2%Forma y color:Yellow Crystalline Powder SolidPeso molecular:393.46Autophagy inducer 3
CAS:<p>Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.</p>Fórmula:C24H43NO2Forma y color:SolidPeso molecular:377.6Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Fórmula:C20H34O5Pureza:97.94% - 98.04%Forma y color:White To Off-White Crystalline SolidPeso molecular:354.48AMG 487 (S-enantiomer)
CAS:<p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>Fórmula:C32H28F3N5O4Pureza:98%Forma y color:SolidPeso molecular:603.59Evogliptin
CAS:<p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>Fórmula:C19H26F3N3O3Forma y color:SolidPeso molecular:401.42ATG7-IN-3
CAS:<p>ATG7-IN-3, or compound 18, is an ATG7 inhibitor with a 0.048 μM IC50, blocking autophagy and LC3B puncta in H4 cells.</p>Fórmula:C11H16N6O5S2Pureza:99.88%Forma y color:SolidPeso molecular:376.41Xantocillin
CAS:<p>Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.</p>Fórmula:C18H12N2O2Pureza:98%Forma y color:SolidPeso molecular:288.3YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Fórmula:C20H19ClN4O3Forma y color:SolidPeso molecular:398.85OSU-53
CAS:<p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>Fórmula:C25H24F3N3O6S2Forma y color:SolidPeso molecular:583.6ABTL-0812
CAS:<p>ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.</p>Fórmula:C18H32O3Forma y color:SolidPeso molecular:296.44HF50731
CAS:<p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>Fórmula:C26H46N4Forma y color:SolidPeso molecular:414.67(Rac)-BL-918
CAS:<p>(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.</p>Fórmula:C23H15F8N3OSPureza:98%Forma y color:SolidPeso molecular:533.44FAAH inhibitor 1
CAS:<p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>Fórmula:C24H23N3O3S3Pureza:99.6%Forma y color:SolidPeso molecular:497.65GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Fórmula:C24H35N3O4Pureza:99.37%Forma y color:SolidPeso molecular:429.55MDK-6983
CAS:<p>MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.</p>Fórmula:C22H18Cl2N2O3Pureza:99.68%Forma y color:SolidPeso molecular:429.3MRT-68601 HCl
CAS:<p>MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.</p>Fórmula:C25H34N6O2Pureza:98%Forma y color:SolidPeso molecular:450.58
